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| 1 | Two-dimensional speckle tracking echocardiography for the assessment of atrial function显示文摘Echocardiography is the most common diagnostic method for assessing atrial function but the technique has some limitations. Traditionally, assessment of left atrial function has been performed by measuring volumes with 2D echocardiography. Additionally, it can be assessed with transmitral Doppler and pulmonary vein Doppler. Recently, an alternative method has been incorporated, namely, measurement of myocardial deformation with color tissue Doppler-derived strain. However, this method has several limitations, such as suboptimal reproducibility, angle-dependence, signal artifacts and the fact that it only measures regional strain and does not obtain information about the curved portion of the atrial roof. To overcome these limitations in the quantification of atrial function, the use of speckle tracking echocardiography (STE) strain has been proposed. This technique is not derived from Doppler but rather from 2D echocardiography; it is angle-independent and allows one to measure global as well as regional atrial strain. In this editorial, we describe the physical and pathophysiological concepts of STE and underline the clinical usefulness of this new technique. | Tomás Francisco Cianciulli María Cristina Saccheri Jorge Alberto Lax Alejandra Marina Bermann Daniel Ernesto Ferreiro | 2010 | World Journal of Cardiology2010，2，7： | 39 |
| 2 | Speckle tracking echocardiography to assess regional ventricular function in patients with apical hypertrophic cardiomyopathy显示文摘AIM To explore regional systolic strain of midwall and endocardial segments using speckle tracking echocardiography in patients with apical hypertrophic cardiomyopathy(HCM).METHODS We prospectively assessed 20 patients(mean age 53 ± 16 years,range:18-81 years,10 were male),with apical HCM. We measured global longitudinal peak systolic strain(GLPSS) in the midwall and endocardium of the left ventricle. RESULTS The diastolic thickness of the 4 apical segments was 16.25 ± 2.75 mm. All patients had a normal global systolicfunction with a fractional shortening of 50% ± 8%. In spite of supernormal left ventricular(LV) systolic function,midwall GLPSS was decreased in all patients,more in the apical(-7.3% ±-8.8%) than in basal segments(-15.5% ±-6.93%),while endocardial GLPPS was significantly greater and reached normal values(apical:-22.8% ±-7.8%,basal:-17.9% ±-7.5%). CONCLUSION This study shows that two-dimensional strain was decreased mainly confined to the mesocardium,while endocardium myocardial deformation was preserved in HCM and allowed to identify subclinical LV dysfunction. This transmural heterogeneity in systolic strain had not been previously described in HCM and could be explained by the distribution of myofibrillar disarray in deep myocardial areas. The clinical application of this novel finding may help further understanding of the pathophysiology of HCM. | María Cristina Saccheri Tomás Francisco Cianciulli Luis Alberto Morita Ricardo JoséMéndez Martín Alejandro Beck Juan Enrique Guerra Alberto Cozzarin Luciana Jimena Puente Lorena Romina Balletti Jorge Alberto Lax | 2017 | World Journal of Cardiology2017，9，4： | 7 |
| 3 | Complete regression of myocardial involvement associated with lymphoma following chemotherapy显示文摘Cardiac involvement as an initial presentation of malignant lymphoma is a rare occurrence.We describe the case of a 26 year old man who had initially been diagnosed with myocardial infiltration on an echocardiogram,presenting with a testicular mass and unilateral peripheral facial paralysis.On admission,electrocardiograms(ECG)revealed negative T-waves in all leads and ST-segment elevation in the inferior leads.On twodimensional echocardiography,there was infiltration of the pericardium with mild effusion,infiltrative thickening of the aortic walls,both atria and the interatrial septum and a mildly depressed systolic function of both ventricles.An axillary biopsy was performed and reported as a T-cell lymphoblastic