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| 1 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019，6，3： | 15 |
| 2 | The effect of noncontact, low-intensity, low-frequency, therapeutic ultrasound on lower extremity chronic wound pain, A retrospective chart review 显示文摘 | GEHLING M L SAMIES J H | 2007 | Ostomy Wound Management2007，53，3： | 1 |
| 3 | Rectification of the background potassium current : a determinant of rotor dynamics in ventricular fibrillation 显示文摘 | SAMIE F H BERENFELD O ANUMONWO J | 2001 | Circ Res2001，89，12： | 1 |
| 4 | Multiple Shear Key Connections for Preeast Shear Wall Panels显示文摘 | RIZKALLA Sami H SERRETTE Reynaud L HEUVEL J Scott | 1989 | PCI Journal1989，34，2： | 1 |
| 5 | Foreign ownership and information asymmetry显示文摘 | Choi J 1 Lam K K Sami H | 2013 | Asia-Pacific Journal of Financial Studies2013，42，2： | 1 |
| 6 | Microstructure dependent switching properties of VO2 thin films 显示文摘 | J'YRKI L SANTrU H SAMI S | 2008 | Sensors and Actuators: A2008，142，1： | 1 |
| 7 | Auditor Attestation under SOX Section 404 and EarniugsInfonnativeness 显示文摘 | Chen L H Krishnan J Sami H | 2013 | Auditing: A Journal of Prac- tice & Theory2013，32，1： | 1 |
| 8 | Goodwill Impairment Charges and Analyst Forecast Properties 显示文摘 | Chen L H Krishnan J Sami H | 2015 | Accounting Hori- zon2015，29，1： | 1 |
| 9 | Equation of state of NaCl: ultrasonicmeasurements to 8kbar and 800C and static lattice theory显示文摘 | Spetzler H Samis C G Connell R J | 1972 | J Phys Chem Sol1972，33，： | 1 |
| 10 | A class of proportional-integral sliding mode control with application to active suspension system显示文摘 | SamY M Osman J H S Ghani M R A | 2004 | Systems Control Lett2004，51，34： | 1 |
| 11 | Long-term effect of wastewater irrigation of forage crops on soil and plant quality parameters 显示文摘 | Munir J Mohammad R Sami H | 2007 | Desalination2007，215，13： | 1 |
| 12 | Effect of Supplemental Enzyme on Nutrient Digestibility and Performance of Broiler Chieks Fed on Diets Containing Triticale显示文摘 | Pourreza J Samie A H Rowghani E | 2007 | International Journal of Poultry Science2007，6，2： | 1 |
| 13 | Does the Provision of Non-audit Services Affect Investor Perceptions of Auditor Independence? 显示文摘 | Krishnan J Sami H Zhang Y | 2005 | Auditing: A Journal of Practice &Theory2005，24，2： | 1 |
| 14 | Performance characteristics of lithium vanadium phosphate as a cathode material for lithium-ion batteries 显示文摘 | SaMi M Y Barker J Huang H | 2003 | J Power Sources2003，，： | 1 |
| 15 | Auditor Attestation un- der SOX Section 404 and Earnings Informativeness显示文摘 | Chen L H Krishnan J Sami H | 2013 | Au- diting- A Journal of Practice & Theory2013，32，1： | 1 |
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