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| 1 | Influence of bio-inspired flow channel designs on the performance of a PEM fuel cell显示文摘Performance of the proton exchange membrane fuel cell(PEMFC)is appreciably affected by the channel geometry.The branching structure of a plant leaf and human lung is an efficient network to distribute the nutrients in the respective systems.The same nutrient transport system can be mimicked in the flow channel design of a PEMFC,to aid even reactant distribution and better water management.In this work,the effect of bio-inspired flow field designs such as lung and leaf channel design bipolar plates,on the performance of a PEMFC was examined experimentally at various operating conditions.A PEMFC of 49 cm2 area,with a Nafion 212 membrane with a 40%catalyst loading of 0.4 mg·cm-2 on the anode side and also 0.6 mg·cm-2 on the cathode side is assembled by incorporating the bio-inspired channel bipolar plate,and was tested on a programmable fuel-cell test station.The impact of the working parameters like reactants’relative humidity(RH),back pressure and fuel cell temperature on the performance of the fuel cell was examined;the operating pressure remains constant at 0.1 MPa.It was observed that the best performance was attained at a back pressure of 0.3 MPa,75°C operating temperature and 100%RH.The three flow channels were also compared at different operating pressures ranging from 0.1 MPa to 0.3 MPa,and the other parameters such as operating temperature,RH and back pressure were set as 75°C,100%and 0.3 MPa.The experimental outcomes of the PEMFC with bio-inspired channels were compared with the experimental results of a conventional triple serpentine flow field.It was observed that among the different flow channel designs considered,the leaf channel design gives the best output in terms of power density.Further,the experimental results of the leaf channel design were compared with those of the interdigitated leaf channel design.The PEMFC with the interdigitated leaf channel design was found to generate 6.72%more power density than the non-interdigitated leaf channel design.The fuel cell with interdigitated leaf channel design generated5.58%more net power density than the fuel cell with non-interdigitated leaf channel design after considering the parasitic losses. | Srinivasa Reddy Badduri G.Naga Srinivasulu S.Srinivasa Rao | 2020 | Chinese Journal of Chemical Engineering2020，28，3： | 6 |
| 2 | Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors显示文摘Novel therapies are urgently needed to improve global treatment of SARS-CoV-2 infection.Herein,we briefly provide a concise report on the medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors with representative examples in different strategies from the medicinal chemistry perspective. | Shenghua Gao Tianguang Huang Letian Song Shujing Xu Yusen Cheng Srinivasulu Cherukupalli Dongwei Kang Tong Zhao Lin Sun Jian Zhang Peng Zhan Xinyong Liu | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 5 |
| 3 | Insect classification and detection in field crops using modern machine learning techniques显示文摘The agriculture sector has an immense potential to improve the requirement of food and supplies healthy and nutritious food.Crop insect detection is a challenging task for farmers as a significant portion of the crops are damaged,and the quality is degraded due to the pest attack.Traditional insect identification has the drawback of requiring well-trained tax-onomists to identify insects based on morphological features accurately.Experiments were conducted for classification on nine and 24 insect classes of Wang and Xie dataset using the shape features and applying machine learning techniques such as artificial neural net-works(ANN),support vector machine(SVM),k-nearest neighbors(KNN),naive bayes(NB)and convolutional neural network(CNN)model.This paper presents the insect pest detec-tion algorithm that consists of foreground extraction and contour identification to detect the insects for Wang,Xie,Deng,and IP102 datasets in a highly complex background.The 9-fold cross-validation was applied to improve the performance of the classification mod-els.The highest classification rate of 91.5%and 90%was achieved for nine and 24 class insects using the CNN model.The detection performance was accomplished with less com-putation time for Wang,Xie,Deng,and IP102 datasets using insect pest detection algo-rithm.The comparison results with the state-of-the-art classification algorithms exhibited considerable improvement in classification accuracy,computation time perfor-mance while apply more efficiently in field crops to recognize the insects.The results of classification accuracy are used to recognize the crop insects in the early stages and reduce the time to enhance the crop yield and crop quality in agriculture. | Thenmozhi Kasinathan Dakshayani Singaraju Srinivasulu Reddy Uyyala | 2021 | Information Processing in Agriculture2021，8，3： | 4 |
