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| 1 | Helicobacter pylori and autoimmune disease:Cause or bystander显示文摘Helicobacter pylori(H.pylori)is the main cause of chronic gastritis and a major risk factor for gastric cancer.This pathogen has also been considered a potential trigger of gastric autoimmunity,and in particular of autoimmune gastritis.However,a considerable number of reports have attempted to link H.pylori infection with the development of extra-gastrointestinal autoimmune disorders,affecting organs not immediately relevant to the stomach.This review discusses the current evidence in support or against the role of H.pylori as a potential trigger of autoimmune rheumatic and skin diseases,as well as organ specific autoimmune diseases.We discuss epidemiological,serological,immunological and experimental evidence associating this pathogen with autoimmune diseases.Although over one hundred autoimmune diseases have been investigated in relation to H.pylori,we discuss a select number of papers with a larger literature base,and include Sj grens syndrome,rheumatoid arthritis,systemic lupus erythematosus,vasculitides,autoimmune skin conditions,idiopathic thrombocytopenic purpura,autoimmune thyroid disease,multiple sclerosis,neuromyelitis optica and autoimmune liver diseases.Specific mention is given to those studies reporting an association of anti-H.pylori antibodies with the presence of autoimmune disease-specific clinical parameters,as well as those failing to find such associations.We also provide helpful hints for future research. | Daniel S Smyk Andreas L Koutsoumpas Maria G Myt-ilinaiou Eirini I Rigopoulou Lazaros I Sakkas Dimitrios P Bogdanos | 2014 | World Journal of Gastroenterology2014，20，3： | 12 |
| 2 | Antimicrobial re- sistance of major foodborne pathogens from major meat prod- uets显示文摘 | Gousia P Eeonomou V Sakkas H | 2011 | Foodb Pathog Dis2011，，8： | 1 |
| 3 | Endoscopic surgery of third ventricle lesions显示文摘 | Decq P Le GC Sakka L | 2000 | Neurochirurg2000，46，2： | 1 |
| 4 | Deregulation of the lysyl hydroxylase matrix cross-linking system in experimental and clinical bronchopulmonary dysplasia显示文摘 | Witsch TJ Turowski P Sakkas E | 2014 | Am J Physiol Lung Cell Mol Physiol2014，306，3： | 1 |
| 5 | Up-regulation of glucose metabolism during male pronucleus formation determines the early onset of the S phase in bovine zygote显示文摘 | Comizzoli P Urner F Sakkas D | 2006 | Biol Reprod2006，68，： | 1 |
| 6 | Heterogeneous photocatalytic degradation of the pharmaceutical agent salbutamol in aqueous titanium dioxide suspensions显示文摘 | Sakkas V A Calza P Medana C | 2007 | Applied Catalysis B:Environmental2007，77，1： | 1 |
| 7 | Induction of mani- a by rTMS:Report of two cases显示文摘 | Sakkas P Mihalopoulou P Mourtzouhou P | 2003 | Eur Psychiatry2003，18，19： | 1 |
| 8 | Bone quality:a reality for the process of osseointegration显示文摘 | Sakka S Coulthard P | | 0，，06： | 1 |
| 9 | Heterogeneous photocatalytic degradation of the pharmaceutical agent salbutamol in aqueous titanium dioxide suspensions 显示文摘 | Sakkas V A Calza P Medana C | 2007 | Applied Catalysis B: Environmental2007，77，12： | 1 |
| 10 | Endoscopic surgery of third ventricle lesions显示文摘 | Decq P Le Guerinel C Sakka L | 2000 | Neurochirurgie2000，46，3： | 1 |
| 11 | Induction of ma- nia by rTMS: report of two cases 显示文摘 | Sakkas P Mihalopoulou P Mourtzouhou P | 2003 | Eur Psychiatry2003，18，4： | 1 |
| 12 | L-carnitine modifies the humoral immune response in mice after in vitro or in vivo treatment显示文摘 | ATHANASSAKIS I MOURATIDOU M SAKKA P | 2001 | International Immunopharmacology2001，，1： | 1 |
| 13 | Implant failure: etiology and complications 显示文摘 | Sakka S Couthard P | 2011 | Med Oral Patol Oral Cir Bucal2011，16，1： | 1 |
| 14 | From oocyte to baby: a clinical evaluation of the biological efficiency of in vitro fertilization 显示文摘 | PATRIZIO P SAKKAS D | 2009 | Fertil Steril2009，91，4： | 1 |
| 15 | Repetitive transcranial magnetic stimulation (rTMS) in a patient suffering from comorbid depression and panic disorder following a myocardial infarction显示文摘 | Sakkas P Psarros C Papadimitriou GN | 2006 | Prog Neuropsychopharmacol Biol Psychiatry2006，30，： | 1 |
| 16 | Suicide gene therapy for cancer-current strategies 显示文摘 | ZAROGOULIDIS P DARWICHE K SAKKAS A | 2013 | J Genet Syndr Gene Ther2013，4，16： | 1 |
| 17 | Multivariate experimental design for the photocatalytic degradation of imipramine, determination of the reaction pathway and identification of intermediate products 显示文摘 | Calza P Sakkas V A Villioti A | 2008 | Appl Catal B Environ2008，84，34： | 1 |
| 18 | Bone quality: A reality for the process of osseointegration 显示文摘 | Sakka S Couhhard P | 2009 | Implant Dent2009，18，6： | 1 |
| 19 | Up-regulation of glucose metabolism during male pronucleus formation determines the early onset of the S phase in bovine zygote显示文摘 | Comizzoli P Urner F Sakkas D | 2003 | Biol Reprod2003，68，： | 1 |
| 20 | Photocatalytic degradation study of diclofenac over aqueous TiO2 suspensions显示文摘 | Calza P Sakkas V A Medana C | | 0，，： | 1 |
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