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| 1 | Dectin- 1 isoforms contribute to distinct Th 1/Th 17 cell activation in mucosal candidiasis显示文摘β 的识别;由 dectin-1 的 -glucans 被显示了调停房间激活, cytokine 生产和许多抗真菌的回答。这里,我们报导在到 Candida albicans 的 mucosal 免疫的 dectin-1 的功能的活动被主人的基因背景影响。Dectin-1 在 C57BL/6,然而并非 BALB/c 老鼠为胃肠、阴道的 candidiasis 的合适的控制被要求;事实上,后者当 dectin-1 不在时显示出增加的抵抗。到感染的 dectin-1-deficient C57BL/6 老鼠的危险性在 IL-17A 和芳基烃受体依赖者 IL-22 生产并且在适应 Th1 回答与缺点被联系。相反, dectin-1-deficient BALB/c 鼠标的抵抗与增加的 IL-17A 和 IL-22 生产并且向提供免疫学的存储器的 Th1/Treg 有免疫力的回答扭曲被联系。迥异的正规 / 不在经典中的 NF-κ dectin-1 下游地表明小径的 B 在二不同老鼠紧张被激活。因此,在抗真菌的 mucosal 免疫的 dectin-1 的网活动依赖于主人的基因背景,它在 dectin-1 发信号之上影响天生的 cytokine 生产和适应 Th1/Th17 房间激活。 | Agostinho Carvalho Gloria Giovannini AntoneUa De Luca Carmen D'Angelo Andrea Casagrande Rossana G Iannitti Giovanni Ricci Cristina Cunha Luigina Romani | 2012 | Cellular & Molecular Immunology2012，9，3： | 10 |
| 2 | Sudden hearing loss associated with peginterferon and ribavirin combination therapy during hepatitis C treatment显示文摘在丙肝处理期间与木钉干扰素和 ribavirin 联系的不利效果是众所周知的。突然的听觉损失很少被报导了。包含的可能的机制包括干扰素,汽车免疫,和 hematological 变化的直接 ototoxicity。听觉损失充分经常在抗病毒的治疗的中止以后被解决。我们与长期的丙肝报导一个 47 岁的人,遗传型 2 交流在以木钉干扰素高山开始治疗以后开发了突然的听觉损失 22 wk 哈在 180 mug/wk 和 ribavirin 的剂量的 2a 800 mg 每天。因为症状没变得更坏,抗病毒的治疗为 2 wk 被继续,根据病人的愿望。听见损失在治疗的结束以后在 2 wk 以内解决了。浆液肝丙氨酸 aminotransferase 仍然保持正常在期间并且在抗病毒的治疗的结束以后。HCV RNA 在治疗的结束是无法发现的并且仍然保持否定 24 wk 以后。因此,病人们应该知道听觉损失可以与木钉干扰素治疗,而是决定发生是否继续或到站,治疗基于医生的临床的判断和病人的愿望。 | Héla Elloumi Fatma Houissa Najet Bel Hadj Dalila Gargouri Malika Romani Jamel Kharrat AbdelJabbar Ghorbel | 2007 | World Journal of Gastroenterology2007，13，40： | 4 |
| 3 | Zircon U-Pb Ages and Hf Isotopes of Neoproterozoic Meta-Igneous Rocks in the Liansandao Area,Northern Sulu Orogen,Eastern China,and the Tectonic Implications显示文摘The Sulu Orogen preserves the Neoproterozoic tectonic-magmatic events,corresponding to the breaking up of the Rodinia supercontinent.The ages and petrogenesis of meta-igneous rocks in the Liansandao area in the northern Sulu Orogen are not well-constrained.This study reports zircon U-Pb ages and Hf isotopes of these rocks from the Liansandao area.Three meta-igneous rock samples give similar weighted mean 206 Pb/238 U ages of 744±11,767±12,and 762±15 Ma,respectively,indicating the Neoproterozoic crystallization ages.These rocks formed coevally with the Wulian and Yangkou intrusions that located along the Yantai-Qingdao-Wulian fault zone.The Neoproterozoic ages indicate that the meta-igneous rocks from the Liansandao area have affinity to the Yangtze Block.The three samples haveεHf(t)values of-7.2–-10.5,-6.0–-17.5,and-6.8–-12.0,respectively.These negativeεHf(t)values indicate a primarily crustal source.However,the widely variousεHf(t)values that are higher than the continental crust,suggesting magma mixing between mantle-derived materials and the continental crust or source heterogeneity.Combined with the Hf model ages and geochemical characteristics,the monzodiorite(sample LSD-2)is most likely to