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| 1 | Computed morphometric analysis and expression of alpha fetoprotein in hepatocellular carcinoma and its related lesion显示文摘INTRODUCTION Hepatocellular carcinoma(HCC)is closely relatedwith hepatitis and cirrhosis.In order to investigatethe pathogenesis and early pathologic diagnosis ofHCC,HCC and related lesions were analyzedqualitively and quantitively by automatic imageanalysor and immunohistochemical assay. | Li Juan Shen Zong Ji Zhang Yang Ming Ou Hua Xian Zhang Run Huang Yun He Min Jie Wang Guo Shu Xu | 2000 | World Journal of Gastroenterology2000，6，3： | 11 |
| 2 | Relationship Between Coleoptile Length and Drought Resistance and Their QTL Mapping in Rice显示文摘By using a set of recombinant inbred line(RIL)population involving in 195 lines derived from a cross of Zhenshan 97B (lowland variety)and IRAT109(upland variety),the correlation analysis between coleoptile length(CL)and drought resistance index (DRI)and their QTL identification were conducted.There existed a significantly positive relationship between CL and DRI with the correlation coefficient of 0.2206**under water stress conditions.Under normal and water stress conditions,a total of eleven and four QTLs for CL and DRI,respectively,were detected on chromosomes 1,2,4,5,6,7,9,11 and 12 by using a linkage map including 213 SSR markers,which explained 4.84%to 22.65%of phenotypic variance.Chromosomes 1 and 9 possessing the QTLs for DRI harbored simultaneously QTLs for CL,and qCL9 shared the same chromosome location with qDRI9(RM160-RM215).Comparing the QTLs related to drought resistance in other studies,QTLs for CL and DRI were located in the same or adjacent marker interval as those related to root traits,such as number,dry weight,depth,and length of root.Moreover,sixteen and three pairs of epistatic loci for CL and DRI were found,which accounted for 56.17%and 11.93%of the total variation in CL and DRI,respectively. | HU Song-ping YANG Hua ZOU Gui-hua LIU Hong-yan LIU Guo-lan MEI Han-wei CAI Run LI Ming-shou LUO Li-jun | 2007 | Rice science2007，14，1： | 4 |
| 3 | Effect of CD86 blockage on the expressions of TGF-β1,MMP-9,TIMP-3 and PAI-1 proteins and outcome of pregnancy in murine abortion-prone model显示文摘In the present study, the effect of blockage of the costimulatory signal CD86 at time of implantation on the expressions of TGF-β1, MMP-9, TIMP-3 and PAI-1 proteins at the maternal-fetal interface and the outcome of pregnancy in murine abortion-prone model was investigated, in which the CBA/J x DBA/2 matings were used as the abortion-prone model and the CBA/J×BALB/c matings used as the normal pregnant model. The study was performed in following three groups: 2 groups of the abortion-prone model, which were experimental group and control experimental group, and 1 group of normal pregnant model, and each group had 10 pregnant CBA/J mice exclusively. Female pregnant CBA/J mice in the experimental group received an intraperitoneal (i. p.) injection of 100μg of antimouse CD86 mAb in 200μl of PBS at day 4.5 of gestation, and the irrelevant-isotope matched rat IgG2b was administrated in the control experimental group with the same dosage and at same time. For the normal pregnant group, no treatment was given. The pregnant CBA/J mice were killed on day 13.5 of gestation. Then, the embryo resorption rate was calculated and the expressions of TGF-β1, MMP-9, TIMP3 and PAI-1 were detected by using immunohistochemical methods. It was demonstrated that the embryo resorption rate in the experimental group was significantly reduced in comparison with that in the control experimental group (x2=7.441,P = 0.006), but there was no significant difference with that in normal pregnant group (x2=0.016, P = 0.898) . The expressions of TGF-β1 and PAI-1 in the experimental group were significantly increased in comparison with that in the control experimental group (P=0.010,P=0.003, respectively), with no significant difference from that in the normal pregnant group (P = 0.500) . However, the expression of MMP-9 in the experimental group was significantly reduced in comparison with that in the control experimental group (P = 0.012) with no significant difference from that in the normal pregnant group (P = 0.500) . The expression of TIMP-3 in the experimental group showed no significant difference both with the control experimental group (P = 0. 