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| 1 | Genome of Wild Mandarin and Domestication History of Mandarin显示文摘官员(柠檬 reticulata ) 是世界范围的最重要的柠檬庄稼之一。它的驯服被相信发生在华南,它是四几千年的官员耕作的中心之一。我们在 Nanling 区域附近收集了官员的自然野人口并且在附近栽培了 landraces。我们发现柠檬性的酸水平戏剧性地在栽培官员被减少。理解 ? 官员驯服的基因基础,我们 de novo 装配了野官员的一个草稿染色体并且分析了一套 104 个柠檬染色体。我们发现 Mangshan 官员是一种原始类型并且二个独立驯服事件发生了,分别地导致在北方和南方 Nanling 山的二组栽培官员(MD1 和 MD2 ) 。二个瓶颈和有效人口尺寸的二扩大为栽培官员的 MD1 组被识别。然而,在 MD2 组织 ? 在人口尺寸有长、连续的减少。MD1 和 MD2 官员从栽培 pummelo 种类显示出种间的基因渗入的不同模式。我们在官员的驯服期间在选择下面可能在基因在柠檬酸盐内容的规定包含了的 aconitate hydratase (ACO ) 识别了高分叉的一个区域,它是。这研究为现存野官员人口的地理起源提供具体基因证据并且使驯服和官员的进化历史清楚些。 | Lun Wang Fa He Yue Huang Jiaxian He Shuizhi Yang Jiwu Zeng Chongling Deng Xiaolin Jiang Yiwen Fang Shaohua Wen Rangwei Xu Huiwen Yu Xiaoming Yang Guangyan Zhong Chuanwu Chen Xiang Yan Changfu Zhou Hongyan Zhang Zongzhou Xie Robert M. Larkin Xiuxin Deng Qiang Xu | 2018 | Molecular Plant2018，11，8： | 14 |
| 2 | 超声辅助钼靶检测技术应用于不同乳腺癌风险女性的筛查效果评估显示文摘乳腺密度是影响乳腺癌发生与否的一个重要危险因素,对乳腺致密型妇女仅采用钼靶筛查的难度较大,因此有学者建议将全乳超声检查作为钼靶筛查的辅助手段,以改善乳腺致密型女性的疾病预后,但超声辅助钼靶检查是否可改善乳腺癌的筛查效率目前尚不明确。本研究基于2000年1月至2013年12月的美国两个乳腺癌监测联盟登记的前瞻性观察数据,对仅采用钼靶筛查和采用钼靶+超声筛查的两类人群进行了对比分析;共纳入3386名女性的6081次钼靶+超声筛查结果,并通过1∶5倾向性系数评分匹配了15176名女性的30062次钼靶筛查结果;排除标准为已知患乳腺癌或自述具有乳腺症状的女性;评价指标包括:癌症检出率、间期癌发生率、活检假阳性率、短间隔随访率,以及推荐活检阳性预测值等。 | 李婷媛 乔良(编译) Janie ML Robert FA Brian LS | 2019 | 中华预防医学杂志2019，53，11： | 6 |
| 3 | Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Statement for Health Professionals From the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association显示文摘 | Jane W. Newburger Masato Takahashi Michael A. Gerber Michael H. Gewitz Lloyd Y. Tani Jane C. Burns Stanford T. Shulman Ann F. Bolger Patricia Ferrieri Robert S. Baltimore Walter R. Wilson Larry M. Baddour Matthew E. Levison Thomas J. Pallasch Donald A. Fa | 2004 | Circulation2004，，17： | 2 |
| 4 | Randomized placebo-controlled study of recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in patients with breast cancer receiving dose-intensive cyclophosphamide and doxorubicin显示文摘 | Isaaes C Robert NJ Bailey FA | 1997 | J Clin Oncol1997，15，11： | 1 |
| 5 | Randomized placebo-controlled study of recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in patients with breast cancer receiving dose-intensive cyclophosphamide and doxorubicin显示文摘 | Isaacs C Robert NJ Bailey FA | 1997 | J Clin Oncol1997，15，： | 1 |
| 6 | Randomized placebo- controlled study of recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in patients with breast receiving dose-intensive cyclophosphamide and doxorubicin 显示文摘 | Isaacs C Robert N J Bailey FA | 1997 | J Clin Oncol1997，15，11： | 1 |
| 7 | Liver failurc with marked hyper ferritinenia:‘ironing out' the diagnosis显示文摘 | Natsheh SE Robert FA Ngan B | 2001 | Can J Gastroenterol2001，15，： | 1 |
| 8 | Randomized placebocontrolled study of recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in patients with breast cancer reveiving dose-intensive cyclophosphamide and doxorubicin显示文摘 | Isaacs C Robert NJ Bailey FA | 1997 | J Clin Oncol1997，15，11： | 1 |
