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| 1 | Electrocardiographic markers of cardiac resynchronization therapy response:delayed time to intrinsicoid deflection onset in lateral leads显示文摘Cardiac resynchronization therapy(CRT)has emerged as an important intervention for patients with heart failure(HF)with reduced ejection fraction and delayed ventricular activation.In these patients,CRT has demonstrated to improve quality of life,promote reverse left ventricular(LV)remodeling,reduce HF hospitalizations,and extend survival.However,despite advancements in our understanding of CRT,a significant number of patients do not respond to this therapy.Several invasive and non-invasive parameters have been assessed to predict response to CRT,but the electrocardiogram(ECG)has remained as the prevailing screening method albeit with limitations.Ideally,an accurate,simple,and reproducible ECG marker or set of markers would dramatically overcome the current limitations.We describe the clinical utility of an old ECG parameter that can estimate ventricular activation delay:the onset to intrinsicoid deflection(ID).Based on the concept of direct measurement of ventricular activation time(intrinsic deflection onset),time to ID onset measures on the surface ECG the time that the electrical activation time takes to reach the area subtended by the corresponding surface ECG lead.Based on this principle,the time to ID on the lateral leads can estimate the delay activation to the lateral LV wall and can be used as a predictor for CRT response,particularly in patients with non-specific intraventricular conduction delay or in patients with left bundle branch block and QRS<150 ms.The aim of this review is to present the current evidence and potential use of this ECG parameter to estimate LV activation and predict CRT response. | Rubén KA Tapia-Orihuela S Michael Gharacholou Samuel J Asirvatham Freddy Del-Carpio Munoz | 2022 | Journal of Geriatric Cardiology2022，19，1： | 3 |
| 2 | Vehicle routing problem with uncertain demands:An advanced particle swarm algorithm显示文摘 | Babak F M Rubén R Seyed J S | 2011 | Computers Industrial Engineering2011，62，1： | 1 |
| 3 | Characterization of EST-SSR In loblolly pine and spruce显示文摘 | Bérubé Y Zhuang J Rungis D | 2007 | Tree Genetic s& Genomes2007，3，3： | 1 |
| 4 | Physicochemical characterization of diesel exhaust particles: Factors for assessing biological activity显示文摘 | Jones T P Williamson B J | 1999 | Atmospheric Environment1999，35，： | 1 |
| 5 | Effect of climate change on greenhouse gas emissions from arable crop rotations显示文摘 | J?rgen E. Olesen Gitte H. Rub?k Tove Heidmann S?ren Hansen Christen D. B?rgensen | 2004 | Nutrient Cycling in Agroecosystems2004，，2： | 1 |
| 6 | The interaction of guarantees, surplus distribution, and asset allocation in with profit life insurance policies显示文摘 | Kling A Richter A Rub J | 2007 | Insurance: Mathematics and Economics2007，40，1： | 1 |
| 7 | Physicochemical characterization of diesel exhaust particles:factors for assessing biological activity显示文摘 | BéruBé K A Jones T P Williamson B J | 1999 | Atmospheric Environment1999，33，10： | 1 |
| 8 | Effects of physio therapy on F-wave-amplitudes in spasticity显示文摘 | Rosche J Rub K Niemann Delius B | 1996 | Electromyogr Clin Neurophysiol1996，36，： | 1 |
| 9 | Robust simple sequence repeat markers for spruce (Picea spp.) from expressed sequence tags显示文摘 | Dainis Rungis Yanik Bérubé Jun Zhang Steven Ralph Carol E. Ritland Brian E. Ellis Carl Douglas J?rg Bohlmann Kermit Ritland | 2004 | Theoretical and Applied Genetics2004，，6： | 1 |
| 10 | Electrical Properties of Boron Nitride Matrix Composites: I, Analysis of McLachlan Equation and Modeling of the Conductivity of Boron Nitride - Boron Carbide and Boron Nitride-Silicon Carbide Composites 显示文摘 | Runyan J Gerhardt R A Rub R | 2001 | Journal of the American Ceramic Society2001，84，7： | 1 |
| 11 | Hydrogen peroxide modifies the kinetics of HERG channel expressed in a mammalian cell line显示文摘 | Bérubé J Caouette D Daleau P | | 0，，： | 1 |
| 12 | Analysis of vapor- liquid equilibrium of ethanol - water system via headspaee gas chromatography:effect of molecular sieves 显示文摘 | Banat F A Abu Al - Rub F A Simandl J | 2002 | Separation and Purification Technology2002，18，： | 1 |
| 13 | GMWB for Life: An Analysis of Lifelong Withdrawal Guarantees显示文摘 | Holz D Kling A Rub J | 2007 | Journal of Risk and In- surance2007，5，3： | 1 |
| 14 | A metaheuristic to solve the transmission expansion planning显示文摘 | RUB(E)N R MARCOS J R | 2007 | IEEE Transactions on Power Systems2007，22，4： | 1 |
| 15 | Physicochemical characterization of diesel exhaust particles:Factors for assessing biological activity显示文摘 | Bérubé K A Jones T P Williamson B J | 1999 | Atmospheric Environment1999，33，： | 1 |
| 16 | Complement Factor H Is a Serum-binding Protein for Adrenomedullin, and the Resulting Complex Modulates the Bioactivities of Both Partners显示文摘 | Rubén Pío Alfredo Martínez Edward J | 2001 | J Biol Chem2001，276，15： | 1 |
| 17 | 查看详情显示文摘 | Alarcon T P6rez Madrid A Rub'i J M | | 0，，： | 1 |
| 18 | Comparison of pre - reducing agents for antimony determination by hydride generation atomic fluorescence spectrometry 显示文摘 | MIRAVET R L PEZ - S NCHEZ J F RUB I R | 2004 | Analytica Chimica Acta2004，511，2： | 1 |
| 19 | Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes显示文摘 | Bertram M J Bérubé N G Hang-Swanson X | 1999 | Mol Cell Biol1999，19，2： | 1 |
| 20 | Re- quirement for glycogen synthase kinase -313 in cell sur- vival and NF - κ B activaton 显示文摘 | HOEFL I CH K P LUO J RUB IE E A | 2000 | Nature2000，406，6791： | 1 |
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