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| 1 | Drainage vs. non-drainage after cholecystectomy for acute cholecystitis:a retrospective study显示文摘Many surgeons practice prophylactic drainage after cholecystectomy without reliable evidence,this study was conducted to answer the question whether to drain or not to drain after cholecystectomy for acute calculous cholecystitis.A retrospective review of all patients who had cholecystectomy for acute cholecystitis in Aseer Central Hospital,Abha,Saudi Arabia,was conducted from April 2010 to April 2012.Data were extracted from hospital case files.Preoperative data included clinical presentation,routine investigations and liver function tests.Operative data included excessive adhesions,bleeding,bile leak,and drain insertion.Complicated cases such as pericholecystic collections,mucocele and empyema were also reported.Patients who needed therapeutic drainage were excluded.Postoperative data included hospital stay,volume of drained fluid,time of drain removal,and drain site problems.The study included 103 patients allocated into two groups;group A(n = 38) for patients with operative drain insertion and group B(n = 65) for patients without drain insertion.The number of patients with preoperative diagnosis of acute non-complicated cholecystitis was significantly greater in group B(80%) than group A(36.8%)(P < 0.001).Operative time was significantly longer in group A.All patients who were converted from laparoscopic to open cholecystectomy were in group A.Multivariate analysis revealed that hospital stay was significantly(P < 0.001) longer in patients with preoperative complications.There was no added benefit for prophylactic drain insertion after cholecystectomy for acute calculous cholecystitis in non-complicated or in complicated cases. | Mohammed A Bawahab Walid M Abd El Maksoud Saeed A Alsareii Fahad S Al Amri Hala F Ali Abdul Rahman Nimeri Abdul Rahman M Al Amri Adel A Assiri Mohammed I Abdul Aziz | 2014 | The Journal of Biomedical Research2014，28，3： | 3 |
| 2 | Efficacy and safety of treatment of hepatitis C virus infection in renal transplant recipients显示文摘AIM: To assess the efficacy and safety of combinedpegylated interferon and ribavirin therapy in hepatitis C virus (HCV) infection in renal transplant recipients. METHODS: This is a retrospective chart review of post renal transplant patients who were positive for anti-HCV and HCV-RNA, and who have received treatment with combination of pegylated interferon and ribavirin between October 2003 and December 2008. Only patients with stable graft function and absence of evidence of cirrhosis and who received the therapy for continuous 48 wk were included. Nineteen patients (13 male and 6 female) were identified and included. The patient's complete blood count, liver and kidney prof ile, and cal- culated glomerular f iltration rate (GFR) were monitored every 6-8 wk while on treatment. HCV-RNA was tested at 12 wk for early virological response, at 48 wk for end of treatment response (ETR), and then retested at 24, and 48 wk after completion of therapy for sustained virological response (SVR). Liver biopsies were obtained before treatment from all patients and graft kidney biopsies were performed as required. RESULTS: Of the entire cohort, 9 patients (47.4%) showed an ETR and 8 had SVR (42.1%). Of the 8 patients with abnormal alanine aminotransferase (ALT) levels at baseline, 78.9% had their ALT normalized (including the virological non responders). ALT was normal in all responders at the end of therapy and at 24 wk post therapy (100%). Only one patient (5.3%) developed an increase in creatinine and decline in GFR from baseline towards the end of treatment. This patient's kidney biopsy revealed borderline rejection. There was no impact on response by HCV-genotype, initial HCV RNA load, age or sex of the patient or