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| 1 | Contrast-enhanced ultrasound in diagnosis and characterization of focal hepatic lesions显示文摘The extensive use of imaging techniques in differential diagnosis of abdominal conditions and screening of hepatocellular carcinoma in patients with chronic hepatic diseases,has led to an important increase in identification of focal liver lesions.The development of contrastenhanced ultrasound(CEUS) opens a new window in the diagnosis and follow-up of these lesions.This technique offers obvious advantages over the computed tomography and magnetic resonance,without a decrease in its sensitivity and specificity.The new second generation contrast agents,due to their intravascular distribution,allow a continuous evaluation of the enhancement pattern,which is crucial in characterization of liver lesions.The dual blood supply in the liver shows three different phases,namely arterial,portal and late phases.The enhancement during portal and late phases can give important information about the lesion's behavior.Each liver lesion has a different enhancement pattern that makes possible an accurate approach to their diagnosis.The role of emerging techniques as a contrastenhanced three-dimensional US is also discussed.In this article,the advantages,indications and technique employed during CEUS and the different enhancement patterns of most benign and malignant focal liver lesions are discussed. | Inés Gómez Molins Juan Manuel Fernández Font Juan Carrero álvaro Jose Luís Lledó Navarro Marta Fernández Gil Conrado M Fernández Rodríguez | 2010 | World Journal of Radiology2010，2，12： | 14 |
| 2 | Impact of PRRSV on activation and viability of antigen presenting cells显示文摘Porcine reproductive and respiratory syndrome(PRRS) is one of the most important diseases of swine industry. The causal agent, PRRS-virus(PRRSV), is able to evade the host immune response and survive in the organism causing transient infections. Despite all scientific efforts, there are still some gaps in the knowledge of the pathogenesis of this disease. Antigen presenting cells(APCs), as initiators of the immune response, are located in the first line of defense against microorganisms, and are responsible for antigen recognition, processing and presentation. Dendritic cells(DCs) are the main type of APC involved in antigen presentation and they are susceptible to PRRSV infection. Thus, PRRSV replication in DCs may trigger off different mechanisms to impair the onset of a host effective immune response against the virus. On the one side, PRRSV may impair the basic functions of DCs by regulating the expression of major histocompatibility complex class Ⅱ and CD80/86. Other strategy followed by the virus is the induction of cell death of APCs by apoptosis, necrosis or both of them. The impairment and/or cell death ofAPCs could lead to a failure in the onset of an efficient immune response, as long as cells could not properly activate T cells. Future aspects to take into account are also discussed in this review. | Irene M Rodríguez-Gómez Jaime Gómez-Laguna Librado Carrasco | 2013 | World Journal of Virology2013，2，4： | 4 |
| 3 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 4 | Temperature-and salinity-decoupled overproduction of hydroxyectoine by Chromohalobacter salexigens 显示文摘 | Rodríguez M J Argando?a M Iglesias G F | 2013 | Applied and Environmental Microbiology2013，79，3： | 1 |
| 5 | Plant NHX cation/proton antiporters显示文摘 | Rodríguez-Rosales M P Gálvez F J Huertas R | 2009 | Plant Signaling&Behavior2009，4，4： | 1 |
| 6 | Wave height distribution in mixed sea-states显示文摘 | RODR(I)GUEZ G-R SOARES C G PACHECO M | | 0，，： | 1 |
| 7 | Active protection coatings with layered double hydroxide nanocontainers of corrosion inhibitor 显示文摘 | ZHELUDKEVICH M L POZNYAK S K RODR/GUES L M RAPS D HACK T DICK L F NUNES T FERREIRA M G S | 2010 | Corrosion Science2010，52，2： | 1 |
| 8 | Model predictive control of pH in tubular photobioreactors显示文摘 | Berenguel M Rodríguez F Acién F G | 2004 | Journal of Process Control2004，14，4： | 1 |
| 9 | Radiological and Pathological Assessment of Hepatocellular Carcinoma Response to Radiofrequency. A Study on Removed Liver after Transplantation显示文摘 | Juan C. Rodríguez-Sanjuán Francisco González Carlos Juanco Luis A. Herrera Mercedes López-Bautista Mónica González-Noriega Elena García-Somacarrera Javier Figols Manuel Gómez-Fleitas Martín Silván | 2008 | World Journal of Surgery2008，，7： | 1 |
| 10 | Wave period distribution in mixed sea-states显示文摘 | RODR(I)GUEZ G R SOARES C G PACHECO M | | 0，，： | 1 |
| 11 | Chronic melatonin treatment reduces the age-dependent inflammatory process in senescence-accelerated mice显示文摘 | Rodríguez M I Escames G López L C | 2007 | J Pineal Res2007，42，3： | 1 |
| 12 | Ebola outbreak killed 5000 gorillas显示文摘 | Bermejo M Rodríguez-Teijeiro J D Illera G | 2006 | Science2006，314，5805： | 1 |
| 13 | Three-level NPC converter-based predictive direct power control of the doubly fed induction machine at low constant switching frequency显示文摘 | Abad G Rodrí guez M Á Poza J | 2008 | IEEE Transactions on Industrial Electronics2008，55，12： | 1 |
| 14 | The combination of fructooligosaccharides and resistant starch shows prebiotic additive effects in rats显示文摘 | Maria Elena Rodríguez-Cabezas Desirée Camuesco Belén Arribas Natividad Garrido-Mesa Mònica Comalada Elvira Bailón Margarita Cueto-Sola Pilar Utrilla Eduardo Guerra-Hernández Carlos Pérez-Roca Julio Gálvez Antonio Zarzuelo | 2010 | Clinical Nutrition2010，，6： | 1 |
| 15 | Expression of seed dormancy in grain sorghum lines with contrasting preharvest sprouting behavior involves differential regulation of gibberellin metabolism genes显示文摘 | Rodríguez M V Mendiondo G M Cantoro R | | 0，，01： | 1 |
| 16 | Embolisation with Guglielmi detachable coils during the period of increased risk for cerebral vasospasm:early outcome显示文摘 | Lindgren H Rodríguez M | 2000 | Neuroradiology2000，42，： | 1 |
| 17 | Development,validation and application of micellar electrokinetic capillary chromatography method for routine analysis of catechins,quercetin and thymol in natural samples显示文摘 | L(O)PEZ M D C VILARI(N)O J M L RODR(I)GUEZ M V G | 2011 | Microchemical Journal2011，99，2： | 1 |
| 18 | Recent developments in quantification methods for metallothionein显示文摘 | Dabrio M Rodríguez A R Bordin G | 2002 | Journal of Inorganic Biochemistry2002，88，2： | 1 |
| 19 | Direct regulation of phytoene synthase gene expression and carotenoid biosynthesis by phytochrome-interacting factors显示文摘 | Toledo-Ortiz G Huq E Rodríguez-Concepción M | | 0，，： | 1 |
| 20 | Behavior of pharmaceuticals, cosmetics and hormones in a sewage treatment plant显示文摘 | Marta Carballa Francisco Omil Juan M Lema Mar??a Llompart Carmen Garc??a-Jares Isaac Rodr??guez Mariano Gómez Thomas Ternes | 2004 | Water Research2004，，12： | 1 |
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