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35篇 您的检索式:作者名="Reig S"
    题名 作者 年代 出处 被引量
1Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation显示文摘AIM:To evaluate the long-term results of conventional chemoradiotherapy and laparoscopic mesorectal excision in rectal adenocarcinoma patients without adjuvant therapy.METHODS:Patients with biopsy-proven adenocarcinoma of the rectum staged cT3-T4 by endoscopic ultrasound or magnetic resonance imaging received neoadjuvant continuous infusion of 5-fluorouracil for five weeks and concomitant radiotherapy.Laparoscopic surgery was planned after 5-8 wk.Patients diagnosed with ypT0N0 stage cancer were not treated with adjuvant therapy according to the protocol.Patients with ypT1-2N0 or ypT3-4 or N+were offered 5-fluorouracil-based adjuvant treatment on an individual basis.An external cohort was used as a reference for the findings.RESULTS:One hundred and seventy six patients were treated with induction chemoradiotherapy and 170underwent total mesorectal excision.Cancer staging of ypT0N0 was achieved in 26/170(15.3%)patients.After a median follow-up of 58.3 mo,patients withypT0N0 had five-year disease-free and overall survival rates of 96%(95%CI:77-99)and 100%,respectively.We provide evidence about the natural history of patients with localized rectal cancer achieving a complete response after preoperative chemoradiation.The inherent good prognosis of these patients will have implications for clinical trial design and care of patients.CONCLUSION:Withholding adjuvant chemotherapy after complete response following standard neoadjuvant chemoradiotherapy and laparoscopic mesorectal excision might be safe within an experienced multidisciplinary team.Xabier García-Albéniz Rosa Gallego Ralf Dieter Hofheinz Gloria Fernández-Esparrach Juan Ramón Ayuso-Colella Josep Antoni Bombí Carles Conill Miriam Cuatrecasas Salvadora Delgado Angels Ginés Rosa Miquel Mario Pagés Estela Pineda Verónica Pereira Aarón Sosa Oscar Reig Iván Victoria Luis Feliz Antonio María de Lacy Antoni Castells Iris Burkholder Andreas Hochhaus Joan Maurel 2014World Journal of Gastroenterology2014,20,42:5
2Progressive brain changes in children and adolescents with first-episode psychosis显示文摘Arango C Rapado-Castro M Reig S 2012Arch Gen Psychiatry2012,69,:1
3Increase in gray matter and decrease in white matter volumes in the cortex during treatment with atypical neuroleptics in schizophrenia显示文摘Molina V Reig S Sanz J 0,,:1
4Progressive brain changes in children and adolescents with first-episode psychosis显示文摘Arango C Rapado-Castro M Reig S 2012Arch Gen Psychiatry2012,69,1:1
5Trochanteric gamma nail and compression hip screw for trochanteric fractures:a randomized,prospective,comparative study in 210 elderly patients with a new design of the gamma nail显示文摘Utrilla A L Reig J S Munoz F M 2005J Orthop Trauma2005,19,4:1
6N-acetyl-aspartate levels in the dorsolateral prefrontal cortex in the early years of schizophrenia are inversely related to disease duration显示文摘Molina V Sánchez J Reig S 2005Schizophr Res2005,73,:1
7Cardiotoxicty of ropioacaine a new amide local anaesthetic agent 显示文摘Reig S Haggmark S Johansson G 1989Acta Anaesthesiol Scand1989,33,:1
8Study andDating of Medieval Ceramic Tiles by Analysis of Enamelswith Atomic Absorption Spectroscopy, X-ray Fluorescenceand Electron Probe Microanalysis 显示文摘Ramos S S Reig F B Adelantado J V G 2002SpectrochimicaActa Part B2002,57,:1
9Treatment of early hepatocellular carcinoma: towards personalized therapy 显示文摘Tremosini S Reig M de Lope CR 2010Dig Liver Dis2010,42,3:1
10Trochanteric gamma nail and compression hip screw for trochanteric fractures:a random-ized,prospective,comparative study in 210 elderly patients with a new design of the gamma nail显示文摘Utril a A L Reig J S Munoz F M 0,,04:1
11Hypofrontality in men with first-episode psychosis 显示文摘Molina V Sanz J Reig S 2005Br J Psychiatry2005,186,1:1
12Olanzapine-induced cere-bral metabolic changes related to symptom improvement in schizo-phrenia 显示文摘Molina V Gispert J D Reig S 2005Int Clin Psychopharmacol2005,20,1:1
13Complete angiographic obliteration of intracranial AVMs with endovascular embollzation :incomplete embolic nidal opacification is associated with AYYl recurrence 显示文摘Reig AS Rajaram R Simon S 2010J Neurointerv Surg2010,2,3:1
14Concentration of nacl from seawater reverse osmosis brines for the chlor-alkali industry by electrodialysis显示文摘Reig M Casas S Aladjem C el al 2014Desalination2014,342,:1
15Hypofrontality in men with first-episode psychosis显示文摘Molina V Sanz J Reig S 2005Br J Psychiatry2005,186,:1
16Long-term re- sults of the surgical treatment of type acromioclavicu lar dislocations:an update of a previous report显示文摘Lizaur A Sanz Reig J Gonzalez-Parreno S 2011J Bone Joint Surg Br2011,93,8:1
17Brain morphology and neurological soft signs in adolescents with first-episode psychosis显示文摘Janssen J Diaz-Caneja A Reig S 2009Br J Psychiatry2009,195,3:1
18Hypofmntality in men with first-episode psychosis显示文摘 J Sanz S Reig 2005British Journal of Psychiatry2005,186,:1
19Influence of tank geometry and flow pattern in fish distribution显示文摘DUARTE S REIG L MASAL谗I 0,,:1
20Validation of a method for the determination of boron in ceramic materials by X - ray fluorescence spectrometry 显示文摘Sanchez - Ramos S Bosch - Reig F Gimeno - Adelantado J V 2000Spectrochim Acta Part B2000,55,:1
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