| 9 | Randomized placebocontrolled study of recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in patients with breast cancer receiving dose-intensive cyelophosphamide and doxorubicin显示文摘 | Isaacs C Robert NJ Bailey FA | 1997 | J Clin Oncol1997，15，： | 1 |
| 10 | Randomized Placebo-controlled study of recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in patients with breast cancer receiving dose-intensive cyclophosphamide and doxorubicin显示文摘 | Isaccs C Robert N J Bailey FA | | 0，，11： | 1 |
| 11 | Randomized placebo- controlled study of recombinant humaninterleukin-ll to prevent chemotherapy-induced thrombocytopenia in patients with breast cancer receiving dose-intensive cyclophosphamide and doxorubicin 显示文摘 | Isaacs C Robert NJ Bailey FA | 1997 | Journal of clinical oncology:official journal of the American Society of Clinical Oncology1997，15，11： | 1 |
| 12 | Effect of high speed periodontal instruments on tooth surface显示文摘 | Edward FA Robert HR | 1963 | J Periodontol1963，34，： | 1 |
| 13 | Power distribu- tion across the face of different light guides and its effect on com- posite surface microhardness 显示文摘 | Vandewalle KS Roberts HW Rueggeberg FA | 2008 | J Esther Restor Dent2008，20，2： | 1 |
| 14 | Randomized placebo-controlled study of recombinant human interleukin-11 to prevent chemotherapy induced thrombocytopenia in patients with breast cancer receiving doseintensive cyclophosphamide and doxorubicin显示文摘 | Isaacs C Robert NJ Bailey FA | 1997 | J Clin Oncol1997，15，11： | 1 |
| 15 | Effects of porphy- romonas gingival and Escherichia coli lipopolysaccharides on mononuclear phagocyte 显示文摘 | Roberts FA Richardson GJ Michalek SM | 1997 | Infect Immun1997，65，8： | 1 |
| 16 | Randomized placebo - controlled study of recombinant human interleukin - 11 to pre- vent chemotherapy- induced thrombocytopenia in patients with breast cancer receiving dose - intensive cyclophosphamide and doxorubicin显示文摘 | Isaacs C Robert N J Bailey FA | 1997 | J Clin Ontol1997，15，11： | 1 |
| 17 | Randomized placebo controlled study of recombinant human interleukin 11 to prevent chemotherapy induced thrombocytopenia in patents with breast cancer receiving dose intensive cyclophosphamide and doxorubicin显示文摘 | Robert NJ Bailey FA | 1997 | J Clin Oncol1997，15，11： | 1 |
| 18 | Randomized placebo-controlled study of recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in patients with breast cancer receiving dose-intensive cyclophosphamide and doxorubicin 显示文摘 | Robert NJ Bailey FA | 1997 | J Clin Oncol1997，15，： | 1 |
| 19 | The Wilson disease gene : spectrum of mutations and their consequences显示文摘 | Thomas GR Forbes JR Roberts FA | 1995 | Nat Genet1995，9，： | 1 |
| 20 | Randomized placebo-controlled study of recombinant human interleukin-11 to prevent chemotherapy--induced thrombocytopenia in patients with breast cancer receiving dose-intensive cyclophosphamide and doxorubicin 显示文摘 | Isaacs C Robert N J Bailey FA | 1997 | Clin Oncol1997，15，11： | 1 |
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