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| 1 | BCLC策略:预后预测和治疗推荐2022版更新显示文摘2018版BCLC预后和治疗推荐策略发布后,肝细胞癌(简称HCC)的研究又取得了重大进展。本次更新基于肝癌各领域的研究进展结果。重点关注影响策略的重要研究进展。虽然近年的研究结果成绩斐然,但将其引入为临床医生和研究者提供行动依据的循证模型指南来说证据效力依然不够确切。本文对该问题进行分析,阐述了为HCC患者制定个体化治疗临床决策所需的批判性思维和专业知识。 | Reig M Forner A Rimola J Ferrer-Fabrega J Burrel M Garcia-Criado A Kelley RK Galle PR Mazzaferro V Salem R Sangro B Singal AG Vogel A Fuster J Ayuso C Bruix J 刘永凡(摘译) 崔笑(摘译) 耿小平(审校) | 2022 | 肝胆外科杂志2022，30，5： | 80 |
| 2 | Role of live microbial feed supplements with reference to anaerobic fungi in ruminant productivity: A review显示文摘To keep the concept of a safe food supply to the consumers, animal feed industries world over are showing an increasing interest in the direct-fed microbials(DFM) for improved animal performance in terms of growth or productivity. This becomes all the more essential in a situation, where a number of the residues of antibiotics and/or other growth stimulants reach in milk and meat with a number of associated potential risks for the consumers. Hence, in the absence of growth stimulants, a positive manipulation of the rumen microbial ecosystem to enhance the feedstuff utilization for improved production efficiency by ruminants has become of much interest to the researchers and entrepreneurs. A few genera of live microbes(i.e., bacteria, fungi and yeasts in different types of formulations from paste to powder) are infrequently used as DFM for the domestic ruminants. These DFM products are live microbial feed supplements containing naturally occurring microbes in the rumen. Among different DFM possibilities, anaerobic rumen fungi(ARF) based additives have been found to improve ruminant productivity consistently during feeding trials. Administration of ARF during the few trials conducted, led to the increased weight gain, milk production, and total tract digestibility of feed components in ruminants. Anaerobic fungi in the rumen display very strong cell-wall degrading cellulolytic and xylanolytic activities through rhizoid development, resulting in the physical disruption of feed structure paving the way for bacterial action. Significant improvements in the fiber digestibility were found to coincide with increases in ARF in the rumen indicating their role. Most of the researches based on DFM have indicated a positive response in nutrient digestion and methane reducing potential during in vivo and/or in vitro supplementation of ARF as DFM. Therefore, DFM especially ARF will gain popularity but it is necessary that all the strains are thoroughly studied for their beneficial properties to have a confirmed ‘generally regarded as safe' status for ruminants. | Anil K Puniya Abdelfattah Z M Salem Sanjay Kumar Sumit S Dagar Gareth W Griffith Monica Puniya Sreenivas R Ravella Nikhil Kumar Tejpal Dhewa Ravinder Kumar | 2015 | Journal of Integrative Agriculture2015，14，3： | 17 |
| 3 | Evolution in the treatment of metastatic colorectal carcinoma of the liver显示文摘变形颜色没有治疗,到肝的表面的癌症与一致差的预后被联系。在在过去的十年的治疗的进展现在允许肝的外科的切除术与低病态和死亡发生。在化疗政体的改进有技术改进和现在允许病人的一个新组为外科的切除术变得合格的 paralleled。这章将在变形颜色在外科、化学疗法的政体考察最近的进展表面的癌症到肝。 | Charlotte E Ariyan Ronald R Salem | 2006 | World Journal of Gastroenterology2006，12，20： | 9 |
| 4 | Resection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies显示文摘BACKGROUND Recurrent acute pancreatitis(RAP)may be a presenting feature of and an indication for resection of pancreatic cysts,including intra-ductal papillary mucinous neoplasm(IPMN).Few data are available regarding the prevalence of malignancy and post-operative RAP in this population.AIM To study the role of resection to help prevent RAP and analyze if presentation as RAP would be a predictor for malignancy.METHODS This retrospective study assessed 172 patients who underwent surgical resection of pancreatic cystic neoplasms at a university hospital between 2002 and 2016.The prevalence of preoperative high-risk cyst features,and of neoplasia was compared between patients with and without RAP.To identify the cause of pancreatitis,all the patients had a detailed history of alcohol,smoking,medications obtained,and had cross-sectional imaging(contrast-enhanced computed tomography/magnetic resonance imaging)and endoscopic ultrasound to look for gallstone etiology and other structural causes for