be mantle-derived magma then interacted with ancient continental crust,and the granitic protolith(samples LSD-1 and LSD-3)in the Liansandao area might derive from the re-melting of a Paleoproterozoic continental crust at^750 Ma,resulting from the upwelling and underplating of mantle-derived magma formed in an extensional setting due to the break-up of the Rodinia supercontinent. | Zhaojun Song Huimin Liu Fanxue Meng Xingyu Yuan Qiao Feng Dingwu Zhou Juan Ramon Vidal Romani Hongbo Yan | 2019 | Journal of Earth Science2019，30，6： | 4 |
| 4 | Mapping and ultrastructure of antennal chemosensilla of the wheat bug Eurygaster maura显示文摘小麦的天线坏透臭虫 Eurygaster maura L。(半翅类:Scutelleridae ) 被调查阐明在女性的 antennal chemosensilla 的结构和分发。sensilla 的五种类型被识别并且描绘了使用一台扫描电子显微镜(SEM ) 和一台传播电子显微镜(TEM ) 。类型 1 sensilla 是机械的并且与一个单个顶端的毛孔联系化学受体。类型 2 和 3 sensilla 与嗅觉的 sensilla 的典型特征两个都是多多孔的化学受体。类型 4 是多多孔的像木钉的 sensilla,突然并且与投出的表面。类型 5 是 sensilla coeloconica 与一光滑并且完全在一个亚 cuticular 房间插入的一个多孔的木钉。所有类型在二个 flagellar 片断上被散布,但是我们考虑了仅仅 sensilla 的最大的数字位于的顶端的 flagellomere。最丰富的 sensilla 是类型 3,当时更少众多是类型 5。除了类型 2,所有类型从尖端在数字减少了到片断的底。sensilla 的更低的密度在顶端的 antennomere 的背面内部的部分上被记录,当更高的密度在相反的方面上被记录时(外部腹) 。 | Roberto Romani Marco Valerio Rossi Stacconi | 2009 | Insect Science2009，16，2： | 3 |
| 5 | Human epididymis protein 4 as a serum marker for diagnosis of endometrial carcinoma and prediction of clinical outcome显示文摘 | Laura Zanotti Eliana Bignotti Stefano Calza Elisabetta Bandiera Giuseppina Ruggeri Claudio Galli Germana Tognon Monica Ragnoli Chiara Romani Renata A. Tassi Luigi Caimi Franco E. Odicino Enrico Sartori Sergio Pecorelli Antonella Ravaggi | 2012 | Clinical Chemistry and Laboratory Medicine2012，，12： | 2 |
| 6 | Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte macrophage colonystimulating factor 显示文摘 | Inaba K Inaba M Romani N | 1992 | J Exp Med1992，176，： | 2 |
| 7 | Interleukin-16 Gene Polymorphisms Are Considerable Host Genetic Factors for Patients’ Susceptibility to Chronic Hepatitis B Infection显示文摘 | Sara Romani Seyed Masoud Hosseini Seyed Reza Mohebbi Shabnam Kazemian Shaghayegh Derakhshani Mahsa Khanyaghma Pedram Azimzadeh Afsaneh Sharifian Mohammad Reza Zali Piero Luigi Almasio | 2014 | Hepatitis Research and Treatment2014，，： | 2 |
| 8 | Automated Deep Learning Empowered Breast Cancer Diagnosis UsingBiomedical Mammogram Images显示文摘Biomedical image processing is a hot research topic which helps to majorly assist the disease diagnostic process.At the same time,breast cancer becomes the deadliest disease among women and can be detected by the use of different imaging techniques.Digital mammograms can be used for the earlier identification and diagnostic of breast cancer to minimize the death rate.But the proper identification of breast cancer has mainly relied on the mammography findings and results to increased false positives.For resolving the issues of false positives of breast cancer diagnosis,this paper presents an automated deep learning based breast cancer diagnosis(ADL-BCD)model using digital