328) and the normal pregnant group (P = 0.500) . It is concluded that the blockage of the costimulatory molecule CD86 at early stage of gestation can render TGF-β1, MMP-9, TIMP-3 and PAI-1 proteins to express their immuno-tolerant effects through their characteristic pathways and induce the reduction of the embryo resorption rate in the natural abortion-prone model of mice to the level of normal pregnancy. | FU XI ZHAO YUAN YUAN ZHANG RUN HUA LIU SHUAN MING LI | 2006 | Journal of Microbiology and Immunology2006，4，2： | 3 |
| 4 | Pterostilbene Ameliorates Glycemic Control,Dyslipidemia and Liver Injury in Type 2 Diabetes Rats显示文摘Type 2 diabetes mellitus(T2DM)is typified by the increment of chronic blood glucose levels that is caused by an absolute and/or a relative deficiency of insulin,accounts for 90%of diabetes and causes a range of complications[1]. | ZHANG Yu Jing SUN Hua Lei WANG Teng LIU Xin Xin LIU Chang SHEN Fang WANG Bing Ya DING Run Rong LIU Yi Ming HUANG Guo Yu LI Wen Jie LI Xing | 2020 | Biomedical and Environmental Sciences2020，33，5： | 3 |
| 5 | Splenic littoral cell hemangioendothelioma: Report of a case with hepatic metastases and review of the literature显示文摘 | Ping He Xi‐De Yan Jin‐Rui Wang Run‐Cai Guo Hua‐Bin Zhang | 2014 | Ultrasound2014，，5： | 2 |
| 6 | Kinetic Characteristics of Neutralizing Antibody Responses Vary among Patients with COVID-19显示文摘Objective The coronavirus disease 2019(COVID-19) pandemic continues to present a major challenge to public health. Vaccine development requires an understanding of the kinetics of neutralizing antibody(NAb) responses to severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Methods In total, 605 serum samples from 125 COVID-19 patients(from January 1 to March 14, 2020)varying in age, sex, severity of symptoms, and presence of underlying diseases were collected, and antibody titers were measured using a micro-neutralization assay with wild-type SARS-CoV-2.Results NAbs were detectable approximately 10 days post-onset(dpo) of symptoms and peaked at approximately 20 dpo. The NAb levels were slightly higher in young males and severe cases, while no significant difference was observed for the other classifications. In follow-up cases, the NAb titer had increased or stabilized in 18 cases, whereas it had decreased in 26 cases, and in one case NAbs were undetectable at the end of our observation. Although a decreasing trend in NAb titer was observed in many cases, the NAb level was generally still protective.Conclusion We demonstrated that NAb levels vary among all categories of COVID-19 patients. Longterm studies are needed to determine the longevity and protective efficiency of NAbs induced by SARS-CoV-2. | LI Ling Hua TU Hong Wei LIANG Dan WEN Chun Yan LI An An LIN Wei Yin HU Ke Qi HONG Wen Shan LI Yue Ping SU Juan ZHAO San Tao LI Wei YUAN Run Yu ZHOU Ping Ping HU Feng Yu TANG Xiao Ping KE Chang Wen KE Bi Xia CAI Wei Ping | 2021 | Biomedical and Environmental Sciences2021，34，12： | 1 |
| 7 | Effects of exogenous putrescine on gas-exchange characteristics and chlorophyll fluorescence of NaCl-stressed cucumber seedlings显示文摘 | Run Hua Zhang Jun Li Shi Rong Guo Takafumi Tezuka | 2009 | Photosynthesis Research2009，，3： | 1 |
| 8 | Comparison of linear and nonlinear analysis in estimating the Thomas model parameters for methylene blue adsorption onto natural zeolite in fixed-bed eolumn显示文摘 | HAN Run Ping WANG Yi ZOU Wei Hua | 2007 | J Hazard Mater2007，145，12： | 1 |
| 9 | Plasma cell labeling index correlates with deletion of 13q14 in multiple myeloma显示文摘 | Chunming Li Lijuan Chen Xiao Gao Xiaoyan Qu Wenyi Shen Ruifang Yang Run Zhang Hairong Qiu Jiaren Xu Hua Lu Jianyong Li | 2011 | Leukemia & Lymphoma2011，，2： | 1 |
