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| 1 | A Robust Measure of Skew-ness显示文摘 | Brys G Hubert M Struyf A | 2004 | Journal of Computational and Graphical Statistics2004，13，4： | 1 |
| 2 | The CXC chemokine GCP-2/ CXCL6 is predominantly induced in mesenchymal cells by inter- leukin-lbeta and is down-regulated by interferon-gamma:com- parison with interleukin-8/CXCL8显示文摘 | Wuyts A Struyf S Gijsbers K | 2003 | Lab Invest2003，83，1： | 1 |
| 3 | Displaying a clustering with CLUSPLOT 显示文摘 | PISON G STRUYF A ROUSSEEUW P J | 1999 | Computational Statistics & Data A- nalysis1999，30，4： | 1 |
| 4 | Computing location depth and regression depth in higher dimensions显示文摘 | Rousseeuw P J Struyf A | 1998 | Statistics and Computing1998，8，11： | 1 |
| 5 | 人乳头瘤病毒16/18型AS04佐剂疫苗预防肿瘤基因型HPV引起的宫颈感染和癌前病变的效应(PATRICIA):一项在年轻女性中进行的双盲、随机研究的最终分析显示文摘背景在年轻成人中进行的Ⅲ期随机、双盲对照PATRICIA试验(PApilloma TRial)的事件驱动期中分析显示,人乳头瘤病毒(HPV)16/18AS04佐剂疫苗具有免疫原性,且总体耐受性良好,对HPV16或HPV18感染及相关的癌前病变具有预防效应。本文作者旨在评估最终事件驱动分析中的疫苗效应。方法将在基线、1个月和6个月接种疫苗的15~25岁女性分类为符合方案的效应队列(ATP-E队列;疫苗组8093例,对照组8069例)、总接种队列(TVC;包括至少接种1剂疫苗的所有女性,而不考虑其基线HPV状态;代表普遍的年轻女性人群,包括性活跃者;疫苗组9319例,对照组9325例)和TVC-naive(无证据表明基线时存在肿瘤基因型HPV感染;代表无性行为女性;疫苗组5822例,对照组5819例)。主要终点是。在基线时血清和DNA均为阴性且在6个月时为相应类型(ATP-E队列)的女性中,评估疫苗对HPV16或HPV18相关性宫颈上皮内瘤变≥2级(CIN2+)的预防效应。该试验在ClinicalTrial.gov上的注册编码为NCT00122681.结果第3剂疫苗接种后平均随访34.9个月(s=6.4)。在主要分析中疫苗对HPV16/18相关性CIN2+的预防效应为92.9%(96.1%CI79.9%~98.3%),在对可能因多种肿瘤基因型HPV引起的病变(ATP-E队列)的分析中,其预防效应为98.1%(96.1%CI88.4%~100%)。不考虑病变HPVDNA时,疫苗对CIN2+的预防效应在TVC中为30.4%(96.1%CI16.4%~42.1%),在TVC-naive中为70.2%(96.1%CI54.7%~80.9%);而对CIN3+的相应效应在TVC中为33.4%(96.1%CI9.1%~51.5%).在TVC-naive中为87.0%(96.1%CI54.9%~97.7%).在预防12种非疫苗肿瘤基因型HPv相关性CIN2+的效应为54.0%(96.1%CI34.0%~68.4%:ATP-E队列)。在TVC中可见对HPV31、33和45相关性CIN2+的个体交叉保护效应。结论HPV16/18 AS04佐剂疫苗表现出对HPV16/18和非疫苗肿瘤基因型HPV相关性CIN2+较强的预防效应,而要获得整体预防效应就需要在更广泛的人群中进行大面积强化免疫计划。基金 葛兰素史克。 | J Paavonen P Naud J Salmeron C M Wheeler S-N Chow D Apter H Kitchener X Castellsague J C Teixeira S R Skinner J Hedrick U Jaisamrarn G Limson S Garland A Szarewski B Romanowski F Y Aoki T F Schwarz W A J Poppe F X Bosch D Jenkins K Hardt T Zahaf D Descamps F Struyf M Lehtinen G Dubin 周彩虹(译) | 2009 | 世界临床医学2009，，12： | 1 |
| 6 | A robust measure of skewness显示文摘 | Brys G Hubert M Struyf A | 2004 | Journal of Computational and Graphical Statistics2004，13，： | 1 |
| 7 | High-dimensional computation of the deepest location显示文摘 | Struyf A Rousseeuw P J | 2000 | Computational Statistics and Data Analysis2000，34，： | 1 |
| 8 | Tidal marshes and bi- ogenic silica recycling at the land-sea interface 显示文摘 | Struyf E Dausse A Van Damme S | 2006 | Limnology and Oceanography2006，51，： | 1 |
| 9 | Integrating Robust Clustering Techniques in S-plus显示文摘 | Struyf A Hubert M Rousseeuw P | 1997 | Computational Statistics and Data Analysis1997，，26： | 1 |
