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3篇 您的检索式:作者名="Saima RASHEED"
    题名 作者 年代 出处 被引量
1Cyclopeptide alkaloids of Ziziphus oxyphylla Edgw as novel inhibitors of α-glucosidase enzyme and protein glycation显示文摘M. Iqbal Choudhary Achyut Adhikari Saima Rasheed Bishnu P. Marasini Nusrat Hussain Waqar Ahmad Kaleem Atta-ur-Rahman 2011Phytochemistry Letters2011,,4:1
2Parmotrema cooperi中的新型抗醣化物质和酶抑制剂显示文摘地衣是被广泛用于传统药物中的独特个体.本文对一类地衣,Parmotrema cooperi,进行了生物测定引导的植物化学研究和生物活性评价.对该类地衣的首次生物测定引导的化学研究分离出了化合物ethyl heamatomate(1),atraric acid(2),ethyl orsellinate(3),orsellinic acid(4),lecanoric acid(5),gyrophoric acid(6)以及licanorin(7).化合物1~7的结构主要通过一维、二维核磁共振谱和质谱等谱学方法判定.对这些化合物还进行了抗醣化活性以及尿素酶、α-胰凝乳蛋白酶、β-葡萄糖醛酸苷酶抑制活性的评价.这些苯酚化合物没有显示特别好的活性,但其中大部分对蛋白质醣化和尿素酶活性具有较好的抑制作用.M.Iqbal CHOUDHARY Meher ALI Atia-tul-WAHAB Ajmal KHAN Saima Rasheed Sajan Lal SHYAULA(Shrestha) Atta-ur-RAHMAN 陈洁 2012中国科学:化学2012,42,1:1
3New antiglycation and enzyme inhibitors from Parmotrema cooperi显示文摘Lichens are unique individuals which have been widely used in traditional medicines.This study was focused on the bioassay-guided phytochemical investigation,and bioactivity evaluation on a lichens species,Parmotrema cooperi.This first bioassay-directed chemical study on P.cooperi has led to the isolation of ethyl heamatomate(1),atraric acid(2),ethyl orsellinate(3),orsellinic acid(4),lecanoric acid(5),gyrophoric acid(6),and licanorin(7).The structures of 1-7 were mainly elucidated from spectroscopic methods including 1D,and 2D NMR spectroscopy,and mass spectrometry.These compounds were evaluated for their antiglycation,urease,α-chymotrypsin,and β-glucoronidase inhibitory activities.Few of the phenolic compounds showed significant,while most of them showed good inhibition of protein glycation,and urease activities.M.Iqbal CHOUDHARY Meher ALI Atia-tul-WAHAB Ajmal KHAN Saima RASHEED Sajan Lal SHYAULA(Shrestha) Atta-ur-RAHMAN 2011Science China Chemistry2011,54,12:1
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