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| 1 | Alternatives for large-scale production of cultured beef: A review显示文摘Cultured beef is a method where stem cells from skeletal muscle of cows are cultured in vitro to gain edible muscle tissue. For large-scale production of cultured beef, the culture technique needs to become more efficient than today's 2-dimensional(2D) standard technique that was used to make the first cultured hamburger. Options for efficient large-scale production of stem cells are to culture cells on microcarriers, either in suspension or in a packed bed bioreactor, or to culture aggregated cells in suspension. We discuss the pros and cons of these systems as well as the possibilities to use the systems for tissue culture. Either of the production systems needs to be optimized to achieve an efficient production of cultured beef. It is anticipated that the optimization of large-scale cell culture as performed for other stem cells can be translated into successful protocols for bovine satellite cells resulting in resource and cost efficient cultured beef. | Matilda S M Moritz Sanne E L Verbruggen Mark J Post | 2015 | Journal of Integrative Agriculture2015，14，2： | 7 |
| 2 | Pancreatitis and pancreatic cancer:A case of the chicken or the egg显示文摘Acute pancreatitis(AP),chronic pancreatitis(CP)and pancreatic cancer are three distinct pancreatic diseases with different prognoses and treatment options.However,it may be difficult to differentiate between benign and malignant disease.AP may be a first symptom of pancreatic cancer,particularly in patients between the ages of 56 and 75 with presumed idiopathic AP who had a concomitant diagnosis of new-onset diabetes mellitus or patients who present with CP at diagnosis of AP.In these patients,additional imaging is warranted,preferably by endoscopic ultrasonography.CP may lead to pancreatic cancer through oncogenic mutations,mostly in patients with hereditary CP,and in patients in whom risk factors for pancreatic cancer(e.g.,nicotine and alcohol abuse)are also present.Patients with PRSS1-mediated CP and patients with a history of autosomal dominant hereditary CP without known genetic mutations may be considered for surveillance for pancreatic cancer.Pancreatic inflammation may mimic pancreatic cancer by appearing as a focal mass-forming lesion on imaging.Differentiation between the above mentioned benign and malignant disease may be facilitated by specific features like the duct-penetrating sign and the duct-to-parenchyma ratio.Research efforts are aimed towards developing a superior discriminant between pancreatitis and pancreatic cancer in the form of imaging modalities or biomarkers.This may aid clinicians in timely diagnosing pancreatic cancer in a potentially curable stage. | Devica S Umans Sanne A Hoogenboom Noor J Sissingh Selma J Lekkerkerker Robert C Verdonk Jeanin E van Hooft | 2021 | World Journal of Gastroenterology2021，27，23： | 5 |
| 3 | Antimicrobial drug-resistant Escherichia coli from humans and poultry products, minnesota and wisconsin,2002-2004 显示文摘 | JOHNSON J R SANNES M R CROY C | 2007 | Emerg Infect Dis2007，13，6： | 1 |
| 4 | Recombination resulting in vindence shift in avian influenza outbreak, Chile显示文摘 | Suarez D L Sanne D A Banks J | 2004 | Emerg Infect Dis2004，10，4： | 1 |
| 5 | Growth behavior of number distributed adherent MDCK cells for optimization in microcarrier cultures 显示文摘 | Bock A Sann H Schulze-Horsel J | 2009 | Biotechnology Progress2009，25，6： | 1 |
| 6 | A comprehensive study on the cell chemistry of the sodium superoxide (NaOz) battery显示文摘 | Hartmann P Bender C L Sann J | 2013 | Physical Chemistry Chemical Physics2013，15，11： | 1 |
| 7 | Effect of impurities on the matrix-assisted laser desorption mass spectra of single-stranded oligodeoxynucleotides 显示文摘 | SHALER T A WICKHAM J N SANNES K A | 1996 | Anal Chem1996，68，3： | 1 |
| 8 | Acceptor doping in ZnO with group-Ⅰ elements显示文摘 | Sann J Hofstaetter A Pfishterer D | 2006 | Phys Status Solidi(C)2006，3，4： | 1 |
| 9 | Antimicrobial drugresistant Escherichia coli from humans and poultry products, Minnesota and Wisconsin, 2002-2004显示文摘 | Johnson J R Sannes M R Croy C | 2007 | Emerg Infect Dis2007，13，6： | 1 |
| 10 | Severe hepatotoxicity associated with nevirapine use in HIV - infected subjects显示文摘 | Sanne I Mommeja Matin H Hinkle J | 2005 | J Infect Dis2005，191，6： | 1 |
| 11 | Stable adaptive tracking of uncertainty systems using nonlinearly parameterized on-line approximators 显示文摘 | SANNE R M MEARS M J | 1992 | IEEE Transactions on Neural Networks1992，3，6： | 1 |
| 12 | Antimierobial drug-resistant Escherichia coli from humans and poultry products, Minnesota and Wisconsin, 2002 -- 2004 显示文摘 | JOHNSON J R SANNES M R CROY C | 2007 | Emerg Infect Dis2007，13，6： | 1 |
| 13 | Antimicrobial drug-resistant Escherichia coli from humans and poultry products,Minnesota and Wisconsin,2002-2004显示文摘 | JOHNSON J R SANNES M R CROY C | 2007 | Emerg Infect Dis2007，13，6： | 1 |
| 14 | Antimicrobial drug -resist- ant Escherichia coli from humans and poultry products, Minnesota and Wisconsin, 2002 - 2004 显示文摘 | Johnson J R Sannes M R Cmy C | 2007 | Emerging Infectious Diseases2007，13，5： | 1 |
| 15 | Properties of-the oxygen vacancy in ZnO显示文摘 | HOFMANN D M PFISTERER D SANN J | 2007 | Applied Physics A: Materials Science & Processing2007，88，1： | 1 |
| 16 | Intrinsic and extrinsic point - defects in vapor transport grown ZnO bulk crystals 显示文摘 | Pfisterer D Hofmann D M Sann J Meyer B K Tena-Zaera R Munoz-Sanjose V Frank Th Pensl G | 2006 | Physica B2006，376，377： | 1 |
| 17 | Differential relationships in the association of the Big Five personality traits with positive mental health and psychopathology显示文摘 | Sanne M Lamers A Gerben J | 2012 | J Res Personality2012，46，： | 1 |
| 18 | Antimicrobial drug-resistant Escherichia coli from humans and poultry products,Minnesota and Wisconsin,2002-2004显示文摘 | Johnson J R Sannes M R Croy C | 2007 | Emerg Infect Dis2007，13，6： | 1 |
| 19 | VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials显示文摘 | Diether Lambrechts Bart Claes Paul Delmar Joke Reumers Massimiliano Mazzone Betül T Yesilyurt Roland Devlieger Chris Verslype Sabine Tejpar Hans Wildiers Sanne de Haas Peter Carmeliet Stefan J Scherer Eric Van Cutsem | 2012 | Lancet Oncology2012，，7： | 1 |
| 20 | Antiplatelet therapy in aneurysmal subarachnoid hemorrhage显示文摘 | SANNE M GABRIEL J E JEANNETTE W | 2003 | Stroke2003，，34： | 1 |
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