| 10 | Tidal marshes and biogenic silica recycling at the land-sea interface显示文摘 | Struyf E Dausse A Van Damme S | 2006 | Limnology and Oceanography2006，51，2： | 1 |
| 11 | Fluxes of water,sediments,and biogeochemical compounds in salt marshes显示文摘Tidal oscillations systematically flood salt marshes,transporting water,sediments,organic matter,and biogeochemical elements such as silica.Here we present a review of recent studies on these fluxes and their effects on both ecosystem functioning and morphological evolution of salt marshes.We reexamine a simplified model for the computation of water fluxes in salt marshes that captures the asymmetry in discharge between flood and ebb.We discuss the role of storm conditions on sediment fluxes both in tidal channels and on the marsh platform.We present recent methods and field instruments for the measurement of fluxes of organic matter.These methods will provide long-term data sets with fine temporal resolution that will help scientists to close the carbon budget in salt marshes.Finally,the main processes controlling fluxes of biogenic and dissolved silica in salt marshes are explained,with particular emphasis on the uptake by marsh macrophytes and diatoms. | Sergio Fagherazzi Patricia L Wiberg Stijn Temmerman Eric Struyf Yong Zhao Peter A Raymond | 2013 | Ecological Processes2013，2，1： | 1 |
| 12 | Computing Location Depth and Regression Depth in Higher Dimensions显示文摘 | Rousseeuw P J Struyf A | 1998 | Statistics and Computing1998，8，： | 1 |
| 13 | Unique regulation of CCL18 production by maturing dendritic cells显示文摘 | Vulcano M Struyf S Scapini P et a/ | 2003 | Journal of Immunology2003，170，7： | 1 |
| 14 | High- dimensional Computation of the Deepest Location显示文摘 | Struyf A Rousseeuw P J | 2000 | Computational Statistics & Data A- nalysis2000，34，4： | 1 |
| 15 | Chemokines in proliferative diabetic retinopathy and proliferative vitreorefinopathy显示文摘 | Abu Ei-Asrar A M Struyf S Kangave D | 2006 | Eur Cytokine Netw2006，17，3： | 1 |
| 16 | Computing location depth and regression depth in higher dimensions显示文摘 | Rousseeuw P J Struyf A | 1998 | Statistics and Computing1998，8，： | 1 |
| 17 | Eiffcient Computation of Location Depth Contours by Methouds of Computational Geometry显示文摘 | Miller K Ramaswami S Rousseeuw P Sellares J A Souvaine D Streinu I Struyf A | 2003 | Statistics and Computing2003，13，2： | 1 |
| 18 | High-dimensional computation of the deepest location显示文摘 | Struyf A and Rousseeuw P | 2000 | Computational Statistics and Data Analysis2000，34，： | 1 |
| 19 | High - dimensional Computation of the Deepest Location 显示文摘 | Struyf A Rousseeuw P J | 2000 | Computational Statistics and Data Analysis2000，34，： | 1 |
| 20 | The global biogeochemical silicon cycle显示文摘 | STRUYF E SMIS A DAMME S V | 2009 | Silicon2009，1，4： | 1 |
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