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| 1 | Anti-inflammatory activity of Alpinia officinarum hance on rat colon inflammation and tissue damage in DSS induced acute and chronic colitis models显示文摘The purpose of this study was to investigate the possible prophylactic effects of Alpinia officinarum hance on experimentally induced acute and chronic colitis models,in-vivo and in-vitro.Acute and chronic colitis were induced in Male Wistar rats by administration of Dextran Sulfate Sodium(DSS)in drinking water.DSS induction exhibited colon shrinkage,increased the Disease Activity Index(DAI)score,increased the levels of inflammatory markers and caused severe anemia.DSS induced animals,co-treated with the hexane extract of Alpinia officinarum(HEAO)(200 mg/kg body wt),effectively suppressed colonic injury that was evidenced by the reduced DAI score,colon weight/length ratio,histological damage,proinflammatory markers and MPO activity.Further,it restored the colonic antioxidants near to normal levels by regulating the oxidative stress via attenuation of lipid peroxidation.Our results revealed that the degree of colitis caused by the administration of DSS was significantly attenuated by HEAO.In addition,the in-vitro study showed that HEAO treatment inhibited the proliferation of HT-29 cells and down regulated the mRNA expression of NF-B and COX-2.Taken together,these results suggest that HEAO is a promising anti-oxidant and anti-inflammatory agent that support its possible therapeutic role in the treatment of colitis. | Vijayabharathi Rajendiran Vidhya Natarajan Sivasithamparam Niranjali Devaraj | 2018 | Food Science and Human Wellness2018，7，4： | 5 |
| 2 | Chlamydospore germination and Fusarium wilt of banana plantlets in suppressive and conducive soils are affected by physical and chemical factors 显示文摘 | Peng H Sivasithamparam K Turner D | 1999 | Soil Biol Biochem1999，31，10： | 1 |
| 3 | Use of bacteriophage for the selective isolation of thermophilic actinomycetes from composted eucalyptus bark显示文摘 | KURTBOKE D I MURPHY N E SIVASITHAMPARAM K | 1993 | Canadian Journal of Microbiology1993，39，： | 1 |
| 4 | The infection processes of Sclerotinia sclerotiorum in cotyledon tissue of a re- sistant and a susceptible genotype of Brassica napus显示文摘 | Harsh Garg HuaLi Krishnapillai Sivasithamparam | 2010 | Annals of Botany2010，106，： | 1 |
| 5 | Effect of IAA on symbiotic germination of an Australian orchid and its production by orchid-associated bacteria显示文摘 | Wilkinson K G Dixon K W Sivasithamparam K | 1994 | Plant Soil1994，159，： | 1 |
| 6 | Non-streptomycete actino mycetes as biocontrol agents of soil-borne fungal plant patho- gens and as plant growth promoters 显示文摘 | El-Tarabily K Sivasithamparam K | 2006 | Soil Biology & Biochemistry2006，38，： | 1 |
| 7 | Inter-action of soil bacteria,mycorrhizal fungi and orchid seed in relation to germination of Australian orchids 显示文摘 | WILKINSON K G DIXON K W SIVASITHAMPARAM K | 1989 | New Phytologist1989，112，3： | 1 |
| 8 | Effect of IAA on symbiotic germination of an Australian orehid and its production by orchid-associated bacteria 显示文摘 | WILKINSON K G DIXON K W SIVASITHAMPARAM K | 1994 | Plant and Soil1994，159，2： | 1 |
| 9 | Scarification and environmental factors that enhance carpogenic germi- nation of sclerotia of Sclerotinia sclerotiorum 显示文摘 | Garg H Sivasithamparam K Barbetti M J | 2010 | Plant Disease2010，94，： | 1 |
| 10 | Non-streptomycete actinomycetes as biocontrol agents of soil-borne fungal plant pathogens and as plant growth promoters显示文摘 | El-Tarabily K A Sivasithamparam K | 2006 | Soil Biology & Biochemistry2006，38，： | 1 |
| 11 | Non - streptomy- cete actinomycetes as biocontrol agents of soil - borne fungal plant pathogens and as plant growth promoters 显示文摘 | E1 - Tarabily K A Sivasithamparam K | 2006 | Soil Biology and Biochemistry2006，38，7： | 1 |
| 12 | Trichoderma plant pathogen interactions 显示文摘 | Vinale F Sivasithamparam K Ghisalbcrti E L | 2008 | Soil Biology& Biochemistry2008，40，： | 1 |
| 13 | The infection processes of Sclerotinia sclerotiorum in cotyledon tissue of a resistant and a susceptible genotype of Brassica ha- pus 显示文摘 | Garg H Li H Sivasithamparam K | 2010 | Annals of Botany2010，106，6： | 1 |
| 14 | Potential of yeasts as biocontrol agents of soil-borne fungal plant pathogens and as plant growth promoters显示文摘 | EL-TARABILY K A SIVASITHAMPARAM K | | 0，，： | 1 |
| 15 | Chlamydospore germination and fusarium wilt of banana plantlets insuppressive and conducive soils are affected by physical and chemicalfactors显示文摘 | PENG H X SIVASITHAMPARAM K TURNER D W | 1999 | Soil Biology&Biochemistry1999，31，： | 1 |
| 16 | Internal transcribed spacer ribosomal DNA sequence of five species of Canoderma from Australia 显示文摘 | Smith B J Sivasithamparam K | 2000 | Mycol Res2000，104，： | 1 |
| 17 | The effect of soil compaction on the saprophytic growth of Rhizoc-tonia solani显示文摘 | Glenn O F Sivasithamparam K | 1990 | Plant and Soil1990，121，： | 1 |
| 18 | Benzoic acid may act as the functional group in salicylic acid and derivatives in the induction of multiple stress tolerance in plants显示文摘 | SENARATNA T MERRITT D DIXON K BUNN E TOUCHELL D SIVASITHAMPARAM K | 2003 | Plant Growth Regulation2003，39，： | 1 |
| 19 | Cross-pathogenicity of Rhizoctonia solani strains on pasture legumes in pasture-crop rotations 显示文摘 | YOU M P LANCASTER B Sivasithamparam K | 2008 | Plant and Soil2008，302，12： | 1 |
| 20 | Trichoderma-plant-pathogen interactions显示文摘 | VINALE F SIVASITHAMPARAM K GHISALBERTI E L | 2008 | Soil Biology and Bio- chemistry2008，40，1： | 1 |
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