|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Too much interference: injection of double-stranded RNA has nonspecific effects in the zebrafish embryo显示文摘 | Oates A C Bruce A E and Ho RiK | 2000 | Dev Biol2000，224，： | 1 |
| 2 | Sandwich modeling with an applica-tion to the residual strength analysis of a damaged com-pression panel 显示文摘 | Riks E Rankin C | 2002 | International journal of Non-LinearMechanics2002，，： | 1 |
| 3 | Action of pinaverium bromide on calmodu- lin - regulated functions 显示文摘 | Frank W Greet DS Rik C | 1985 | Euro J Pharmacol1985，114，1： | 1 |
| 4 | Dexamethasone and length of hospital stay in patients with community-acquired pneumonia: a randomised, double-blind, placebo-controlled trial显示文摘 | Sabine CA Meijvis Hans Hardeman Hilde HF Remmelts Rik Heijligenberg Ger T Rijkers Heleen van Velzen-Blad G Paul Voorn Ewoudt MW van de Garde Henrik Endeman Jan C Grutters Willem Jan W Bos Douwe H Biesma | 2011 | The Lancet . 2011 (9782)2011，，： | 1 |
| 5 | On the solution of mode jumping phenomena in thin-walled shell structures 显示文摘 | Riks E Rankin C C Brogan F A | 1996 | Computer Methods in Applied Mechanics and Engineering1996，136，11： | 1 |
| 6 | Sandwich Modeling with an Application to the Residual Strength Analysis of a Damaged Compression Panel显示文摘 | Riks E Rankin C C | 2002 | International Journal of Non-Linear Mechanics2002，37，： | 1 |
| 7 | Longitudinal imaging of Alzheimer pathology using PIB, FDDNP and FDG PET显示文摘 | Rik O Nelleke T Jessica C | 2012 | Eur J Nucl Med Mol Imaging2012，39，： | 1 |
| 8 | Corrosion and mechanical properties of a novel biomedical WN43magnesium alloy prepared by spark plasma sintering显示文摘Alloying of Mg with rare-earth(RE)elements proved to be beneficial for their in-vitro and in-vivo performance.In this work,a novel WN43(Mg-4 wt%Y-3 wt%Nd)alloy with a well-defined composition was prepared,where,unlike in the commercial WE43 alloy,the possibly harmful RE mischmetal was substituted by less toxic Nd.A modern spark plasma sintering(SPS)technique was used to effectively produce WN43 samples from atomized powders.Sintering temperatures of 400℃-550℃ and holding times of 3 or 10 min were used and wellcompacted final materials were successfully prepared.It was shown that a superior combination of corrosion and mechanical properties was attained in the samples sintered at 500℃ and 550℃,while the effect of sintering time was rather negligible.The performance of this material was exceptional within the group of Mg alloys prepared by powder metallurgy and comparable with conventionally prepared alloys.Moreover,it was shown that a great variety of mechanical and corrosion characteristics can be obtained by altering the SPS parameters so as to fulfill case-specific requirements typical of biomedical materials.Consequently,the novel WN43 alloy prepared by SPS seems to be a particularly suitable material for biomedical use. | Michal Knapek Mária Zemková Adam Gres Eva Jablonská Frantisek Lukác Robert Král Jan Bohlen Peter Minárik | 2021 | Journal of Magnesium and Alloys2021，9，3： | 1 |
| 9 | Osteomodulin downregulation is associated with osteoarthritis development显示文摘Abnormal subchondral bone remodeling leading to sclerosis is a main feature of osteoarthritis(OA), and osteomodulin(OMD), a proteoglycan involved in extracellular matrix mineralization, is associated with the sclerotic phenotype. However, the functions of OMD remain poorly understood, specifically in vivo. We used Omd knockout and overexpressing male mice and mutant zebrafish to study its roles in bone and cartilage metabolism and in the development of OA. The expression of Omd is deeply correlated with bone and cartilage microarchitectures affecting the bone volume and the onset of subchondral bone sclerosis and spontaneous cartilage lesions. Mechanistically, OMD binds to RANKL and inhibits osteoclastogenesis, thus controlling the balance of bone remodeling. In conclusion, OMD is a key factor in subchondral bone sclerosis associated with OA. It participates in bone and cartilage homeostasis by acting on the regulation of osteoclastogenesis. Targeting OMD may be a promising new and personalized approach for OA. | Jérémie Zappia Qiao Tong Renée Van der Cruyssen Frederique MFCornelis Cécile Lambert Tiago Pinto Coelho Juliane Grisart Erika Kague Rik JLories Marc Muller Dirk Elewaut Chrissy LHammond Christelle Sanchez Yves Henrotin | 2023 | Bone Research2023，11，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员