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| 1 | Effect of Ce doping into V_(2)O_(5)-WO_(3)/TiO_(2) catalysts on the selective catalytic reduction of NO_(x) by NH_(3)显示文摘In this work, the effectiveness of V_2O_5-WO_3/TiO_2 catalysts modified with different CeO_2 contents by impregnation and co-precipitation methods on the selective catalytic reduction of NOxby NH3 have been studied comparatively by various experimental techniques. The results showed that the NO conversion of V_2O_5-WO_3/CeO_2-TiO_2 catalysts modified by co-precipitation method obviously increased with the Ce doping contents in the studied range below 20%(All Ce contents are in mass fractions), but the NO conversion of V_2O_5-WO_3/CeO_2/TiO_2 catalysts modified by impregnation methods was lower than V_2O_5-WO_3/CeO_2-TiO_2 catalysts especially beyond 2.5% Ce doping contents. The V_2O_5-WO_3/CeO_2-TiO_2 catalysts showed better SCR activity, wider reaction window, and higher sulfur and water resistance. The characterization results elucidated that the modified catalysts by co-precipitation method exhibited higher specific surface area, much better dispersity of Ce component, more Ce^(3+)species and more Br?nsted acid sites than that by impregnation. The vacancies caused by more Ce^(3+)species were favorable for more NO oxidation to NO_2, and the interaction between Ce species and WOxspecies generated more Br?nsted acid sites. It could be supposed that dispersed Ce Oxspecies and WOxspecies offered more second active centers respectively to adsorb oxygen and activate ammonia as co-catalysis to the primary active center of V ions, thus facilitated the better SCR activity of modified V_2O_5-WO_3/CeO_2-TiO_2 catalysts by coprecipitation methods. The co-precipitation methods with Ce component were more suitable for production of modified commercial V_2O_5-WO_3/TiO_2 catalysts. | Mengyin Chen Mengmeng Zhao Fushun Tang Le Ruan Hongbin Yang Ning Li | 2017 | Journal of Rare Earths2017，35，12： | 18 |
| 2 | Western medication plus Traditional Chinese Medicine preparations in patients with chronic heart failure:a prospective,single-blind,randomized,controlled,and multicenter clinical trial显示文摘OBJECTIVE: To assess the efficacy and safety in patients with chronic heart failure(CHF) of Western medication plus Traditional Chinese Medicine(TCM) preparations.METHODS: This prospective, single-blind, randomized, controlled, and multicenter clinical trial began on September 17, 2008, and was completed on June 25, 2011. A total of 340 inpatients, aged 40-79 years, with exacerbating CHF from 10 hospitals were enrolled and randomly allocated within 24 h of admission. The trial included three intervention periods. During hospitalization, the control group received western medication for CHF and the treatment group received Danhong injection with Shenfu injection or Shenmai injection. After discharge,all patients were treated with Qiliqiangxin capsules and Buyiqiangxin tablets or a placebo for 6 months. After the 6-month intervention, both groups received only continuous western medication. The primary endpoint was all-cause mortality.The efficacy assessments were as follows: B-type natriuretic peptide(BNP), Lee's HF score, the 6-minute walking test(6 MWT), left ventricular ejection fraction(LVEF), and the Minnesota Living with Heart Failure Questionnaire(MLHFQ). The safety assessments were as follows: blood and urine routine examination, hepatic and renal function, electrolytes in blood and adverse events.RESULTS: Compared with the control group, the treatment group showed a 30.99% reduction in all-cause mortality and an improved survival rate.The treatment group showed greater improvement in 6 MWT(P = 0.02) than the control group on discharge, after 12-month follow-up, there was a time-group interaction for MLHFQ(P = 0.03). Incidence rate of adverse events and other relevant safety indexes were not statistically significant between the two groups.CONCLUSION: Western medication plus TCM treatment can increase 6-minute walking distance(improve exercise tolerance) and quality of life with heart failure patients. | Wang Xianliang Hou Yazhu Mao Jingyuan Zhao Yingqiang Niu Tianfu Yuan Ruyu Wang Yonggang Cui Jin-rong Shi Le Jia Xiuli Fan Ruihong Lin Qian Zhang Yan Li Zhijun Shang Hongcai Wang Baohe Wang Hongwu Wang Henghe Cui Xiaolei Soh Shanbin Ruan Jishou Zhang Boli | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 15 |
