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37篇 您的检索式:作者名="Reddy RN"
    题名 作者 年代 出处 被引量
1Sensory-motor responses to mechanical stimulation of the esophagus after sensitization with acid显示文摘AIM: Sensitization most likely plays an important role in chronic pain disorders, and such sensitization can be mimicked by experimental acid perfusion of the esophagus.The current study systematically investigated the sensory and motor responses of the esophagus to controlled mechanical stimuli before and after sensitization.METHODS: Thirty healthy subjects were included.Distension of the distal esophagus with a balloon was performed before and after perfusion with 0.1 mol/L hydrochloric acid for 30 min. An impedance planimetry system was used to measure cross-sectional area,volume, pressure, and tension during the distensions. A new model allowed evaluation of the phasic contractions by the tension during contractions as a function of the initial muscle length before the contraction (comparable to the Frank-Starling law for the heart). Length-tension diagrams were used to evaluate the muscle tone before and after relaxation of the smooth muscle with butylscopolamine.RESULTS: The sensitization resulted in allodynia and hyperalgesia to the distension volumes, and the degree of sensitization was related to the infused volume of acid. Furthermore, a nearly 50% increase in the evoked referred pain was seen after sensitization. The mechanical analysis demonstrated hyper-reactivity of the esophagus following acid perfusion, with an increased number and force of the phasic contractions, but the muscle tone did not change.CONCLUSION: Acid perfusion of the esophagus sensitizes the sensory pathways and facilitates secondary contractions.The new model can be used to study abnormal sensorymotor mechanisms in visceral organs.Asbjφrn Mohr Drewes Hariprasad Reddy Camilla Staahl Jan Pedersen Peter Funch-Jensen Lars Arendt-Nielsen Hans Gregersen 2005World Journal of Gastroenterology2005,11,28:3
2Increased cyclooxygenase- 2 levels in carcinopen -induced rat colomic tumors 显示文摘Dubois RN Radhika A Reddy BS 1996Gastroenterology1996,110,4:1
3Evidence that selective endothelial dysfunction may occur in the absence of angiographic or ultrsound atherosclerosis in patients with risk factors for atherosclerosis显示文摘 Nair RN Sheehan HM 1994J Am Coll Cardiol1994,23,:1
4Evidence that selective endothelial dysfunction may occur in the absence of angiographic or ultrasound atherosclerosis in patients with risk factory for atherosclerosis显示文摘Reddy KG Nair RN Sheehan HM 1994J Am Coll Cardiol1994,23,:1
5Increased cyclooxy2 Genase 22 levels in carcinogen2induced rat clonic tumors显示文摘DuBios RN Radhika A Reddy BS 2000Gastroenterolgy2000,110,6:1
6Gender Differences in Pain and Biomechanical Responses After Acid Sensitization of the Human Esophagus显示文摘Hariprasad Reddy MD Lars Arendt-Nielsen PhD Camilla Staahl MScPharm Jan Pedersen MD PhD Peter Funch-Jensen MD PhD Hans Gregersen MD PhD Asbj?rn Mohr Drewes MD PhD 2005Digestive Diseases and Sciences2005,,11:1
7Differences Between Male and Female Responses to Painful Thermal and Mechanical Stimulation of the Human Esophagus显示文摘Jan Pedersen Hariprasad Reddy Peter Funch-Jensen Lars Arendt-Nielsen Hans Gregersen Asbj?rn Mohr Drewes 2004Digestive Diseases and Sciences (-)2004,,7:1
8Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors显示文摘DuBios RN Radhika A Reddy BS 1996Gastroenterology1996,110,:1
9Evidence that selective endothelial dysfunction may occur in the absence of angiographic or ultrasound atherosclerosis in patients with risk factory for atherosclerosis显示文摘Reddy KG Nair RN Sheehan HM 1994J Am Coll Cardiol1994,23,:1
10Gender Differences in Pain and Biomechanical Responses After Acid Sensitization of the Human Esophagus显示文摘Hariprasad Reddy MD Lars Arendt-Nielsen PhD Camilla Staahl MScPharm Jan Pedersen MD PhD Peter Funch-Jensen MD PhD Hans Gregersen MD PhD Asbj?rn Mohr Drewes MD PhD 2005Digestive Diseases and Sciences2005,,11:1
11Evidece that selective Endo- thelial Dysfunction may occur in the absece of angiographic or Ultra- sound athemselerosis in Patiems with risk factors foratheroscl - erosis 显示文摘Reddy KG Nair RN Sheeharl HM 1994JAM Coll Cardiol1994,23,:1
12Electrostatic charge effect on respirable aerosol particle deposition in a cadaver based throat cast replica 显示文摘Ali M Reddy RN Mazumder MK 2008JElectrostat2008,66,78:1
13Evidence that elective endothelial dysfunction may occur in the absence of angiographic or ultrasound atherosclerosis in patients with risk factors for atherosclerosis显示文摘Reddy KG Nire RN Sheehan HM 1994J Am Coll Cardiol1994,23,4:1
14Evidence that selective endothelial dysfunction may occur in the absence of angiographic or ultrasound atherosclerosis in patients with risk factors for athero-sclerosis 显示文摘Reddy KG Nair RN sheehan HM 1994J Am Coll Cardiol1994,23,:1
15Increased cyclooxygenas e-2 levels in carcinogen-induced rat colonic tumors显示文摘DuBios RN Radhika A Reddy BS 1996Gastroenterolog y1996,110,:1
16Evidence that elective endothelia dysfunction may occur in the absence of angiographic or ultrasound atherosclerosis in patients with risk factor for atherosclerosis显示文摘Reddy KG Nire RN Sheehan HM 1994JACC1994,23,4:1
17Sol-gel MnO2 as an electrode material for electrochemical capacitors 显示文摘Reddy RN Reddy R G 2003Journal of Power Sources2003,124,:1
18Evidence that selective endothelial dysfunction may occur in ahsence of angiographie or ultrasound atherosclerosis in patients with factors for atherosclerosis显示文摘Reddy KG Nair RN Sheeham HM 1994J Am Coll Cardiol1994,23,:1
19Increased cyclooxygenase-2levels in carcinogen-induced rat colomic tumors显示文摘DuBois RN Radhika A Reddy BS 1996Gastroenterology1996,110,4:1
20Evidevce that selective endothelial dysfunction may occur in the absence of angiographic or ultrasound atherosclerosis in patients with risk factors for atherosclerosis显示文摘Reddy KG Nair RN Sheehan HM 1994J Am Coll Cardiol1994,23,9:1
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