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| 1 | Embolization of liver tumors:Past,present and future显示文摘Curative therapies for hepatocellular carcinoma(HCC),such as resection and liver transplantation,can only be applied in selected patients with early tumors.More advanced stages require local or systemic therapies.Resection of HCC offers the only hope for cure.Even in patients undergoing resection,recurrences are common.Chemoembolization,a technique combining intraarterial chemotherapy with selective tumor ischemia,has been shown by randomized controlled trials to be efficacious in the palliative setting.There is now renewed interest in transarterial embolization/transarterial chemoembolization(TACE) with regards to its use as a palliative tool in a combined modality approach,as a neoadjuvant therapy,in bridging therapy before transplantation,for symptomatic indications,and even as an alternative to resection.There have also been rapid advances in the agents being embolized trans-arterially(genes,biological response modifiers,etc.).The current review provides an evidence-based overview of the past,present and future trends of TACE in patients with HCC. | Ashwin Rammohan Jeswanth Sathyanesan Sukumar Ramaswami Anand Lakshmanan Perumal Senthil-Kumar Ulagendra Perumal Srinivasan Ravi Ramasamy Palaniappan Ravichandran | 2012 | World Journal of Radiology2012，4，9： | 11 |
| 2 | LC and LC–MS/MS studies for the identification and characterization of degradation products of acebutolol显示文摘The aim of the present investigation was to demonstrate an approach involving use of liquid chromatography(LC) and liquid chromatography-mass spectrometry(LC–MS) to separate, identify and characterize very small quantities of degradation products(DPs) of acebutolol without their isolation from the reaction mixtures. The drug was subjected to oxidative, hydrolytic, thermal and photolytic stress conditions as per International Conference on Harmonization(ICH) guideline Q1 A(R2). Among all the stress conditions the drug was found to be labile in hydrolytic(acidic & basic) and photolytic stress conditions, while it was stable in water-induced hydrolysis, oxidative and thermal stress conditions. A total of four degradation products were formed. A C18 column was employed for the separation of all the DPs on a gradient mode by using high-performance liquid chromatography(HPLC). All the DPs were characterized with the help of their fragmentation pattern and the masses obtained upon LC–MS/MS and MSnanalysis. All the hitherto unknown degradation products were identified as 1-(2-(2-hydroxy-3-(isopropylamino)propoxy)-5-(amino)phenyl)ethanone(DP-I), N-(4-(2-hydroxy-3-(isopropylamino)propoxy)-3-acetylphenyl)acrylamide(DP-II), 1-(2-(2-hydroxy-3-(isopropylamino)propoxy)-5-(hydroxymethylamino)phenyl)ethanone(DP-III) and 1-(6-(2-hydroxy-3-(isopropylamino)propoxy)-2,3-dihydro-2-propylbenzo[d]oxazol-5-yl)ethanone(DP-IV). Finally the in-silico carcinogenicity and hepatotoxicity predictions of the drug and all the DPs were performed by using toxicity prediction softwares viz., TOPKAT, LAZAR and Discovery Studio ADMET. The results of in-silico toxicity studies revealed that acebutolol(0.967) and DP-I(0.986) were found to be carcinogenic, while acebutolol(0.490) and DP-IV(0.437) were found to be hepatotoxic. | Uday Rakibe Ravi Tiwari Anand Mahajan Vipul Rane Pravin Wakte | 2018 | Journal of Pharmaceutical Analysis2018，8，6： | 2 |
| 3 | LC,MS^n and LC-MS/MS studies for the characterization of degradation products of amlodipine显示文摘In the present study,comprehensive stress testing of amlodipine(AM) was carried out according to International Conference on Harmonization(ICH) Q1A(R2) guideline.AM was subjected to acidic,neutral and alkaline hydrolysis,oxidation,photolysis and thermal stress conditions.The drug showed instability in acidic and alkaline conditions,while it remained stable to neutral,oxidative,light and thermal stress.A total of nine degradation products(DPs) were formed from AM.which could be separated by the developed gradient LC method on a C_(18) column.The products formed under various stress conditions were investigated by LC-MS/MS analysis.The previously developed LC method was suitably modified for LC-MS/MS studies by replacing phosphate buffer with ammonium acetate buffer of the same concentration(pH 5.0).A complete fragmentation pathway of the drug was first established to characterize all the degradation products using LC-MS/MS and multi-stage mass(MS^n) fragmentation studies.The obtained mass values were used to study elemental compositions,and the total information helped with the identification of DPs.along with its degradation pathway. | Ravi N.Tiwari Nishit Shah Vikas Bhalani Anand Mahajan | 2015 | Journal of Pharmaceutical Analysis2015，5，1： | 2 |
