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| 1 | 福林酚试剂法测定蛋白质显示文摘自1922年Wu(吴)提出用福林酚(Folin-酚)试剂测定蛋白质含量[1],已有许多采用这一试剂的改良分析操作进行血清陆”、抗原-抗体沉淀物[7-9]和胰岛素[10]中蛋白质含量测定的报道。虽然这一试剂以其灵敏度高和操作简便得到推荐,但并不适合普遍的生物化学应用。 | Lowry O H Rosebrough N J Farr A L Randall R J 陈祥娥 | 2011 | 食品与药品2011,13,3: | 34 |
| 2 | Significant association between ABO blood group and pancreatic cancer显示文摘AIM:To evaluate whether the ABO blood group is related to pancreatic cancer risk in the general population of the United States.METHODS:Using the University of Pittsburgh's clinicalpancreatic cancer registry,the blood donor database from our local blood bank (Central Blood Bank),and the blood product recipient database from the regional transfusion service (Centralized Transfusion Service) in Pittsburgh,Pennsylvania,we identified 274 pancreatic cancer patients with previously determined serological ABO blood group information.The ABO blood group frequency was compared between these patients and 708842 individual,community-based blood donors who had made donations to Pittsburgh's Central Blood Bank between 1979 and 2009.RESULTS:The frequency of blood group A was statistically significantly higher amongst pancreatic cancer patients compared to its frequency amongst the regional blood donors [47.63% vs 39.10%,odds ratio (OR)=1.43,P=0.004].Conversely,the frequency of blood group O was significantly lower amongst pancreatic cancer patients relative to the community blood donors (32.12% vs 43.99%,OR=0.60,P=0.00007).There were limited blood group B (n=38) and AB (n=17) pancreatic cancer patients;the overall P trend value comparing patient to donor blood groups was 0.001.CONCLUSION:The ABO blood group is associated with pancreatic cancer risk.Future studies should examine the mechanism linking pancreatic cancer risk to ABO blood group. | Julia B Greer Mark H Yazer Jay S Raval M Michael Barmada Randall E Brand David C Whitcomb | 2010 | World Journal of Gastroenterology2010,16,44: | 10 |
| 3 | Advancing research diagnostic criteria for Alzheimer’s disease: the IWG-2 criteria显示文摘 | Bruno Dubois Howard H Feldman Claudia Jacova Harald Hampel José Luis Molinuevo Kaj Blennow Steven T DeKosky Serge Gauthier Dennis Selkoe Randall Bateman Stefano Cappa Sebastian Crutch Sebastiaan Engelborghs Giovanni B Frisoni Nick C Fox Douglas Galasko Ma | 2014 | Lancet Neurology2014,,6: | 7 |
| 4 | Association between calcium sensing receptor gene polymorphisms and chronic pancreatitis in a US population:Role of serine protease inhibitor Kazal 1type and alcohol显示文摘AIM: To test the hypothesis that calcium sensing receptor (CASR) polymorphisms are associated with chronic pancreatitis (CP), and to determine whether serine protease inhibitor Kazal 1type (SPINK1) N34S oralcohol are necessary co-factors in its etiology. METHODS: Initially, 115 subjects with pancreatitis and 66 controls were evaluated, of whom 57 patients and 21 controls were predetermined to carry the high-risk SPINK1 N34S polymorphism. We sequenced CASR gene exons 2, 3, 4, 5 and 7, areas containing the majority of reported polymorphisms and novel mutations. Based on the initial results, we added 223 patients and 239 controls to analyze three common nonsynonymous single nucleotide polymorphisms (SNPs) in exon 7 (A986S, R990G, and Q1011E). RESULTS: The CASR exon 7 R990G polymorphism was signifi cantly associated with CP (OR, 2.01; 95% CI, 1.12-3.59; P = 0.015). The association between CASR R990G and CP was stronger in subjects who reported moderate or heavy alcohol