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| 1 | Heat shock proteins: Molecules with assorted functions显示文摘Heat shock proteins (Hsps) or molecular chaperones, are highly conserved protein families present in allstudied organisms. Following cellular stress, the intracellular concentration of Hsps generally increases several folds.Hsps undergo ATP-driven conformational changes to stabilize unfolded proteins or unfold them for translocationacross membranes or mark them for degradation. They are broadly classified in several families according to theirmolecular weights and functional properties. Extensive studies during the past few decades suggest that Hsps play avital role in both normal cellular homeostasis and stress response. Hsps have been reported to interact with numeroussubstrates and are involved in many biological functions such as cellular communication, immune response, proteintransport, apoptosis, cell cycle regulation, gametogenesis and aging. The present review attempts to provide a briefoverview of various Hsps and summarizes their involvement in diverse biological activities. | Surajit SARKAR MDhruba SINGH Renu YADAV K.P.ARUNKUMAR Geoffrey W.PITTMAN | 2011 | Frontiers in Biology2011，6，4： | 3 |
| 2 | Lipid-polymer hybrid nanoparticles: Development & statistical optimization of norfloxacin for topical drug delivery system显示文摘Poly lactic acid is a biodegradable, biocompatible, and non-toxic polymer, widely used in many pharmaceuticalpreparations such as controlled release formulations, parenteral preparations, surgicaltreatment applications, and tissue engineering. In this study, we prepared lipid-polymer hybrid nanoparticlesfor topical and site targeting delivery of Norfloxacin by emulsification solvent evaporationmethod (ESE). The design of experiment (DOE) was done by using software to optimize the result, andthen a surface plot was generated to compare with the practical results. The surface morphology, particlesize, zeta potential and composition of the lipid-polymer hybrid nanoparticles were characterized bySEM, TEM, AFM, and FTIR. The thermal behavior of the lipid-polymer hybrid nanoparticles was characterizedby DSC and TGA. The prepared lipid-polymer hybrid nanoparticles of Norfloxacin exhibited anaverage particle size from 178.6 ± 3.7 nm to 220.8 ± 2.3 nm, and showed very narrow distribution withpolydispersity index ranging from 0.206 ± 0.36 to 0.383 ± 0.66. The surface charge on the lipid-polymerhybrid nanoparticles were confirmed by zeta potential, showed the value from t23.4 ± 1.5 mVto t41.5 ± 3.4 mV. An Antimicrobial study was done against Staphylococcus aureus and Pseudomonasaeruginosa, and the lipid-polymer hybrid nanoparticles showed potential activity against these two.Lipid-polymer hybrid nanoparticles of Norfloxacin showed the %cumulative drug release of 89.72% in24 h. A stability study of the optimized formulation showed the suitable condition for the storage oflipid-polymer hybrid nanoparticles was at 4 ± 2 C/60 ± 5% RH. These results illustrated high potential oflipid-polymer hybrid nanoparticles Norfloxacin for usage as a topical antibiotic drug carriers. | Vivek Dave Renu Bala Yadav Kriti Kushwaha Sachdev Yadav Swapnil Sharma Udita Agrawal | 2017 | Bioactive Materials2017，2，4： | 2 |
| 3 | Antimicrobialresistance profile of Salmonella present in poultry andpoultry environment in north India 显示文摘 | RENU S YADAV A S TRIPATHI V | 2013 | Food Control2013，33，2： | 1 |
| 4 | Curcumin suppresses the production of pro-inflammatory cytokine interleukin-18 in lipopolysaccharide stimulated murine macrophage-like cells显示文摘 | Renu Yadav Babban Jee Sudhir Kumar Awasthi | 2015 | Indian J Clin Biochem2015，30，1： | 1 |
| 5 | Homocystine Levels, Polymorphisms and the Risk of Ischemic Stroke in Young Asian Indians显示文摘 | Arijit Biswas Ravi Ranjan Arvind Meena Mohammad Suhail Akhter Birendra Kumar Yadav Murali Munisamy Vivekanandhan Subbiah Madhuri Behari Renu Saxena | 2009 | Journal of Stroke and Cerebrovascular Diseases2009，，2： | 1 |
| 6 | Homocystine Levels, Polymorphisms and the Risk of Ischemic Stroke in Young Asian Indians显示文摘 | Arijit Biswas Ravi Ranjan Arvind Meena Mohammad Suhail Akhter Birendra Kumar Yadav Murali Munisamy Vivekanandhan Subbiah Madhuri Behari Renu Saxena | 2009 | Journal of Stroke and Cerebrovascular Diseases2009，，2： | 1 |
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