| 4 | ConChat: A Context-Aware Chat Program显示文摘 | Anand Ranganathan Roy H Campbell Arathi Ravi | 2002 | IEEE Pervasive Computing July-sept2002，1，3： | 1 |
| 5 | Group Buying on the Web: A Comparison of Price-Diseovery Mechanisms 显示文摘 | KrISHNAN S ANAND RAVI ARON | 2003 | Management Science2003，，49： | 1 |
| 6 | The International Suicide Prevention Trial (InterSePT): Rationale and Design of a Trial Comparing the Relative Ability of Clozapine and Olanzapine To Reduce Suicidal Behavior in Schizophrenia and Schizoaffective Patients显示文摘 | Larry Alphs Ravi Anand M. Zahur Islam Herbert Y. Meltzer John M. Kane Ranga Krishnan Alan I. Green Steven Potkin Guy Chouinard Jean-Pierre Lindenmayer Rob Kerwin | 2004 | Schizophrenia Bulletin2004，，： | 1 |
| 7 | Group Buying on the Web:A Comparison of Price-Discovery Mechanisms显示文摘 | Anand Krishnan S Aron Ravi | | 0，，11： | 1 |
| 8 | Percutaneous ultrasound-guided fine-needle aspiration of portal vein thrombi as a diagnostic and staging technique for hepatocellular carcinoma显示文摘 | Ashwin Rammohan S. Jeswanth R. Sukumar L. Anand P. Senthil Kumar U. P. Srinivasan R. Ravi P. Ravichandran | 2013 | Abdominal Imaging2013，，5： | 1 |
| 9 | Molybdenum disulfide-graphene van der Waals heterostructures as stable and sensitive electrochemical sensing platforms显示文摘Atomic layers are sought after for molecular sensing due to their available high surface interaction area,and different types of monolayers are attempted for sensing in the recent past.However,their chemical stability towards these molecules is questioned in recent times and alternate methods need to be developed to circumvent such issues,while maintaining high sensitivity.Here,the van der Waals(vdWs)stacks of molybdenum disulfide(MoS_(2))and graphene are shown for their stable electrochemical sensing towards ascorbic acid(AA)and dopamine(DA)-two important biomolecules.AA is known to chemically react with MoS_(2) leading to unstable sensing platform,while here the graphene coverage is shown to protect the MoS_(2) even from low-energy plasma exposure while keeping the same high sensitivity.Upon proving the graphene-based protection of the sensor,such a sensing platform is shown for its applicability in DA sensing,where it is found to give a linear response in a wide range of concentrations(2.5 to 600μmol·L^(−1))and even selective sensing in the presence of AA.Such a stack is found to be not merely giving protection to the beneath MoS_(2) layer but also the inter-layer charge transfer due to work function differences being beneficial in bringing fast and high sensitivity to the next-generation sensors and point-of-care devices. | Stelbin Peter Figerez Kiran Kumar Tadi Krishna Rani Sahoo Rahul Sharma Ravi K.Biroju Aleena Gigi KAiswarya Anand Golap Kalita Tharangattu N.Narayanan | 2020 | Tungsten2020，2，4： | 1 |
| 10 | 应用卡巴拉汀治疗轻到中重度阿尔茨海默病患者52周有效性研究(译文)显示文摘卡巴拉汀酒石酸盐 ( ENA71 3,艾斯能 )是具有中枢活性的胆碱酯酶抑制剂。通过为期 2 6周、双盲、安慰剂对照研究后 ,又进行了为期 2 6周的开放标记扩展临床研究 ,以评估其治疗轻到中重度阿尔茨海默病的有效性。结果表明 ,服用卡巴拉汀 6~ 1 2 mg/d共 5 2周的患者 ,认知功能明显好于以前服用安慰剂者。 | Martin Farlow Ravi Anand John Messina Jr Richard Hartman Jeffrey Veach 无 | 2002 | 中国神经免疫学和神经病学杂志2002，9，2： | 1 |
| 11 | HIV seroconversion manifesting as Guillian-Barre syndrome显示文摘To the editor:Human immunodeficiency virus (HIV) infection is an epidemic of modern era.Primary HIV infection usually presents as fever,fatigue,lymphadenopathy,myalgia,nausea and diarrhoea.Neurological symptoms may present during primary infection in 9% of patients usually as aseptic meningitis or opportunistic infections.The occurrence of Guillian-Barre syndrome (GBS) during seroconversion of HIV is rare.1 We report a case of patient who presented with acute onset quadriparesis diagnosed as acute inflammatory demyelinating polyneuropathy with simultaneous HIV positive with previous HIV negative status. | Ankur Nandan Varshney Ravi Anand Annesh Bhattacharjee Pratibha Prasad Nilesh Kumar N. K. Singh | 2014 | Chinese Medical Journal2014，，2： | 1 |
