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107篇 您的检索式:作者名="SHUAI Z"
    题名 作者 年代 出处 被引量
1^11C-PIBPET和^18F-FDGPET显像诊断阿尔茨海默病与遗忘型轻度认知损害的临床价值显示文摘目的应用11C-PIB PET和18F-FDG PET显像研究阿尔茨海默病和遗忘型轻度认知损害患者β-淀粉样蛋白(Aβ)沉积与葡萄糖代谢之间的关系,联合载脂蛋白E(ApoE)基因型进一步探讨遗忘型轻度认知损害与阿尔茨海默病的相关性。方法利用PET显像对阿尔茨海默病(14例)、遗忘型轻度认知损害(10例)和正常对照者(5例)脑组织Aβ沉积和葡萄糖代谢变化进行分析,采用聚合酶链反应-限制性片段长度多态性方法对ApoE基因型进行分析。结果阿尔茨海默病组患者11C-PIB标准化摄取比值在下顶叶、颞叶外侧、额叶、后扣带回皮质和楔前叶、枕叶和纹状体均高于正常对照组(P<0.05);遗忘型轻度认知损害组患者脑组织11C-PIB结合水平呈双峰形。11C-PIB+aMCI亚组与阿尔茨海默病组、11C-PIB-aMCI亚组与正常对照组之间11C-PIB标准化摄取比值差异均无统计学意义(P>0.05)。18F-FDG PET显像显示,3/5例11C-PIB+aMCI亚组患者双侧顶叶、颞叶和楔前叶代谢减低,其中2例ApoEε4等位基因携带者随访期间进展至阿尔茨海默病;3/5例11C-PIB-aMCI亚组患者双侧额叶和前扣带回代谢减低。结论11C-PIB PET显像是筛查具有阿尔茨海默病病理特点的遗忘型轻度认知损害患者的有效工具。具有阿尔茨海默病病理特征的遗忘型轻度认知损害患者可伴有顶叶、颞叶外侧皮质和楔前叶代谢减低,其中ApoEε4等位基因携带者更易进展至阿尔茨海默病痴呆。Shi Zhihong Wang Ying Liu Shuai Liu Shuling Z hou Yuying Wang Jinhuan Cai Li Gao Shuo Ji Yong 2014中国现代神经疾病杂志2014,14,3:8
2Self-evolution Neural Model 显示文摘Shuai J W Chen Z XI Liu R T 1996Physics Letters-A1996,221,5:1
3Combined system for harmonic suppression and reactive power compensa- tion显示文摘Luo A Shuai Z K Zhu W J 2009IEEE Transactions on Industry Electronics2009,56,2:1
4Identification of the function of extracellular polymeric substances(EPS)in denitrifying phosphorus removal sludge in the presence of copper ion显示文摘Wang Y Jian Q Shuai Z 2015Water Research2015,73,:1
5Polaron-pair binding due to interchain coupling in conjugated polymers显示文摘Shuai Z Br6das J L 1995Phys Rev B1995,52,13:1
6Thirty-Day Outcome of a Multicenter Registry Study of Stenting for Symptomatic Intracranial Artery Stenosis in China显示文摘Miao Z Zhang Y Shuai J 2015Stroke2015,46,10:1
7Optimization problems for general simple population with n-impulsive harvest显示文摘Shuai Z Liu B Wang K 2007J Math Anal Appl2007,329,1:1
8Functionalization of multiwalled carbon nanotubes with thermo-responsive azide-terminated poly(N-isopropylacrylamide) via click reactions显示文摘Su X Shuai Y Guo Z R 2013Molecules2013,18,4:1
9显示文摘Shuai Z Br das J L 1991Phys Rev B1991,44,11:1
10Identifieation of drought - responsive and novel populus triehoearpa microRNAs by high - throughput sequencing and their targets using degradome analysis 显示文摘Shuai P Liang D Zhang Z J 2013BMC Genomics2013,14,6:1
11Design eonsiderations for maintaining DC-side voltage of hybrid active power fiher with injection circuit显示文摘LUO An SHUAI Zhikang SHEN Z J 2009IEEE Transactions on Power Electronics2009,24,1:1
12显示文摘Shuai Z Beljonne D Br das J L 1992J Chem Phys1992,97,2:1
13显示文摘WANG LJ H Q K SHUAI Z 2007J Chem Phys2007,127,04:1
14Thermal and chemical reaction performance analyses of steam methane reforming in porous media solar thermochemical reactor 显示文摘WANG F SHUAI Y WANG Z 2014International Journal of Hydrogen Energy2014,39,2:1
15Combined system for harmonic suppression and reactive power compensation显示文摘Luo A Shuai Z Zhu W 0,,02:1
16Self-evolution neural model显示文摘SHUAI J W CHEN Z X LIU R T 1996Physics Letters-A1996,221,5:1
17Subchronic toxicity study of the total flavonoids from Rosa laevigata Michx fruit in rats 显示文摘Shuai Z G Zheng L L Xu L N 2012Regulatory Toxicology and Pharmacology2012,62,2:1
18Clofibrate induces heme oxy- genase 1 expression through a PPARu - independent mechanism in human cancer cells 显示文摘Shuai W Bethany NH Jundong Z 2013Cell Physiol Bioehem2013,32,5:1
19显示文摘Ye A Shuai Z Br das J L 2002Phys Rev B2002,65,04:1
20Evaluation of charge mobility in organic materials: From localized to delocal- ized descriptions at a First-Principles level显示文摘Shuai Z G Wang L J Li Q K 2011Advanced Materials2011,23,9:1
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