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| 1 | Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior显示文摘服的外皮为集成是必要的并且为大多数行为被要求的信息处理。当神经原从室的地区连续地移居联合进特定的外皮的层时,服的外皮的精致地精确的 laminar 组织在胚胎的开发期间产生。当时指南为设计神经原移植责骂的光线的神经胶质行为, pre-formed 脉管的网络为 GABAergic interneuron 移植提供支持和指导暗示。这研究提供新奇概念、机械学的卓见进 vascular-neuronal 相互作用的这个范例,揭示伽马氨基丁酸并且它经由胚胎的前脑 endothelial 房间的调停受体的发信号的新机制。与二个新 endothelial 房间的使用,特定的有条件的老鼠 GABA 小径当模特儿(Gabrb3 Tie2-Cre 和 Vgat 我们显示出的 Tie2-Cre ), 从 endothelial 房间的伽马氨基丁酸版本的那部分或完全的损失在 embryogenesis 期间导致脉管的缺点并且损害长途的移植并且外皮的 interneurons 放。使不安的 endothelial 的下游的效果导出房间的伽马氨基丁酸发信号是批评的,导致上次修改到外皮的电路和坚持的行为的赤字。而且,我们说明在支持他们血大脑障碍性质的迁居, angiogenesis 和获得的前脑 endothelial 房间发信号的伽马氨基丁酸的激活的新机制。我们的调查结果揭开并且阐明在从表明小径的古典 neuronal 伽马氨基丁酸是不同的并且在 neuropsychiatric 疾病的病原学和 pathophysiology 上打开新灯的 CNS 表明小径的新奇 endothelial 伽马氨基丁酸例如孤独性光谱混乱,癫痫,焦虑,消沉和精神分裂症。 | Suyan Li Peeyush Kumar Sampada Joshee Timo Kirschstein Sivan Subburaju Jahan S Khalili Jonas Kloepper Chuang Du Abdallah Elkhal Gabor Szabo Rakesh K Jain Rudiger Kohling Anju Vasudevan | 2018 | Cell Research2018，28，2： | 3 |
| 2 | Experimental model for production of perforating duodenal ulcers by cysteamine in the rat 显示文摘 | Selye H Szabo S | 1973 | Nature1973，244，： | 2 |
| 3 | Pathogenesis of duodenal ulcer:gastric hyperacidity caused by propionitrile and cysteamine in rats 显示文摘 | Szabo S Reynolds ES Lichtenberger | 1977 | Res Coun Chem Pathol Pharmacol1977，16，： | 2 |
| 4 | Distinct effects of T-bet in Th 1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells 显示文摘 | Szabo S J Sulliavan B M Stemmann C | 2002 | Science2002，295，11： | 1 |
| 5 | Histone deacetylase activities are required for innate immune cell control of Thl but not Th2 effector cell function显示文摘 | Brogdon J L Xu Y Szabo S J An S Buxton F Cohen D | 2007 | Blood2007，109，： | 1 |
| 6 | A novel transcription factor, T- bet, directs Thl lineage commitement显示文摘 | SZABO S J KIM S T COSTA G L | 2000 | Cell2000，100，6： | 1 |
| 7 | Clinical and laboratory observations Vitamin K-dependent clotting factors during long-term total parenter al nutrition in full-term and preterm infants显示文摘 | Bors S Szabo A | 1988 | J Pediatr1988，112，： | 1 |
| 8 | BRCA1 and BRCA2 sequence variants in Chinese breast cancer families显示文摘 | Zhi X Szabo C Chopin S | 2002 | Hum Mutat2002，20，6： | 1 |
| 9 | Gene expression and gene therapy in experimental duodenal ulceration显示文摘 | Szabo S Deng X Khomenko T | 2001 | J Physiol Paris2001，95，16： | 1 |
| 10 | Distributed CAN based control system for robotic and airborne applications 显示文摘 | Szabo S Oplustil V | 2002 | IEEE on Control Automation Robotics and Vision2002，3，11： | 1 |
| 11 | Cellular inflammatory infiltrate in pneumonitis induced by a single moderate dose of thoracic X radiation in rats显示文摘 | Szabo S Ghosh SN Fish BL | 2010 | Radiat Res2010，173，4： | 1 |
| 12 | Quality of life following a change in therapy for diabetes mellitus 显示文摘 | Pibernik-Okanovi6 M Szabo S Metelko Z | 1998 | Pharmaeoeconomics1998，14，2： | 1 |
| 13 | Transcriptional regulation of Th1/Th2 polarization显示文摘 | RENGARAJAN J SZABO S J GLIMCHER L H | 2000 | Immunol Today2000，21，10： | 1 |
| 14 | Molecular and cellular basis of ulcer healing 显示文摘 | SZABO S KUSSTATSCHER S SANDOR Z | | Scand J Gastroenterol0，，： | 1 |
| 15 | Gene therapy with adenoviral plasmids or naked DNA of vascular endothelial growth factor and platelet-derived growth factor accelerates healing of duodenal ulcer in rats显示文摘 | Deng X Szabo S Khomenko T | 2004 | J Pharmacol Exp Ther2004，311，3： | 1 |
| 16 | Sulfhydryl compounds may mediate gastric cytoprotection显示文摘 | Szabo S Trier JS Frankel PW | 1981 | Science1981，214，1： | 1 |
| 17 | Distributed CAN based control system for robotic and airborne applications显示文摘 | Szabo S Oplustil V | 2002 | IEEE on Control Automation Robotics and Vision2002，3，11： | 1 |
| 18 | Aged-associated defects in B lymphocyte development显示文摘 | Szabo P Shen S Weksler ME | 1999 | Exp Gerontol1999，，34： | 1 |
| 19 | New technique for aortoostial stentplaeement显示文摘 | Szabo S Abramowitz B Vaitkus PT | 2005 | Am J Cardiol2005，96，7： | 1 |
| 20 | Cellular inflammatoryinfiltrate in pneumonitis induced by a single moderate dose ofthoracicx radiation in rats显示文摘 | Szabo S Ghosh SN Fish BL | 2010 | Radiat Res2010，173，4： | 1 |
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