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您的检索式：作者名="Rudiger Simon"
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| 1 | Heterotopic bone formation in the musculus latissimus dorsi of sheep usingβ-tricalcium phosphate scaffolds:evaluation of different seeding techniques显示文摘Osseous reconstruction of large bone defects remains a challenge in oral and maxillofacial surgery.In addition to autogenous bone grafts,which despite potential donor-site mobility still represent the gold standard in reconstructive surgery,many studies have investigated less invasive alternatives such as in vitro cultivation techniques.This study compared different types of seeding techniques on pureβ-tricalcium phosphate scaffolds in terms of bone formation and ceramic resorption in vivo.Cylindrical scaffolds loaded with autologous cancellous bone,venous blood,bone marrow aspirate concentrate or extracorporeal in vitro cultivated bone marrow stromal cells were cultured in sheep on a perforator vessel of the musculus latissimus dorsi over a 6-month period.Histological and histomorphometric analyses revealed that scaffolds loaded with cancellous bone were superior at promoting heterotopic bone formation and ceramic degradation,with autogenous bone and bone marrow aspirate concentrate inducing in vivo formation of vital bone tissue.These results confirm that autologous bone constitutes the preferred source of osteoinductive and osteogenic material that can reliably induce heterotopic bone formation in vivo. | Simon Spalthoff Rudiger Zimmerer Jan Dittmann Horst Kokemuller Marco Tiede Laura Flohr Philippe Korn Nils-Claudius Gellrich Philipp Jehn | 2018 | Regenerative Biomaterials2018，5，2： | 3 |
| 2 | QT DISPERSION: A RISK INDICATOR FOR SEVERE VENTRICULAR ARRHYTHMIA IN PATIENTS WITH ISCHEMIC AND IDIOPATHIC CARDIOMYOPATHY显示文摘Increased QT dispersion in the surface ECG (QTd = QTmax minus QTmin) is considered as an indicator of electrical inhomogeneitv and a useful predictor for severe ventricular arrhythmia and sudden cardiac death in patients with different heart diseases. Patients with ischemic and idiopathic cardiomyopathy have a very high incidence of severe ventricular arrhythmia and sudden cardiac death. We compared QT, QTc. JT and JTc dispersion in ischemic (ICMP) and idopathic (CCMP) cardiomyopathy patients with and without severe ventricular arrhythmia and normal controls. | Fu Guosheng Achim MeiBner Rudiger Simon | 1995 | Chinese Medical Journal1995，，3： | 2 |
| 3 | The CLE40 and CRN/CLV2 Signaling Pathways Antagonistically Control Root Meristem Growth in Arabidopsis显示文摘在主要的根分裂组织的区别过程被被植物激素或由分泌的肽调整的几条发信号的小径控制。一个活跃的根分裂组织的长期的维护要求新干细胞的产生和从分裂组织的这些的损失精确由于区别被协调。经由 phenotypic 和异种的大规模 transcriptome 分析,我们证明发信号的肽 CLE40 和受体蛋白质 CLV2 和 CRN 在反对地在近似的根分裂组织调整房间区别的二条遗传上可分离的小径行动。CLE40 由在 abscisic 酸,植物生长素,并且细胞激动素发信号与角色控制基因在整个主要的根分裂组织禁止房间区别。CRN 和 CLV2 联合控制在近似的根分裂组织的转变地区明确地支持房间区别的目标基因。当 CRN 和 CLV2 不在在正常生长下面的发信号的小径调节的 CLE40 正在行动时,当 CLE40 或相关 CLE 肽的层次增加时,两蛋白质被要求。我们这里证明控制根分裂组织区别的二条反对地代理的小径能被一样的肽以一种剂量依赖者方式激活。 | Helge Pallakies Rudiger Simon | 2014 | Molecular Plant2014，7，11： | 1 |
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