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	题名	作者	年代	出处	被引量
1	Differential reactivity of mouse monoclonal anti-HBs antibodies with recombinant mutant HBs antigens显示文摘AIM: To investigate the reactivity of a panel of 8 mouse anti-hepatitis B surface antigen (HBsAg) monoclonal antibodies (mAbs) using a collection of 9 recombinant HBsAg mutants with a variety of amino acid substitutions mostly located within the “a” region.METHODS: The entire HBs genes previously cloned into a mammalian expression vector were transiently transfected into COS7 cells. Two standard unmutated sequences of the ayw and adw subtypes served as controls. Secreted mutant proteins were collected and measured by three commercial diagnostic immunoassays to assess transfection efficiency. Reactivity of anti-HBs mAbs with mutated HBsAgs was determined by sandwich enzyme-linked immunosorbent assay (ELISA).RESULTS: Reactivity of anti-HBs mAbs with mutated HBsAgs revealed different patterns. While three mutants reacted strongly with all mAbs, two mutants reacted weakly with only two mAbs and the remaining proteins displayed variable degrees of reactivity towards different mAbs. Accordingly, four groups of mAbs with different but overlapping reactivity patterns could be envisaged. One group consisting of two mAbs (37C5-S7 and 35C6-S11) was found to recognize stable linear epitopes conserved in all mutants. Mutations outside the “a” determinant at positions 120 (P→S), 123(T→N) and 161(M→T) were found to affect reactivity of these mAbs.CONCLUSION: Our findings could have important implications for biophysical studies, vaccination strategies and immunotherapy of hepatitis B virus (HBV) mutants.	Azam Roohi Yaghoub Yazdani Jalal Khoshnoodi Seyed Mohammad Jazayeri William F Carman Mahmood Chamankhah Manley Rashedan Fazel Shokri	2006	World Journal of Gastroenterology2006，12，33：	4
2	Kinetics of murinedecidual dendritic cells显示文摘	Zarnani AH Moazzeni SM Shokri F	2007	Reproduction2007，133，1：	1
3	Production and characterization of mouse monoelonal antibodies recognizing human pan-IgG specific eonformational or linear epitopes 显示文摘	Hajighasemi F Khoshnoodi J Shokri F	2012	Avicenna J Med Biotechnol2012，4，4：	1
4	Diagnosis of simulated condylar bone defects using panoramic radiography,spiral tomography and cone-beam computed tomography:A comparison study显示文摘	Salemi F Shokri A Mortazavi H	2015	J Clin Exp Dent2015，7，1：	1
5	Thyromental height: a new clinical test for prediction of difficult laryngoscopy 显示文摘	Etezadi F Ahangari A Shokri H	2013	Anesth Analg2013，117，6：	1
6	Low dose revaccination in- duces robust protective anti-HBs antibody response in the majority of healthy non-responder neonates 显示文摘	Jafarzadeh A Zarei S Shokri F	2008	Vaccine2008，26，2：	1
7	Immunologic basis and immuno- prophylaxis of RhD induced hemolytic disease of the newborn (HDN) 显示文摘	Payam Khaja Pasha R Shokri F	2008	Iran J Immunol2008，5，4：	1
8	Production and characterization of mouse monoclonal antibodies recognizing human Pan-IgG specific conformational or linear epitopes 显示文摘	Hajighasemi F Khoshnoodi J Shokri F	2012	Avicenna J Med Biotechnol2012，4，4：	1
9	Immunologic basis andimmunoprophylaxis of RhD induced hemolytic disease ofthe newborn(HDN)显示文摘	Payam Khaja Pasha R Shokri F	2008	Iran J Immunol2008，5，4：	1
10	Immunologic basis and immunopro phylaxis of RhD induced hemolytic disease of the new- born (HDN)显示文摘	Pasha R Shokri F	2008	Iran J Immunol2008，5，4：	1
11	The antibody response to HBs antigen is regulated by coontinated Th1 and Th2 cytokine production in healthy neonates显示文摘	Jafarzadeh A Shokri F	2003	Clin Exp Immunol2003，131，3：	1
12	The antibody response to HBs antigen is regulated by coordinated Thl amd Th2 cytokine production in healthy nenates显示文摘	Jafarzadeh A Shokri F		0，，03：	1
13	Kinetics of murinedecidual dendritic cells 显示文摘	Zarnani AH Moazzeni SM Shokri F	2007	Reproduction2007，133，1：	1
14	Thyromental height:A new clinical test for prediction of difficult laryngoscopy显示文摘	Etezadi F Ahangari A Shokri H	2013	Anesthesia & Analgesia2013，117，6：	1
15	Diminished Th1 and Th2 cytokine production in healthy adult nonresponders to recombinant hepatitis B vaccine显示文摘	KARDAR G A JEDDI-TEHRANI M SHOKRI F	2002	Scand J Immunol2002，55，3：	1
16	ponders and nonresponders to recombinant hepatitisB vaccine 显示文摘	Soroosh P Shokri F Azizi M Analysis of T-cell receptor betachain variable gene segment usage in healthy adult re	2003	Scand J Immunol2003，57，5：	1
17	Establishment of human heterohybridoma and lymphoblastoid cell lines specific for the Rh D and C antigens显示文摘	Pasha RP ROOhi A Shokri F	2003	Transfus Med2003，13，2：	1
18	Low dose revaccination induces robust protective anti-HBs antibody response in the majority of healthy non-responder neonates 显示文摘	Jafarzadeh A Zarei S Shokri F	2008	Vaccine2008，26，2：	1
19	Overexpression of orphan receptor tyrosine kinase Rorl as a putative tumor-associated antigen in Iranian patients with acute lymphoblastic leukemia 显示文摘	Shabani M Asgarian-Omran H Jeddi-Tehrani M Vossou- gh P Faranoush M Sharifian RA Toughe GR Kordma- hin M Khoshnoodi J Roohi A Tavoosi N Mellstedt H Rabbani H Shokri F	2007	Tumour Biol2007，28，6：	1
20	Thyromental height: anew clinical test for prediction of difficult laryngoscopy显示文摘	Etezadi F Ahangari A Shokri H	2013	AnesthAnalgesia2013，117，6：	1

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