| 3 | Effect of Gd addition on mechanical and microstructural properties of Mg-xGd-2.6Nd-0.5Zn-0.5Zr cast alloys显示文摘The Mg-xGd-2.6Nd-0.5Zn-0.5Zr(x=0,3.0,4.5 and 6.0,wt.%)alloys were prepared by gravity casting and then T6 treatment.Microstructures of the alloy were observed using optical microscopy and scanning electron microscopy.Results show that the as-cast alloys contained network Mg3Gd phases,blocky and needle-like Mg12(Nd,Gd)phases.The a(Zr)particle inclusions in the a(Mg)matrix are also observed.Content of the secondary phases decreases as Gd content increases.Tensile test results show that the tensile and yield strengths of all the alloys increase as Gd content increases under the as-cast and T6 conditions,but the elongation exhibits the opposite trend.The blocky Mg12(Nd,Gd)phases appear and act as crack initiator and deteriorates the experimental alloys’ductility with the increase of Gd content,especially as Gd content increases to 6.0 wt.%,so the Mg-6.0Gd-2.6Nd-0.5Zn-0.5Zr alloy has the lowest elongation value compared to the other alloys studied.After T6 treatment,the Mg-4.5Gd-2.6Nd-0.5Zn-0.5Zr alloy exhibits the optimal mechanical properties both at room temperature and 250℃. | Liang Zhan Yi-zhi Le Zhi-jun Feng Yan-chun Lou Ming Ruan Hua-wen Li | 2020 | China Foundry2020，17，3： | 6 |
| 4 | Catalytic microwave assisted pyrolysis of aspen显示文摘The effect of catalysts on the microwave pyrolysis of aspen pellets was studied.A range of chlorides,nitrates and metal-oxides were added at 2%of the aspen mass(air dry aspen pellet weight basis).Chlorides in particular were found to favor liquid yield,especially the yield of water phase residue.Average liquid yield with added chlorides was 41%mass of the total biomass input,compared to 35%mass without catalyst.Metal-oxides were found to favor pyrolysis heavy oil,and thus total oil yield,since the yield of light oils seemed to be fairly constant.Nitrates were found to favor pyrolysis gas production.Pure light oils and light oils blended with diesel were found to be a potential diesel fuel substitute. | Johannes Moen Changyan Yang Bo Zhang Hanwu Lei Kevin Hennessy Yiqin Wan Zhiping Le Yuhuan Liu Paul Chen Roger Ruan | 2009 | International Journal of Agricultural and Biological Engineering2009，2，4： | 5 |
| 5 | Blue AIEgens bearing triphenylethylene peripheral:adjustable intramolecular conjugation and good device performance显示文摘The new approaches to construct deep blue aggregation-induced emission(AIE) materials have been explored, which control the conjugation by two different strategies, to make a great step for the commercialization of organic light-emitting diodes. In order to shorten the intramolecular conjugation length, triphenylethylene(t PE)was utilized to construct blue AIEgens as peripheral groups,instead of tetraphenylethylene(TPE), the famous AIE star molecule, to yield three blue AIEgens of 3,4-Bt PE-PI, 4,4-Bt PE-PI and 4,4-Bt PE-PPI. Nondoped electroluminescence devices are fabricated by using these three AIEgens as the emitting material layer, the best performance of 3.8 cd/A as the maximum current efficiency achieved at the commission internationale de l'Eclairage coordinates of(0.17, 0.18). | Can Wang Le Li Xuejun Zhan Zhijun Ruan Yujun Xie Quanyuan Hu Shanghui Ye Qianqian Li Zhen Li | 2016 | Science Bulletin2016，61，22： | 2 |
| 6 | The immunopharmacological properties of transforming growth factor-deta 显示文摘 | Le YY Yu X J Ruan LF | 2005 | Int Immunopharmacol2005，5，1314： | 1 |
| 7 | The immunopharmacological properties of transforming growth factor deta 显示文摘 | Le Y Yu X Ruan L | 2005 | Int Immunopharmacol2005，5，1314： | 1 |
| 8 | The immunopharma- cological properties of IL- 8 International Immuno- pharmacology显示文摘 | Le Y Yu X Ruan L | 2005 | 5(13 - 14) :1771 - 17822005，5，1314： | 1 |
| 9 | Dynamic 320-slice CT larynx for detection and management of idiopathic bilateral vocal cord paralysis显示文摘 | Ruane LE Lau KK Low K | 2014 | Respirol Case Rep2014，2，1： | 1 |
| 10 | The immunopharmacological properties of transform ing growth factor deta 显示文摘 | yingying Le xiaojing Yu lingfei Ruan et at | 2005 | International lmmunopharmacology2005，5，： | 1 |
| 11 | On the origin of SARS-CoV-2——The blind watchmaker argument显示文摘In the comparison with SARS-CoVof 2003,SARS-CoV-2 is extremely well adapted to the human populations and its adaptive shift from the animal host to humans must have been even more extensive.By the blind watchmaker argument,such an adaptive shift can only happen prior to the onset of the current pandemic and with the aid of step-by-step selection. | Chung-I Wu Haijun Wen Jian Lu Xiao-dong Su Alice CHughes Weiwei Zhai Chen Chen Hua Chen Mingkun Li Shuhui Song Zhaohui Qian Qihui Wang Bingjie Chen Zixiao Guo Yongsen Ruan Xuemei Lu Fuwen Wei Li Jin Le Kang Yongbiao Xue Guoping Zhao Ya-Ping Zhang | 2021 | Science China(Life Sciences)2021，64，9： | 1 |
