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| 1 | Novel treatment options for perforations of the upper gastrointestinal tract:Endoscopic vacuum therapy and over-the-scope clips显示文摘Endoscopic management of leakages and perforations of the upper gastrointestinal tract has gained great importance as it avoids the morbidity and mortality of surgical intervention.In the past years,covered selfexpanding metal stents were the mainstay of endoscopic therapy.However,two new techniques are now available that enlarge the possibilities of defect closure:endoscopic vacuum therapy(EVT),and over-the-scope clip(OTSC).EVT is performed by mounting a polyurethane sponge on a gastric tube and placing it into the leakage.Continuous suction is applied via the tube resulting in effective drainage of the cavity and the induction of wound healing,comparable to the application of vacuum therapy in cutaneous wounds.The system is changed every 3-5 d.The overall success rate of EVT in the literature ranges from 84%to 100%,with a mean of 90%;only few complications have been reported.OTSCs are loaded on a transparent cap which is mounted on the tip of a standard endoscope.By bringing the edges of the perforation into the cap,by suction or by dedicated devices,such as anchor or twin grasper,the OTSC can be placed to close the perforation.For acute endoscopy associated perforations,the mean success rate is 90%(range:70%-100%).For other types of perforations(postoperative,other chronic leaks and fistulas)success rates are somewhat lower(68%,and59%,respectively).Only few complications have been reported.Although first reports are promising,further studies are needed to define the exact role of EVT and OTSC in treatment algorithms of upper gastrointestinal perforations. | Rudolf Mennigen Norbert Senninger Mike G Laukoetter | 2014 | World Journal of Gastroenterology2014，20，24： | 25 |
| 2 | Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties显示文摘 | Sarah Schwitalla Alexander A. Fingerle Patrizia Cammareri Tim Nebelsiek Serkan I. G?ktuna Paul K. Ziegler Ozge Canli Jarom Heijmans David J. Huels Guenievre Moreaux Rudolf A. Rupec Markus Gerhard Roland Schmid Nick Barker Hans Clevers Roland Lang Jens Neu | 2013 | Cell2013，，： | 3 |
| 3 | Surgical treatment of hepatocellular carcinoma: Experience with liver resection and transplantation in 198 patients显示文摘 | Burckhardt Ringe M.D. Rudolf Pichlmayr M.D. Christian Wittekind M.D. Günter Tusch M.S | 1991 | World Journal of Surgery1991，，2： | 2 |
| 4 | Benign Liver Tumors: Differential Diagnosis and Indications for Surgery显示文摘 | Arved Weimann Burckhardt Ringe Jürgen Klempnauer Peter Lamesch Klaus F. Gratz Mathias Prokop Hansj?rg Maschek Günter Tusch Rudolf Pichlmayr | 1997 | World Journal of Surgery1997，，9： | 2 |
| 5 | Continuum percolation of wireless ad hoc communication networks 显示文摘 | Ingmar G Wolfram K Rudolf S | 2003 | Statistical Mechanics and its Applications2003，325，34： | 1 |
| 6 | Immunohistochemical localization of the small proteoglycans decorin and biglycan in human intervertebral discs显示文摘 | Werner G?tz Sabine Barnert Rudolf Bertagnoli Nicolai Miosge Hans Kresse Rainer Herken | 1997 | Cell & Tissue Research1997，，1： | 1 |
| 7 | Performance meas- urement of modular product platforms 显示文摘 | SCHUH G RUDOLF S VOGELS T | 2014 | Variety Man- agement in Manufacturing2014，17，： | 1 |
| 8 | A comparison between batch and fed-batch simultaneous saccharification and fermentation of steam pretreated spruce显示文摘 | Rudolf A Alkasrawi M Zacchi G | 2005 | Enzyme and Microbial Technology2005，37，2： | 1 |
| 9 | From Rolandic epilepsy to continuous spike and waves during sleep and Landau-Kleffner syndromes:insights into possible genetic factors显示文摘 | Rudolf G | | 0，，7： | 1 |
| 10 | Surgical treatment of hepatocellular carcinoma: Experience with liver resection and transplantation in 198 patients显示文摘 | Burckhardt Ringe M.D. Rudolf Pichlmayr M.D. Christian Wittekind M.D. Günter Tusch M.S | 1991 | World Journal of Surgery1991，，2： | 1 |
| 11 | A comparison between batch and fed-batch simultaneous saccharification and fermentation of steam pretreated spruce显示文摘 | Rudolf A Alkasrawi M Zacchi G | 2005 | Enzyme and Microbial Technology2005，37，2： | 1 |
| 12 | GRIN2A mutations in acquired epileptic aphasia and related childhood focal epilepsies and encephalopathies with speech and language dysfunction显示文摘 | Lesca G Rudolf G Bruneau N | 2013 | Nat Genet2013，45，9： | 1 |
| 13 | The value of the world's ecosystem services and natural capital显示文摘 | D'arge R Rudolf DE G | 1997 | Nature1997，387，： | 1 |
| 14 | A comparison between batch and fed-batch simultaneous saccharification and fermentation of steam pretreated spruee显示文摘 | Rudolf A Alkasrawi M Zacchi G | 2005 | Enzyme Mierob Technoi2005，37，： | 1 |
| 15 | The value of the world, secosystem Services and natural capita 显示文摘 | ] Costanza R D Aige R Rudolf D G | 1997 | Nature1997，387，： | 1 |
| 16 | Laparoscopic appendectomy显示文摘 | Arnold Pier Friedrich G?tz Christoph Bacher Rudolf Ibald | 1993 | World Journal of Surgery1993，，1： | 1 |
| 17 | Optimised antireflection coatings for planar silicon solar cells using remote PECVD silicon nitride and porous silicon dioxide显示文摘 | Henning Nagel Armin G Aberle Rudolf Hezel | 1999 | Prog Photovolt: Res Appl1999，7，： | 1 |
| 18 | Laboratory research polygenic control of idiopathic generalized epilepsy phenotypes in the genetic absence rats from strasbourg (GAERS) 显示文摘 | Rudolf G Bihoreau M Thérèse G | 2004 | Epilepsia2004，45，4： | 1 |
| 19 | The Value of theWorld’s Ecosystem Services and Natural Capital显示文摘 | Costanza R D Arge R Rudolf D G | 1998 | Eco-logical Economics1998，25，1： | 1 |
| 20 | New Ultradeformable Drug Carriers for Potential Transdermal Application of Interleukin-2 and Interferon-a Theoretic and Practical Aspects显示文摘 | Christian Hofer Rudolf Hartung Roland G?bel Petra Deering Antonie Lehmer Jürgen Breul | 2000 | World Journal of Surgery2000，，10： | 1 |
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