pancreatitis.The incidence of RAP post-resection was the primary outcome.RESULTS IPMN accounted for 101 cases(58.7%){[branch duct(BD)59(34.3%),main duct(MD)42](24.4%)}.Twenty-nine(16.9%)presented with RAP(mean 2.2 episodes):15 had BD-IPMN,8 MD-IPMN,5 mucinous cystic neoplasm and 1 serous cystic neoplasm.Malignancy was similar among those with vs without RAP for all patients[6/29(20.7%)vs 24/143(16.8%)]and IPMN patients[6/23(26.1%)vs 23/78(29.5%)],although tended to be higher with RAP in BD-IPMN,[5/15(33.3%)vs 3/44(6.8%),P=0.04].At mean follow-up of 7.2 years,1(3.4%)RAP patient had post-resection RAP.The mean episodes of acute pancreatitis before vs after surgery were 3.4 vs 0.02(P<0.0001).CONCLUSION Malignancy was not increased in patients with pancreatic cystic neoplasms who have RAP compared to those without RAP.In addition,specific cyst characteristics were not clearly associated with RAP.The incidence of RAP was markedly decreased in almost all patients following cyst resection. | Thiruvengadam Muniraj Harry R Aslanian Loren Laine Priya A Jamidar James F Farrell Kisha A Mitchell Ronald R Salem | 2021 | World Journal of Gastroenterology2021，27，15： | 3 |
| 5 | Chromogranin A polymor- phisms are associated with hypertensive renal disease显示文摘 | Salem R M Cadman P E Chen Y | 2008 | J Am Soc Nephrol2008，19，： | 1 |
| 6 | Resistance to freezing and thawing of recycled aggregate concrete 显示文摘 | Salem R M Burdette E G | 2003 | ACI Materials Journal2003，100，3： | 1 |
| 7 | High-Temperature Viscoelasticity and Heat-Setting of Poly (ethylene terephthalate) 显示文摘 | Buckley C P Salem D R | 1987 | Polymer1987，，28： | 1 |
| 8 | Transarterial chemoembolization and radioembolization显示文摘 | Sangro B Salem R | 2014 | Semin Liver Dis2014，34，4： | 1 |
| 9 | Diagenesis and reservoir quality evolution of palaeocene deep-water,marine sandstones,the Shetland-Faroes Basin,British continental shelf显示文摘 | Mansurbeg H Morad S Salem A Marfil R El-ghali M A K Nystuen J P Caja M A Amorosi A Garcia D A Iglesia La | 2008 | Marine and Petroleum Geology2008，25，： | 1 |
| 10 | The effects of diclofenac on cryo-indueed miosis 显示文摘 | al Salem M Hadidi H Alwash R | 1996 | Int Ophthalmol1996，20，： | 1 |
| 11 | Cyclohex-1-ene carboxylic acids:synthesis and biological evaluation of novel inhibitors of human 5α-reductase显示文摘 | Baston E Salem O Hartmann R W | 2003 | Arch Pharm Pharm Med Chem2003，1，： | 1 |
| 12 | Common charge-shift mutation Glu65Lys in K + channel beta(1)-Subunit KCNMB1:pleiotropic con-sequences for glomerular filtration rate and progressive renal disease 显示文摘 | Chen Y Salem R M Rao F | 2010 | Am J Nephrol2010，32，5： | 1 |
| 13 | Antimicrobial activity of carboxymethyl chitosan/polyethylene oxide nanofibers embedded silvel nanoparticles显示文摘 | Moustafa M G Fouda M R EI-Aassar Salem S AI-Deyab | 2013 | Carbohydrate Polymers2013，92，： | 1 |
| 14 | Resistance to freezing and thawing of recycled aggregate concrete 显示文摘 | Salem R M Burdette E G Jackson N M | 2003 | ACI Materials Journal2003，100，3： | 1 |
| 15 | Surgical outcome of pulmonary aspergilloma显示文摘 | BRIK A SALEM A M KAMAL A R | 2008 | Eur J Cardiothorac Surg2008，34，4： | 1 |
| 16 | Large scale association analysis for identification of genes under- lying premature coronary heart disease: cumulative per- spective from analysis of 111 candidate genes 显示文摘 | MCCARTHY J PARKER A SALEM R | 2004 | Journal of Medical Genetics2004，41，5： | 1 |
| 17 | Neutrophils pretreated with volatile anesthetics lose ability to cause cardiac dysfunc- tion显示文摘 | Hu G Vasiliauskas T Salem M R | 2003 | Anesthesiology2003，98，3： | 1 |
| 18 | Strain hardening due to deformation twinning in alpha-titanium: Mechanisms显示文摘 | Salem A A Kalidindi S R Doherty R D | 2006 | Metallurgical and Materials Transactions A2006，37，1： | 1 |
| 19 | Fibroblast growth factor-23 (FGF-23) is independently correlated to aortic calcification in baemodialysis patients显示文摘 | NASRALLAH M M EL-SHEHABY A R SALEM M M | 2010 | Nephrology Dialysis Transplantation: Official Publication of the European Dia|ysis and Transplant Association-European Renal Association2010，25，8： | 1 |
| 20 | Methodology for comparing two carrier phase tracking techniques显示文摘 | Salem D R Driscoll C O Lachapelle G | 2012 | GPS Solution2012，16，： | 1 |
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