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| 1 | AHA/ACC Guidelines for Secondary Prevention for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2006 Update: Endorsed by the National Heart, Lung, and Blood Institute显示文摘 | Sidney C. Smith Jerilyn Allen Steven N. Blair Robert O. Bonow Lawrence M. Brass Gregg C. Fonarow Scott M. Grundy Loren Hiratzka Daniel Jones Harlan M. Krumholz Lori Mosca Richard C. Pasternak Thomas Pearson Marc A. Pfeffer Kathryn A. Taubert | 2006 | Circulation2006，，19： | 4 |
| 2 | Randomized trial of mediastinal lymph node sampling versus complete lymphadenectomy during pulmonary resection in the patient with N0 or N1 (less than hilar) non–small cell carcinoma: Results of the American College of Surgery Oncology Group Z0030 Trial显示文摘 | Gail E. Darling Mark S. Allen Paul A. Decker Karla Ballman Richard A. Malthaner Richard I. Inculet David R. Jones Robert J. McKenna Rodney J. Landreneau Valerie W. Rusch Joe B. Putnam | 2011 | The Journal of Thoracic and Cardiovascular Surgery2011，，3： | 3 |
| 3 | MicroRNA-29 Regulates T-Box Transcription Factors and Interferon-γ Production in Helper T Cells显示文摘 | David F. Steiner Molly F. Thomas Joyce K. Hu Zhiyong Yang Joshua E. Babiarz Christopher D.C. Allen Mehrdad Matloubian Robert Blelloch K. Mark Ansel | 2011 | Immunity2011，，2： | 2 |
| 4 | Saving, dependency and development显示文摘 | Allen C. Kelley Robert M. Schmidt | 1996 | Journal of Population Economics1996，，4： | 2 |
| 5 | Strategies for PET imaging of the receptor for advanced glycation endproducts(RAGE)显示文摘The implication of the receptor for advanced glycation end-products(RAGE)in numerous diseases and neurodegenerative disorders makes it interesting both as a therapeutic target and as an inflammatory biomarker.In the context of investigating RAGE as a biomarker,there is interest in developing radiotracers that will enable quantification of RAGE using positron emission tomography(PET)imaging.We have synthesized potential small molecule radiotracers for both the intracellular([18F]InRAGER)and extracellular([18F]RAGER)domains of RAGE.Herein we report preclinical evaluation of both using in vitro(lead panel screens)and in vivo(rodent and nonhuman primate PET imaging)methods.Both radiotracers have high affinity for RAGE and show good brain uptake,but suffer from off-target binding.The source of the off-target PET signal is not attributable to binding to melatonin receptors,but remains unexplained.We have also investigated use of lipopolysaccharide(LPS)-treated mice as a possible animal model with upregulated RAGE for evaluation of new imaging agents.Immunoreactivity of the mouse brain sections revealed increases in RAGE in the male cohorts,but no difference in the female groups.However,it proves challenging to quantify the changes in RAGE due to off-target binding of the radiotracers.Nevertheless,they are appropriate lead scaffolds for future development of 2nd generation RAGE PET radiotracers because of their high affinity for the receptor and good CNS penetration. | Lindsey R.Drake Allen F.Brooks Jenelle Stauff Phillip S.Sherman Janna Arteaga Robert A.Koeppe Aimee Reed Timothy J.Montavon Marc B.Skaddan Peter J.H.Scott | 2020 | Journal of Pharmaceutical Analysis2020，10，5： | 2 |
| 6 | Video-assisted thoracic surgery versus open lobectomy for lung cancer: A secondary analysis of data from the American College of Surgeons Oncology Group Z0030 randomized clinical trial显示文摘 | Walter J. Scott Mark S. Allen Gail Darling Bryan Meyers Paul A. Decker Joe B. Putnam Robert W. Mckenna Rodney J. Landrenau David R. Jones Richard I. Inculet Richard A. Malthaner | 2010 | The Journal of Thoracic and Cardiovascular Surgery2010，，4： | 2 |