| 4 | CeCl_3·7H_2O-SiO_2:Catalyst promoted microwave assisted neat synthesis,antifungal and antioxidant activities of α-diaminophosphonates显示文摘CeCl3 汃″ ??? 伲匭佩 ? ? 賥芉铦膌? ?? ? 諥?? 蒚郥邈 ? 鞊鳧? 貏 ? 钸 ? 楤浡湩灯潨灳潨慮整 ? 髧鞊 ? 隌觥? 諥¨ ?? 泔?? | Subba Rao Devineni Srinivasulu Doddaga Rajasekhar Donka Naga Raju Chamarthi | 2013 | Chinese Chemical Letters2013，24，8： | 3 |
| 5 | Contemporary medicinal chemistry strategies for the discovery and optimization of influenza inhibitors targeting vRNP constituent proteins显示文摘Influenza is an acute respiratory infectious disease caused by the influenza virus,affecting people globally and causing significant social and economic losses.Due to the inevitable limitations of vaccines and approved drugs,there is an urgent need to discover new anti-influenza drugs with different mechanisms.The viral ribonucleoprotein complex(vRNP)plays an essential role in the life cycle of influenza viruses,representing an attractive target for drug design.In recent years,the functional area of constituent proteins in vRNP are widely used as targets for drug discovery,especially the PA endonuclease active site,the RNA-binding site of PB1,the cap-binding site of PB2 and the nuclear export signal of NP protein.Encouragingly,the PA inhibitor baloxavir has been marketed in Japan and the United States,and several drug candidates have also entered clinical trials,such as favipiravir.This article reviews the compositions and functions of the influenza virus vRNP and the research progress on vRNP inhibitors,and discusses the representative drug discovery and optimization strategies pursued. | Lingxin Hou Ying Zhang Han Ju Srinivasulu Cherukupalli Ruifang Jia Jian Zhang Bing Huang Arianna Loregian Xinyong Liu Peng Zhan | 2022 | Acta Pharmaceutica Sinica B2022，12，4： | 2 |
| 6 | Construction of asm2 Deletion Mutant of Actinosynnema pretiosum and Medium Optimization for Ansamitocin P-3 Production Using Statistical Approach显示文摘 | Bandi Srinivasulu Yoonjung Kim Yongkeun Chang | 2006 | J Microbiol Biotechnol2006，16，9： | 1 |
| 7 | Optemisation studies on neomycin production by a mutant strain of Streptomyces marinensis in solid state fermentation显示文摘 | Ellaiah P Srinivasulu B Adinarayana K | 2004 | Process Biochemistry2004，39，： | 1 |
| 8 | Development of a weak-base docetaxe| derivative that can be loaded into lipid nanoparticles显示文摘 | Zhigaltsev IV Winters G Srinivasulu M | 2010 | J Control Release2010，144，3： | 1 |
| 9 | New potent cytotoxic lamellarin alkaloids from Indian ascidian Didemnum obscurum显示文摘 | Malla RS Srinivasulu M Satyanarayana N | 2005 | Tetrahedron Lett2005，9，61： | 1 |
| 10 | Evidence for Altered Numb Isoform Levels in Alzheimers Disease Patients and a Triple Transgenic Mouse Model显示文摘 | Srinivasulu Chigurupati Meenu Madan Eitan Okun Zelan Wei Jogi V. Pattisapu Mohamed R. Mughal Mark P. Mattson Sic L. Chan | 2011 | Journal of Alzheimers Disease2011，，： | 1 |
| 11 | Effect of substrate temperature on the physical properties of DC reactive magnetron sputtered ZnO films显示文摘 | Subramanyam T K Srinivasulu N B Uthanna S | 1999 | Optical Materials1999，13，2： | 1 |
| 12 | Synthesis of Benzocaine显示文摘 | Basa S Cand Srinivasulu C | 2003 | OPPISRIEFS2003，136，： | 1 |
| 13 | Structure and Microstructure of Ion-Plated Titanium Films显示文摘 | Gunasekhar K R Srinivasulu S Swarnalatha M | 1994 | Thin Solid Films1994，252，： | 1 |
| 14 | Chemopreventive and therapeutic modulation of green tea polyphenols on drug metabolizing enzymes in 4-Nitroquinoline 1-oxide induced oral cancer显示文摘 | Periasamy Srinivasan Subramaniyan Suchalatha Pon Velayutham Anandh Babu Rethinam Sundaresan Devi Shoba Narayan Kuruvimalai Ekambaram Sabitha Chennam Srinivasulu Shyamala Devi | 2008 | Chemico-Biological Interactions2008，，3： | 1 |
| 15 | Response surface methodological approach to optimize the nutritional parameters for neomycin production by Streptomyces marinensis under solid-state fermentation显示文摘 | ADINARAYANA K ELLAIAH P SRINIVASULU B | 2003 | Process Biochemistry2003，38，11： | 1 |
| 16 | Thermochemical analysis of venlafaxine hydrochloride polymorphs1-5 显示文摘 | Saikat R Srinivasulu A Ashwini N | 2005 | Crystal Growth & Design2005，5，6： | 1 |
| 17 | Optimal design of composite channels using genetic algorithm显示文摘 | Jain A Bhattacharjya R K Srinivasulu S | 2004 | Journal of Irrigation & Drainage Engineering2004，130，4： | 1 |
| 18 | Effect ofsubstrate temperature on the physical properties of DC reactivemagnetron sputtered ZnO films 显示文摘 | Subramanyam T K Srinivasulu N B Uthanna S | 1999 | Opt Mater1999，，13： | 1 |
| 19 | Kinetic and structural studies on thermal inactivation of lipoxygenase L1:effect of nonionic surfactants显示文摘 | Srinivasulu S Rao A G A | 1996 | J Agric Food Chem1996，44，11： | 1 |
| 20 | Influence of banana fibre chemical modification on the mechanical and morphological proper- ties of woven banana fabric/unsaturated polyester resin composites 显示文摘 | Hetal Shah B Srinivasulu Subhas C Shit | 2013 | Polymers from Renewable Resources2013，4，2： | 1 |
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