lymphoma(T-LBL).Following the diagnosis and staging,chemotherapy was started.Twenty-two days after finishing the first cycle of chemotherapy,the ECG showed regression of T-wave changes in all leads and normalization of the ST-segment elevation in the inferior leads.A followup two-dimensional echo confirmed regression of the myocardial infiltration.This case report illustrates a lymphoma presenting with testicular mass,unilateral peripheral facial paralysis and myocardial involvement,and demonstrates that regression of infiltration can be achieved by intensive chemotherapy treatment.To our knowledge,there are no reported cases of T-LBL presenting as a testicular mass and unilateral peripheral facial paralysis,with complete regression of myocardial involvement. | Juan Pablo Vinicki Tomás F Cianciulli Gustavo A Farace María C Saccheri Jorge A Lax Lucía R Kazelián Adolfo Wachs | 2013 | World Journal of Cardiology2013，5，9： | 2 |
| 4 | Inbreeding and extinction in a butterfly meta population显示文摘 | Saccheri I Kuussaari M Kankare M | 1998 | Nature1998，392，： | 1 |
| 5 | Segmental transcatheter arterial chemoembolization treatment in patients with cirrhosis and inoperable hepatocellular carcinoma 显示文摘 | Saccheri S Lovaria A Sangiovanni A | 2002 | J Vasc Interv Radiol2002，13，： | 1 |
| 6 | Cytogenetic Charac- terization and AFLP-Based Genetic Linkage Mapping for the Butterfly Bicyclus anynana, Covering All 28 Karyotyped Chromo- somes显示文摘 | Van't Hof AE M arec F Saccheri U | 2008 | PLoS ONE2008，3，12： | 1 |
| 7 | Inbreeding and extinction in a batterfly metapopulation显示文摘 | Saccheri I Kuussaari M Kankare M | 1998 | Nature1998，，392： | 1 |
| 8 | Esophageal Carcinoma and Transthoracic Echocardiography显示文摘 | Tomás F. Cianciulli María C. Saccheri Jorge A. Lax Ricardo A. Bianchi Martín A. Beck Daniel E. Ferreiro | 2013 | Echocardiography2013，，9： | 1 |
| 9 | A keyhole-shaped sternal defect in an ancient human skeleton显示文摘 | Saccheri P Sabbadini G Toso F | | 0，，： | 1 |
| 10 | Aterial embolization in the treatment of the post-traumatic priapism显示文摘 | Colombo F Lovaria A Saccheris | 1999 | Ann Urol1999，33，3： | 1 |
| 11 | Inbreeding and extinction in a but2 terfly rnetapopulation显示文摘 | Saccheri I Kuussaari M Kankare M | 1998 | Nature1998，392，： | 1 |
| 12 | Usefulness of pulsed Doppler tissue imaging in the early detection of diastolic myocardial abnormalities in first-degree relatives of patients with familial hypertrophic cardiomyopathy 显示文摘 | Saccheri MC Cianciulli TF Konopka IV | 2006 | Rev Esp Cardiol2006，59，1： | 1 |
| 13 | Echocardio- graphic evaluation of mitral valve repair by modified ' edge to edge' technique 显示文摘 | Cianciulli TF Lax JA Saccheri MC | 2006 | Echocardiography2006，23，9： | 1 |
| 14 | Allee effect and population dynamics in the Glanville fritillary butterfly显示文摘 | Kuussaari M Saccheri I Camara M | 1998 | Oikos1998，，82： | 1 |
| 15 | Arterial embolization in the treatment of post-traumatic priapism显示文摘 | Colombo F Lovaria A Saccheri S | 1999 | Ann Urol(Paris)1999，33，3： | 1 |
| 16 | Myocardial perfusion SPECT in the diagnosis of apical hypertrophic cardiomyopathy显示文摘 | Cianciulli TF Saccheri MC Masoli OH | 2009 | J Nucl Cardiol2009，16，3： | 1 |
| 17 | Arterial embolization in the treatment of postranmatic priapism显示文摘 | Colombo F Lovaria A Saccheri S | 1999 | Ann Urol Paris1999，33，3： | 1 |
| 18 | Segmental Transcatheter Arterial Chemoembolization Treatment in Patients with Cirrhosis and Inoperable Hepatocellular Carcinomas显示文摘 | Silvia Saccheri Andrea Lovaria Angelo Sangiovanni Antonio Nicolini Cristina De Fazio Guido Ronchi Pierangelo Fasani Ersilio Del Ninno Massimo Colombo | 2002 | Journal of Vascular and Interventional Radiology2002，，10： | 1 |
| 19 | Industrial melanism in the peppered moth isnot associated with genetic variation in canonical melanisation gene candi-dates显示文摘 | HOF A E V SACCHERI I J | 2010 | PLoS One2010，5，10： | 1 |
| 20 | Industrial melanism in British peppered moths has a singular and recent mutational origin显示文摘 | van't Hof AE Edmonds N Dalíková M Marec F Saccheri IJ | | 0，，： | 1 |
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