| 10 | Recent advances in quantum dot catalysts for hydrogen evolution:Synthesis,characterization,and photocatalytic application显示文摘Photocatalytic water splitting is beneficial for the effective mitigation of global energy and environmental crises.Owing to multi-exciton generation,impressive light harvesting,and excellent photochemical properties,the quantum dot(QD)-based catalysts reveal a considerable potential in photocatalytic hydrogen(H_(2))production compared with bulk competitors.In this review,we summarize the recent advances in QDs for photocatalytic H_(2) production by enumerating different synthetic and characterization strategies for QDs.Various QDs-based photocatalysts are introduced and summarized in categories,and the role of different QDs in varied systems,as well as the mechanism and key factors that enhance the photocatalytic H_(2) generation performance,is discussed.Finally,conclusions and future perspectives in the exploration of highly efficient QDs-based photocatalysts for innovative applications are highlighted. | Haiwei Su Weikang Wang Run Shi Hua Tang Lijuan Sun Lele Wang Qinqin Liu Tierui Zhang | 2023 | Carbon Energy2023，5，9： | 1 |
| 11 | Haploidentical hematopoietic stem cell transplantation following myeloablative conditioning regimens in hematologic diseases with G-CSF-mobilized peripheral blood stem cells grafts without T cell depletion: a single center report of 38 cases显示文摘 | Rui-Nan Lu Kou-Rong Miao Run Zhang Ming Hong Ji Xu Yu Zhu Hua-Yuan Zhu Xiao-Yan Qu Shuai Wang Li Wang Lei Fan Wen-Yi Shen Hua Lu Hong-Xia Qiu Xiao-Yan Zhang Li-Juan Chen Wei Xu Jian-Yong Li Han-Xin Wu Si-xuan Qian | 2014 | Medical Oncology2014，，8： | 1 |
| 12 | Effect of combined mutations in the enhancer II and basal core promoter of hepatitis B virus on development of hepatocellular carcinoma in Q idong, C hina显示文摘 | Li‐Shuai Qu Jing Zhu Tao‐Tao Liu Xi‐Zhong Shen Tao‐Yang Chen Zheng‐Pin Ni Run‐Zhou Ni Cui‐Hua Lu | 2014 | Hepatol Res2014，，12： | 1 |
| 13 | Increased serum vWF and sVCAM-1 levels are associated with late or very late angiographic stent thrombosis after sirolimus-eluting stent implantation显示文摘 | Cao Jin Lin Lu Zheng Bin Zhu Rui Yan Zhang Qi Zhang Run Du Feng Hua Ding Qiu Jing Chen Wei Feng Shen | 2010 | Coronary Artery Disease2010，，5： | 1 |
| 14 | Image encryption based on the multiple-order discrete fractional cosine transform 显示文摘 | WU Jiang - hua ZHANG Lin ZHOU Nan - run | 2010 | Optics Communications2010，283，2010： | 1 |
| 15 | Expression of FOXJ1 in hepatocellular carcinoma: Correlation with patients’ prognosis and tumor cell proliferation显示文摘 | Hong‐Wei Chen Xiao‐Dong Huang Hong‐Chen Li Song He Run‐Zhou Ni Cui‐Hua Chen Chen Peng Gang Wu Gui‐Hua Wang Ying‐Ying Wang Yun‐Hong Zhao Yi‐Xin Zhang Ai‐Guo Shen Hui‐Min Wang | 2013 | Mol. Carcinog2013，，8： | 1 |
| 16 | The Influence of Chlorine on the Migration Behavior of Alkali Metal during Biomass and Coal Co-Combustion显示文摘 | Yang Tian Hua Xing Wan Li Kai Xing Ping Li Run Dong He Ye Guang | 2011 | Applied Mechanics and Materials2011，，40： | 1 |
| 17 | Burst strain disturbance—A new test study on fracture precursor显示文摘IntroductionBeforeanearthquakeocuurs,deformationvariationsobviouslyappearinseismogenicareaandnearbywhichwerereportedalot.Earl... | ZHAO YONG XU 1) RUN HAI YANG 1) BIN WANG 1) JIN MING ZHAO 1) YU FENG YAO 1) PEI ZHONG HUA 1) SHI RONG MEI 2) 1) Seismological Bureau of Yunnan Province, Kunming, 650041, China 2) Center for Analysi | 1998 | Acta Seismologica Sinica(English Edition)1998，11，6： | 1 |
| 18 | Design of double freeform - surface lens for LED uniform illumination with min- imum Fresnel losses 显示文摘 | Run Hua Zhiqiang Gane Xiaobing Luoa | 2013 | Optik2013，，124： | 1 |
| 19 | Plasma cell labeling index correlates with deletion of 13q14 in multiple myeloma显示文摘 | Chunming Li Lijuan Chen Xiao Gao Xiaoyan Qu Wenyi Shen Ruifang Yang Run Zhang Hairong Qiu Jiaren Xu Hua Lu Jianyong Li | 2011 | Leukemia & Lymphoma2011，，2： | 1 |
| 20 | Characterizations of a Hypomorphic Argonaute1 Mutant Reveal Novel AGO1 Functions in Arabidopsis Lateral Organ Development显示文摘 | Li Yang Weihua Huang Hua Wang Run Cai Yuquan Xu Hai Huang | 2006 | Plant Molecular Biology (-)2006，，1： | 1 |
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