| 12 | ZNF3 regulates proliferation,migration and invasion through MMP1 and TWIST in colorectal cancer显示文摘Colorectal cancer(CRC)is a malignant tumor with a high incidence and mortality worldwide.Currently,the underlying molecular mechanisms of CRC are still unclear.Zinc finger protein 3(ZNF3)is a zinc-finger transcription factor that has been reported as a candidate for breast cancer prognosis,suggesting its involvement in the regulation of tumorigenesis.However,the association between ZNF3 and CRC remains unknown.To investigate the role of ZNF3 in CRC,we first analyze the correlation between ZNF3 expression and CRC,and the results demonstrate that ZNF3 is highly expressed in CRC tissue and cells,which is associated with the age of CRC patients.In vitro studies show that ZNF3 overexpression promotes CRC cell migration.Compared to control cells,knockdown of ZNF3 markedly suppresses CRC cell proliferation,migration and invasion and promotes G0/G1 phase cell cycle arrest.The expressions of the EMT-related markers TWIST and MMP1 are significantly decreased when ZNF3 is silenced.Additionally,overexpression of MMP1 and TWIST exacerbates CRC cell proliferation,accelerates the S phase cell cycle in ZNF3-knockdown SW480 cells,and increases cell migration and invasion through Transwell chambers.These data suggest that ZNF3 is involved in cellular proliferation,migration and invasion by regulating MMP1 and TWIST in CRC cells. | Le Du Ning Liu Jianfeng Jin Meng Cao Yuantian Sun Xinzheng Gao Banzhan Ruan Shangfeng Yang Dongsheng Ge Yingzhuan Ye Yinxi Zhou Erfei Chen Jin Yang | 2022 | Acta Biochimica et Biophysica Sinica2022，54，12： | 1 |
| 13 | Targeting both sides of the GDF15-GFRALRET receptor complex:A new approach to achieve body weight homeostasis显示文摘Obesity is a chronic,complex disease,which is associated with several comorbidities,including diabetes mellitus,hypertension,and cardiovascular diseases.It is estimated that the prevalence of obesity among both adults and children nearly tripled between 1975 and 2016,highlighting a huge unmet treatment need.However,the currently available antiobesity drugs have serious side effects,which limit their long-term use.The finding that the newly-identified brain GDF15-GFRAL-RET receptor signaling complex is involved in stress/disease-induced anorexia will certainly impact our knowledge of body weight homeostasis under healthy and disease conditions.Based on this breakthrough,a new class of GFRAL/RETbased drugs is highly anticipated for the treatment of obesity,as well as cancer-induced cachexia. | Fei Li Xiongzhong Ruan Le Min | 2017 | Genes & Diseases2017，4，4： | 1 |
| 14 | The immunopharmacological properties of transforming growth factor delta 显示文摘 | Le YY Yu X J Ruan IF | 2005 | Int Immumopharmacol2005，5，1314： | 1 |
| 15 | Research progress on the relationship between proBDNF and alcohol dependence and its related cognitive impairment显示文摘Brain-derived neurotrophic factor(BDNF)plays an important role in the growth,develop-ment,differentiation,injury,repair,survival and apoptosis of nerve cells.Precursor of BDNF(proBDNF)is an im-portant regulator of neurodegeneration,long-term hippo-campal inhibition and synaptic plasticity.Alcohol depen-dence syndrome(ADS)is a group of chronic recurrent diseases with unknown etiology.Current studies believe that proBDNF plays an important role in the occurrence,development and outcome of ADS.Alcohol dependence patients,like other neurodegenerative diseases,will also have different degrees of cognitive impairment.This arti-cle reviews the research progress on the relationship be-tween BDNF,proBDNF,alcohol dependence and cogni-tive impairment. | Hongying Pan Lan Jiang Le Zhang Tiantian Jiang Tiankai Jiang Ye Ruan | 2022 | Journal of Translational Neuroscience2022，7，3： | 0 |
| 16 | Standardized Evaluation of Camera-based Driver State Monitoring Systems显示文摘Driver state sensing technologies, such as vehicular systems, start to be widely considered by automotive manufacturers. To reduce the cost and minimize the intrusiveness towards driving, the majority of these systems rely on the in-cabin camera(s) and other optical sensors. With their great capabilities in detecting and intervening of driver distraction and inattention,these technologies may become key components in future vehicle safety and control systems. However, to the best of our knowledge,currently, there is no common standard available to objectively compare the performance of these technologies. Thus, it is imperative to develop one standardized process for evaluation purposes.In this paper, we propose one systematic and standardized evaluation process after successfully addressing three difficulties:1) defining and selecting the important influential individual and environmental factors, 2) countering the effects of individual differences and randomness in driver behaviors, and 3) building a reliable in-vehicle driver head motion tracking tool to collect ground-truth motion data. We have collected data on a large scale on a commercial driver state-sensing platform. For each subject, 30 to 40 minutes of head motion data was collected and included variables, such as lighting conditions, head/face features,and camera locations. The collected data was analyzed based on a proposed performance measure. The results show that the developed process can efficiently evaluate an individual camerabased driver state sensing product, which builds a common base for comparing the performance of different systems. | Renran Tian Keyu Ruan Lingxi Li Jialiang Le Jeff Greenberg Saeed Barbat | 2019 | IEEE/CAA Journal of Automatica Sinica2019，6，3： | 0 |
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