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| 1 | Endoscopic ultrasound-guided fiducial marker placement in pancreatic cancer:A systematic review and meta-analysis显示文摘BACKGROUND Pancreatic cancer(PC)mortality remains high despite advances in therapy.Combination chemoradiotherapy offers modest survival benefit over monotherapy with either.Fiducial markers serve as needed landmarks for imageguided radiotherapy(IGRT).Traditionally,these markers were placed surgically or percutaneously with limitations of each.Endoscopic ultrasound-guided placement overcomes these limitations.AIM To evaluate the safety,efficacy,and feasibility of endoscopic ultrasound(EUS)-guided fiducial placement for PC undergoing IGRT.METHODS Articles were searched in MEDLINE,PubMed,and Ovid journals.Pooling was conducted by fixed and random effects models.Heterogeneity was assessed using Cochran’s Q test based upon inverse variance weights.RESULTS Initial search identified 1024 reference articles for EUS-guided fiducial placement in PC.Of these,261 relevant articles were reviewed.Data was extracted from 11 studies(n=820)meeting inclusion criteria.Pooled proportion of successful placement was 96.27%(95%CI:95.35-97.81)with fiducial migration rates low at 4.33%(95%CI:2.45-6.71).Adverse event rates remained low,with overall pooled proportion of 4.85%(95%CI:3.04-7.03).CONCLUSION EUS-guided placement of fiducial markers for IGRT of PC is safe,feasible,and efficacious.The ability to target deep structures under direct visualization while remaining minimally invasive are added benefits.Moreover,the ability to perform fine needle aspiration or celiac plexus neurolysis add value and increase patient-care efficiency.Whether EUS-guided fiducial placement improves outcomes in IGRT or offers any mortality benefits over traditional placement remains unknown and future studies are needed. | Jaymon B Patel Vakya Revanur David G Forcione Matthew L Bechtold Srinivas R Puli | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，8： | 2 |
| 2 | Plumbagin induces reactive oxygen species which mediate apoptosis in human cervical cancer cells 显示文摘 | Srinivas P Gopinath G Banerji A | 2004 | Molecular Carcinogenesis2004，40，4： | 1 |
| 3 | New possible roles for aquaporin-4 in astrocytes: cell cytoskeleton and functional relation- ship with connexin43显示文摘 | NICCHIA G P SRINIVAS M LI W | 2005 | FASEB J2005，19，12： | 1 |
| 4 | Dyschromatosis universalis hereditaria 显示文摘 | Sethuraman G Srinivas CR D'Souza M | 2002 | Clin Exp Dermatol2002，27，6： | 1 |
| 5 | Iodotrimethylsi- lane-accelerated one-pot synthesis of 5-unsubstituted 3,4- dihydropyrimidin-2 (IH)-ones: a novel procedure for the Biginelli-like cycloeondensation reaction at room tempera- ture 显示文摘 | Sabitha G Reddy K B Srinivas R | 2005 | Heir Chim Acta2005，88，11： | 1 |
| 6 | Mixed oxide supported hydrodesulfurization eatalysts:A review显示文摘 | MURALI G SRINIVAS B N RANA M S | 2003 | Catalysis Today2003，86，14： | 1 |
| 7 | Emodin induces ap- optosis ofhuman cervical cancer cells through poly (ADP- ribose) polymerase cleavage and activation of caspase -9 显示文摘 | Srinivas G Anto R J srinivas P | 2003 | Eur J Pharmacol2003，473，223： | 1 |
| 8 | Intestinal obstruction due to Meckel's diverticulum a rare presentation 显示文摘 | SRINIVAS G N GULLEN P | 2007 | Acta Chir Belg2007，107，： | 1 |
| 9 | Effect of solution treatment temperature on the microstructure and tensile properties of P/M (HIP) processed superalloy Inconel 718 显示文摘 | APPA RAO G KUMAR M SRINIVAS M | 2003 | Journal of Material Science and Technology2003，，19： | 1 |
| 10 | Molecular organization in hydrotmpe assemblies显示文摘 | Srinivas V Rodley G A Raviktamr K Robinson W T Tumbull M M Balasubramanian D | 1997 | Langmuir1997，13，12： | 1 |
| 11 | Emodin induces apoptosis of human cervical cancer cells through poly (ADP-ribose) polymerase cleavage and activation of caspase-9 显示文摘 | Srinivas G Anto RJ Srinivas P | 2003 | Eur J Pharmacol2003，473，23： | 1 |
| 12 | Emodin induces apop tosis ofhuman cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9 显示文摘 | Srinivas G Anto RJ Srinivas P | 2003 | Eur J Pharmacol2003，473，223： | 1 |
| 13 | Emodin induces apoptosis of human cervical cancer cells through poly ( ADP - ribose) polymerase cleavage and activation of caspase - 9 显示文摘 | Srinivas G Anto R J Srinivas P | 2003 | Eur J Pharmacol2003，473，： | 1 |
| 14 | Pre-disaster invest- ment decisions for strengthening a highway network显示文摘 | SRINIVAS P F SIBEL S DILEK G | 2010 | Com- puters & Operations Research2010，37，： | 1 |
| 15 | Mixed oxide supported hydrodesulfurization catalysts : a review 显示文摘 | Dhar G M Srinivas B N Rana M S | 2003 | Catal Today2003，86，： | 1 |
| 16 | Dyschrom- atosis universalis hereditaria 显示文摘 | Sethuraman G Srinivas CR Thappa DM | 2002 | Clin Exp Dermatol2002，27，6： | 1 |
| 17 | Molecular mechanism of emodin action : transition from laxative ingredient to an antitumor agent显示文摘 | Srinivas G Babykutty S Sathiadevan PP | 2007 | Med Res Rev2007，27，： | 1 |
| 18 | Acute mesenteric venous thrombosis complicating endoscopic variceal sclerotherapy with absolute alcohol 显示文摘 | Ibrarullah M Wagholikar G Srinivas M | 2003 | Indian J Gastroenterol2003，22，1： | 1 |
| 19 | Mutant p53 protein, Bcl-2/Bax ratios and apoptosis in paediatric acute lymphoblastic leukaemia显示文摘 | Srinivas G Kusumakumary P Nair M K | 2000 | Cancer Res Clin Oncol2000，126，1： | 1 |
| 20 | A review of stimuli-responsive nanocarriers for drug and gene delivery显示文摘 | Srinivas G Harikrishna D Mansoor A | 2008 | J Controlled Release2008，126，3： | 1 |
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