| 12 | The Kuznets process and the inequality -development relationship 显示文摘 | Anand Sudhir and Ravi Kanbur | 1993 | Journal of Development Economics1993，40，1993： | 1 |
| 13 | Differential fault location identification by machine learning显示文摘As the fault‐based attacks are becoming a more pertinent threat in today's era of edge computing/internet‐of‐things,there is a need to streamline the existing tools for better accuracy and ease of use,so that we can gauge the attacker's power and a proper countermeasure can be devised in the long run.In this regard,we propose a machine learning(ML)assisted tool that can be used in the context of a differential fault attack.In particular,finding the exact fault location by analysing the output difference(typically the XOR of the nonfaulty and the faulty ciphertexts)is somewhat nontrivial.During the literature survey,we notice that the Pearson's correlation coefficient dominantly is used for this purpose,and has almost become the defacto standard.While this method can yield good accuracy for certain cases,we argue that an MLbased method is more powerful in all the situations we experiment with.We sub-stantiate our claim by showing the relative performances(we choose the commonly used multilayer perceptron as our ML tool)with two variants of Grain‐128a(a stream cipher,and a stream cipher with authentication),the lightweight stream cipher LIZARD and the lightweight block cipher SIMON‐32(where the faults are injected at the fifth last rounds).Our results demonstrate that a common ML tool can outperform the correlation with the same training/testing data.We believe that our work extends the state‐of‐the‐art by showing how traditional cryptographic methods can be replaced by a more powerful ML tool. | Anubhab Baksi Santanu Sarkar Akhilesh Siddhanti Ravi Anand Anupam Chattopadhyay | 2021 | CAAI Transactions on Intelligence Technology2021，6，1： | 0 |
| 14 | Deep Learning-Based Model for Detection of Brinjal Weed in the Era of Precision Agriculture显示文摘The overgrowth of weeds growing along with the primary crop in the fields reduces crop production.Conventional solutions like hand weeding are labor-intensive,costly,and time-consuming;farmers have used herbicides.The application of herbicide is effective but causes environmental and health concerns.Hence,Precision Agriculture(PA)suggests the variable spraying of herbicides so that herbicide chemicals do not affect the primary plants.Motivated by the gap above,we proposed a Deep Learning(DL)based model for detecting Eggplant(Brinjal)weed in this paper.The key objective of this study is to detect plant and non-plant(weed)parts from crop images.With the help of object detection,the precise location of weeds from images can be achieved.The dataset is collected manually from a private farm in Gandhinagar,Gujarat,India.The combined approach of classification and object detection is applied in the proposed model.The Convolutional Neural Network(CNN)model is used to classify weed and non-weed images;further DL models are applied for object detection.We have compared DL models based on accuracy,memory usage,and Intersection over Union(IoU).ResNet-18,YOLOv3,CenterNet,and Faster RCNN are used in the proposed work.CenterNet outperforms all other models in terms of accuracy,i.e.,88%.Compared to other models,YOLOv3 is the least memory-intensive,utilizing 4.78 GB to evaluate the data. | Jigna Patel Anand Ruparelia Sudeep Tanwar Fayez Alqahtani Amr Tolba Ravi Sharma Maria Simona Raboaca Bogdan Constantin Neagu | 2023 | Computers, Materials & Continua2023，77，10： | 0 |
| 15 | Ataxia and arbovirus显示文摘To the editor:Dengue is a mosquito transmitted,newly emerging urban epidemic in tropical and subtropical countries.Usual symptoms are fever,headache,arthralgia and myalgia with severe prostration.Hemorrhagic manifestations as rash and thrombocytopenia are common.The two widely known,potentially fatal,complications are Dengue hemorrhagic fever and Dengue Shock Syndrome. | Ankur Nandan Varshney Ravi Anand Nilesh Kumar N. K. Singh | 2013 | Chinese Medical Journal2013，，18： | 0 |
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