mammograms.The goal of the ADL-BCD technique is to properly detect the existence of breast lesions using digital mammograms.The proposed model involves Gaussian filter based pre-processing and Tsallis entropy based image segmentation.In addition,Deep Convolutional Neural Network based Residual Network(ResNet 34)is applied for feature extraction purposes.Specifically,a hyper parameter tuning process using chimp optimization algorithm(COA)is applied to tune the parameters involved in ResNet 34 model.The wavelet neural network(WNN)is used for the classification of digital mammograms for the detection of breast cancer.The ADL-BCD method is evaluated using a benchmark dataset and the results are analyzed under several performance measures.The simulation outcome indicated that the ADL-BCD model outperforms the state of art methods in terms of different measures. | JoséEscorcia-Gutierrez Romany F.Mansour Kelvin Belen Javier Jiménez-Cabas Meglys Pérez Natasha Madera Kevin Velasquez | 2022 | Computers, Materials & Continua2022，，6： | 2 |
| 9 | Immunity to fungal infections 显示文摘 | Romani L | 2004 | Nat Rev hn- munol2004，4，1： | 1 |
| 10 | Immunity to fungal infections 显示文摘 | Romani L | 2011 | Nat Rev Immu- nol2011，11，4： | 1 |
| 11 | Thymosin alphal: an endog- enous regulator of inflammation, immunity, and tolerance显示文摘 | Romani L Bistoni F Montagnoli C | 2007 | Ann N Y h6ad Sci2007，1112，： | 1 |
| 12 | Interleukin-16(IL-16)gene polymorphisms in Iranian patients with colorectalcancer显示文摘 | AzimzadehP Romani S Mohebbi SR | 2011 | J Gastrointestin Liver Dis2011，20，4： | 1 |
| 13 | Outlining a future lor non-Saccharomyces yeasts: Selection of putative spoilage wine strains to be used in association with Saccharomyces cerevisiae for grape juice fermentation显示文摘 | Domizio P Romani C Lencioni L | 2011 | International Journal of Food Microbiology2011，147，： | 1 |
| 14 | Piez- oelectric transducers for real-time evaluation of fruit firm- ness 显示文摘 | Enrico macrell Aldo Romani Rudi P Paganelli | 2013 | Sensor and Actuators A: Physical2013，201，： | 1 |
| 15 | Pseudomonas aeruginosa in patients hospitalised for COPD exacerbation: a prospective study 显示文摘 | Garcia Vidal C Almagro P Romani V | 2009 | Eur Respir J2009，34，5： | 1 |
| 16 | T cell subsets and INF-gamma production in resistance to systemic candidosis in immunized mice显示文摘 | Cenci E Romani L Vecchiarelli A | 1990 | J Immunol1990，144，11： | 1 |
| 17 | Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor显示文摘 | Inaba K Inaba M Romani N | 1992 | J Exp Med1992，176，6： | 1 |
| 18 | MRI and brainstem auditory evoked potential显示文摘 | Bergamaschi R Romani A | 1997 | Neurology1997，48，2： | 1 |
| 19 | Multiphase CFD simulation of a solid bowl centrifuge 显示文摘 | Romani Fernandez X Nirsehl H | 2009 | Chemical Engineering & Technology2009，32，5： | 1 |
| 20 | CD7 in acute myeloid leukemia:correlation with loss of wild-type CEBPA,consequence of epigenetic regulation显示文摘 | Rohrs S Scherr M Romani J | | 0，，： | 1 |
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