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25篇 您的检索式：作者名="Regis O"

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	题名	作者	年代	出处	被引量
1	Notch signaling controls chondrocyte hypertrophy via indirect regulation of Sox9显示文摘RBPjk-dependent Notch signaling regulates both the onset of chondrocyte hypertrophy and the progression to terminal chondrocyte maturation during endochondral ossification. It has been suggested that Notch signaling can regulate Sox9 transcription, although how this occurs at the molecular level in chondrocytes and whether this transcriptional regulation mediates Notch control of chondrocyte hypertrophy and cartilage development is unknown or controversial. Here we have provided conclusive genetic evidence linking RBPjk-dependent Notch signaling to the regulation of Sox9 expression and chondrocyte hypertrophy by examining tissuespecific Rbpjk mutant(Prx1Cre;Rbpjkf/f), Rbpjk mutant/Sox9 haploinsufficient(Prx1Cre;Rbpjkf/f;Sox9f/1),and control embryos for alterations in SOX9 expression and chondrocyte hypertrophy during cartilage development. These studies demonstrate that Notch signaling regulates the onset of chondrocyte maturation in a SOX9-dependent manner, while Notch-mediated regulation of terminal chondrocyte maturation likely functions independently of SOX9. Furthermore, our in vitro molecular analyses of the Sox9 promoter and Notch-mediated regulation of Sox9 gene expression in chondrogenic cells identified the ability of Notch to induce Sox9 expression directly in the acute setting, but suppresses Sox9 transcription with prolonged Notch signaling that requires protein synthesis of secondary effectors.	Anat Kohn Timothy P Rutkowski Zhaoyang Liu Anthony J Mirando Michael J Zuscik Regis J O'Keefe Matthew J Hilton	2015	Bone Research2015，3，3：	8
2	Paraffin/porous-graphite matrix composite as a high and constant power thermal stor- age material显示文摘	Xavier Py Regis O Sylvain M	2001	Int J Heat Mass Transfer2001，44，：	1
3	Periprosthetic osteolysis: an immunologist?s update显示文摘	R John Looney Edward M Schwarz Allen Boyd Regis J O?Keefe	2006	Current Opinion in Rheumatology2006，，1：	1
4	Paraffin/porous graphite matrix composite as a high and constant power thermal storage material 显示文摘	Xavier P Regis O Sylvain M	2001	International Journal of Heat and Mass Transfer2001，44，14：	1
5	Paraffin/porous-graphite-matrix composite as a high and constant power thermal storage material显示文摘	Xavier P Regis O Sylvain M	2001	International Journal of Heat and Mass Transfer2001，44，：	1
6	Bienzyme car-bon paste electrodes for L-glutamate determination显示文摘	Ghobadi S Cs(o)regi E Marko-Varga G	1996	Curr Sep1996，14，：	1
7	Low Frequency Noise Properties of SiGe HBTs and Application to Ultral-Low PhaseNoise Osicillator显示文摘	Van Haaren V Regis M Llopis O	1998	IEEE Transaction Microwave Theory Techniques1998，46，5：	1
8	Radiosurgery for intractable epilepsy显示文摘	Regis J Levvier O Hayashi M	2003	Radiosurgery2003，9，3：	1
9	Runx2-mediated regulation of the zinc finger Osterix/Sp7 gene显示文摘	Yasuhiko Nishio Yufeng Dong Mark Paris Regis J. O'Keefe Edward M. Schwarz Hicham Drissi	2006	Gene2006，，：	1
10	显示文摘	Xavier Py Regis O Sylvain M	2001	International Journal of Heat and Mass Transfer2001，44，：	1
11	Mentoring Entrepreneurial Networks:mapping conceptions of participants in technological-based business incubators in Brszil显示文摘	Helder Pontes Regis James Anthony Falk S(o)nia Mafia R Calado Dias Antonio Virgilio Bittencourt Bastos	2007	REDES-Revista hispana para el aná1isis de redes sociales2007，，07：	1
12	Pineal region tumors:the role of stereotactic radiosurgery显示文摘	Regis J Chinot O	1996	Stereotact Funct Neurosurg1996，66，16：	1
13	Endogenous tissue engineering: PTH therapy for skeletal repair显示文摘	Masahiko Takahata Hani A. Awad Regis J. O’Keefe Susan V. Bukata Edward M. Schwarz	2012	Cell and Tissue Research2012，，3：	1
14	Paraffin/porous-graphite-matrix composite as a high and constant power thermal storage material 显示文摘	XAVIER P REGIS O SYLVA1N M	2001	Int J Heat2001，44，：	1
15	Comparison of aminolevulinic acid- and hexylester aminolevu-linate-induced protoporphyrin Ⅸ fluorescence for the detection of ovarian cancer in a rat model显示文摘	Regis C Collinet P Farine M O	2007	Photomed Laser Surg2007，25，：	1
16	Low-frequency noise properties of SiGe HBTs and application to ultra-low phase-noise oscillators 显示文摘	Van Haaren B Regis M Llopis O	1996	IEEE Trans Microwave Theory Tech1996，46，5：	1
17	Paraffin/porous-graphite-matrix composite as a high and constant power thermal storage material 显示文摘	Xavier P Regis O Sylvain M	2001	International Journal of Heat and Mass Transfer2001，44，14：	1
18	Paraffin/porous-graphite-matrix composite as a high and constant power thermal storage material 显示文摘	XAVIER P Y ReGIS O SYLVAIN M	2001	Inter J Heat Mass Transfer2001，44，：	1
19	Smurf2 induces degradation of GSK-3β and upregulates β-catenin in chondrocytes: A potential mechanism for Smurf2-induced degeneration of articular cartilage显示文摘	Qiuqian Wu Jason H. Huang Erik R. Sampson Kyung-OK Kim Michael J. Zuscik Regis J. O’Keefe Di Chen Randy N. Rosier	2009	Experimental Cell Research2009，，14：	1
20	An optimal control of a wastewater treatment reactor by catalytic ozonation显示文摘	Manhal A Regis O Driss M	2013	Control Engineering Practice2013，21，1：	1

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