duration post transplant before commencement of therapy. All patients tolerated treatment in the same way as non-transplant with no unusual or increased occurrence of side effects. CONCLUSION: The combination of pegylated interferon and ribavirin is effective in suppressing HCV-RNA,with a low risk of graft rejection or failure in HCV infected renal transplant recipients. | Abdulrahman A Aljumah Mohamed A Saeed Ahmed I Al Flaiw Ibrahim H Al Traif Abduljaleel M Al Alwan Salem H Al Qurashi Ghormallah A Al Ghamdi Fayez F Al Hejaili Mohammed A Al Balwi Abdulla A Al Sayyari | 2012 | World Journal of Gastroenterology2012，18，1： | 2 |
| 3 | Fibrocytes induce an angiogenic phenotype in cultured endothelial cells and promote angiogenesis in vivo 显示文摘 | Hartlapp I Abe R Saeed RW | 2001 | Faseb J2001，15，12： | 1 |
| 4 | Ocular injury requiring hospi- talisation in the south east of Ireland: 2001-2007 显示文摘 | Saeed A Khan I Dunne O | 2010 | Injury2010，41，1： | 1 |
| 5 | Comparison between Double J(DJ)Ureteral Stenting and Percutaneous Nephrostomy(PCN)in Obstructive Uropathy显示文摘 | Ahmad I Saeed Pansota M Tariq M | 2013 | Pak J Med Sci2013，29，3： | 1 |
| 6 | Preparation and properties of single-walledcarbon nanotubes/poly( butylene terephthalate) nanocomposites 显示文摘 | SAEED K KHAN I | 2014 | Iranian Polymer Journal2014，23，1： | 1 |
| 7 | Noncompaction of the left ven- tricular myocardium显示文摘 | Saeed S vcqsundvaq J lode I | 2009 | Tidsskr Nor Laegeforen2009，129，11： | 1 |
| 8 | Helminths of red foxes (Vulpes vulpes) in Denmark显示文摘 | Saeed I Maddox-Hyttel C Monrad J | 2006 | Vet Parasitol2006，139，13： | 1 |
| 9 | Potential of partial root- zone drying as an alternative irrigation technique for potatoes( Solarium tuberosum) 显示文摘 | Saeed H Grove I G Kettlewell P S | 2008 | Annals of Applied Biology2008，152，1： | 1 |
| 10 | Emergence of methicillin-resistant Staphylococcus aureus as a community pathogen显示文摘 | Bukharie H A Abdelhadi M S Saeed I A etal | 2001 | Diagn Microbiol Infect Dis2001，40，12： | 1 |
| 11 | FTIR spectrophotometry, kinetics and adsorption isotherms modeling, ion exchange, and EDX analysis for understanding the mechanism of Cd2 + and Pb2 + removal by mango peel waste 显示文摘 | Iqbal M Saeed A Zafar S I | 2009 | Journal of Hazardous Materials2009，164，： | 1 |
| 12 | Synthesis, characterization and biological activities of some new organotin(IV) derivatives: Crystal structure of 显示文摘 | Rauf MK Saeed MA Din I | 2008 | J Organomet Chem2008，693，： | 1 |
| 13 | FTIR spectrophotometry,kinetics and adsorption isotherms modeling,ion exchange,and EDX analysis for understanding the mechanism of Cd2+ and Pb2 + removal by mango peel waste显示文摘 | IQBAL M SAEED A ZAFAR S I | 2009 | Journal of Hazardous Materials2009，164，1： | 1 |
| 14 | Randomized clinical trial of human interleukin-11 in Dengue fever-associated thromboeytopenia 显示文摘 | Suliman MI Qayum I Saeed F | 2014 | J Coil PhYsicians Surg Pak2014，24，3： | 1 |
| 15 | 显示文摘 | Hartlapp I Abe R Saeed RW | | (12) :2215-22240，，12： | 1 |
| 16 | Malignant phyllodes tumour as an intracystic growth with osteosarcomatous differentiation显示文摘 | Saeed S A Masroor I | 2009 | J Coll Physicians Surg Pak2009，19，11： | 1 |
| 17 | Diagnostic performance of breast MRI in the evaluation of contralateral breast in patients with diagnosed breast cancer显示文摘 | Saeed SA Masreor I Beg M | 2015 | Asian Pac J Cancer Prey2015，16，17： | 1 |
| 18 | Orbital irradiation for Graves' ophthahnopathy: is it safe? A long-term follow-up study 显示文摘 | Wakelkamp I M Tan H Saeed P | 2004 | Ophthalmology2004，111，8： | 1 |
| 19 | TM4 microarray software suite显示文摘 | SAEED A I BHAGABATI N K BRAISTED J C | 2006 | Methods in Enzymology2006，411，： | 1 |
| 20 | Irrigation effects on the growth yield and water use efficiency of alfalfa显示文摘 | Saeed I A M El-Nadi | 1997 | Irrigation Science1997，17，2： | 1 |
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