| 7 | More forks on the road to replication stress recovery显示文摘High-fidelity replication of DNA,and its accurate segregation to daughter cells,is critical for maintaining genome stability and suppressing cancer.DNA replication forks are stalled by many DNA lesions,activating checkpoint proteins that stabilize stalled forks.Stalled forks may eventually collapse,producing a broken DNA end.Fork restart is typically mediated by proteins initially identified by their roles in homologous recombination repair of DNA double-strand breaks(DSBs).In recent years,several proteins involved in DSB repair by non-homologous end joining(NHEJ)have been implicated in the replication stress response,including DNA-PKcs,Ku,DNA Ligase IV-XRCC4,Artemis,XLF and Metnase.It is currently unclear whether NHEJ proteins are involved in the replication stress response through indirect(signaling)roles,and/or direct roles involving DNA end joining.Additional complexity in the replication stress response centers around RPA,which undergoes significant post-translational modification after stress,and RAD52,a conserved HR protein whose role in DSB repair may have shifted to another protein in higher eukaryotes,such as BRCA2,but retained its role in fork restart.Most cancer therapeutic strategies create DNA replication stress.Thus,it is imperative to gain a better under-standing of replication stress response proteins and pathways to improve cancer therapy. | Chris Allen Amanda K.Ashley Robert Hromas Jac A.Nickoloff | 2011 | Journal of Molecular Cell Biology2011，3，1： | 2 |
| 8 | Polymorphism in the TNFα and TNF-receptor genes in patients with coronary artery disease显示文摘 | Allen RA Lee EM Roberts DH | 2001 | Eur J Clin Invest2001，31，： | 2 |
| 9 | Risky business:The role of risk in voluntary turnover decisions显示文摘 | David G Allen Robert W R Karen R MJarnes M V | 2007 | Human Resource Management Review2007，17，： | 1 |
| 10 | Expression and mapping of the mouse S7/Pmsc2 gene, homolog of an essential mitotic gene in yeast显示文摘 | Jeremy Allen Laurence Colleaux Duncan Davidson Elisabeth Graham Muriel Lee Robert Hill Cathy Abbott Colin Gordon | 1997 | Mammalian Genome1997，，5： | 1 |
| 11 | The Role of Coronary Artery Injury and Perfusion in the Development of Cardiac Contusion Secondary to Nonpenetrating Chest Trauma显示文摘 | ROBERT P. ALLEN A. JAMES LIEDTKE | 1979 | The Journal of Trauma: Injury Infection and Critical Care1979，，3： | 1 |
| 12 | Recombinant activated factor Ⅶ: its mechanism of action and role in the control of hemorrhage显示文摘 | Allen GA Hoffman M Roberts HR | 2002 | Can J Anaesth2002，49，： | 1 |
| 13 | Time to Rethink Long-Term Rehabilitation Management of Stroke Patients显示文摘 | Robert Teasell Swati Mehta Shelialah Pereira Amanda McIntyre Shannon Janzen Laura Allen Liane Lobo Ricardo Viana | 2012 | Topics in Stroke Rehabilitation2012，，： | 1 |
| 14 | Radiofrequency ablation of idiopathic left ventricular tachycardia at the site of earliest activation as determined by noncontact mapping显示文摘 | Roberts PR Allen SA | 2000 | J Cardiovasc Electrophysiol2000，11，10： | 1 |
| 15 | Performance of Delayed-Enhancement Magnetic Resonance Imaging With Gadoversetamide Contrast for the Detection and Assessment of Myocardial Infarction: An International, Multicenter, Double-Blinded, Randomized Trial显示文摘 | Raymond J. Kim Timothy S.E. Albert James H. Wible Michael D. Elliott John C. Allen Jennifer C. Lee Michele Parker Alicia Napoli Robert M. Judd | 2008 | Circulation2008，，5： | 1 |
| 16 | Perpetually Beginning until the End of the Fair: The Paratextual Poetics of Serialised Novels 显示文摘 | ALLEN ROBERT | 2010 | Nee- helicon2010，，37： | 1 |
| 17 | Caco-2 cell monolayers as a model for drug transport across the intestinal mucosa显示文摘 | ALLEN RH ROBERT AC PHILLIP SB | 1990 | PharmRes1990，7，9： | 1 |
| 18 | Semiparametric approaches to stochastic panel frontiers with applications in the banking industry显示文摘 | Robert M Adams Allen N Berger Robin C Sickles | 1999 | Journal of Business and Economic Statistics1999，17，3： | 1 |
| 19 | Thrombosing umbilical vein varix显示文摘 | Allen SL Bagnall C Roberts AB | | 0，，： | 1 |
| 20 | Effect of mutant IkappaB on cytokine-induced activation of NF-KappaB in cultured human RPE cells显示文摘 | Yang P McKay BS Allen JB Roberts WL Jaffe GJ | 2003 | Invest Ophthalmol Vis Sci2003，44，3： | 1 |
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