consumption (OR, 3.12; 95% CI, 1.14-9.13; P = 0.018). There was no association between the various CASR genotypes and SPINK1 N34S in pancreatitis. None of the novel CASR polymorphisms reported from Germany and India was detected. CONCLUSION: Our United States-based study confirmed an association of CASR and CP and for the first time demonstrated that CASR R990G is a signifi cant risk factor for CP. We also conclude that the risk of CP with CASR R990G is increased in subjects with moderate to heavy alcohol consumption. | Venkata Muddana Janette Lamb Julia B Greer Beth Elinoff Robert H Hawes Peter B Cotton Michelle A Anderson Randall E Brand Adam Slivka David C Whitcomb | 2008 | World Journal of Gastroenterology2008,14,28: | 7 |
| 5 | Quality in the technical performance of colonoscopy and the continuous quality improvement process for colonoscopy: recommendations of the U.S. Multi-Society Task Force on Colorectal Cancer显示文摘 | Douglas K Rex John H Bond Sidney Winawer Theodore R Levin Randall W Burt David A Johnson Lynne M Kirk Scott Litlin David A Lieberman Jerome D Waye James Church John B Marshall Robert H Riddell | 2002 | The American Journal of Gastroenterology2002,,6: | 3 |
| 6 | Immunolocalization of H+-ATPase the gill epithelia of rainbow trout显示文摘 | Lin H Pfeiffer D Vogl A Pan J Randall D | 1994 | The Journal of experimental biology1994,195,1: | 1 |
| 7 | Protein measure- ment with the folin phenol reagent显示文摘 | LOWRY O H FARR A L RANDALL R J | 1951 | Journal of Biological Chemistry1951,193,1: | 1 |
| 8 | 1997 CEO perspectives on the current status and future prospects of the third party logistics industry in the United States显示文摘 | Lieb R C Randall H L | 1999 | Transportation Journal1999,,3: | 1 |
| 9 | Polyhydroxyalkanoates form potentially a key aspect of aerobic phosphorus uptake in enhanced biological phosphorus removal 显示文摘 | Randall A A Liu Y H | 2002 | Water Research2002,36,: | 1 |
| 10 | Application of a minimum entropy de- convolution filter to enhance Autoregressive model based geartooth fault detection technique 显示文摘 | Endo H Randall R B | 2007 | Mechanical Systems and Signal Processing2007,21,: | 1 |
| 11 | Demonstration of hormesis (increase in fatality rate)by penicillin显示文摘 | Randall W A Price C W Welch H | 1947 | American Journal of Public Health and the Nations Health1947,37,4: | 1 |
| 12 | Phase relations and dielectric properties in the Bi2O3-ZnO-Ta2O5 system显示文摘 | YOUN H J SOGABE T RANDALL C A | 2001 | J Am Ceram Soc2001,84,11: | 1 |
| 13 | Nitrate versus Oxygen Respiration in the Activated Sludge Process显示文摘 | McClintock S A Sherrard J H Novak J T Randall C W | 1988 | Journal WPCF1988,60,3: | 1 |
| 14 | The enhancement of fault detection and diagnosis in rolling element bearings using mini- mum entropy deconvolution combined, with spectral kurtosis 显示文摘 | Sawalhi N Randall R B Endo H | 2007 | Mechanical Systems and Signal Processing2007,21,: | 1 |
| 15 | A comparison of the use of third party logistics services by large American manufacturers显示文摘 | Lieb R C Randall H L | 1996 | Journal of Business Logistics1996,17,1: | 1 |
| 16 | The enhancementof fault detection and diagnosis in rolling element bear-ings using minimum entropy deconvolution combinedwith spectral kurtosis显示文摘 | Sawalhi N Randall R B Endo H | 2007 | Mechanical Systems andSignal Processing2007,21,: | 1 |
| 17 | J Chem Soc显示文摘 | Baggett N Buck K W Foster A B Randall M H Webber J M | 1965 | :33941965,,: | 1 |
| 18 | Primer- directed enzymatic amplification of DNA with a thermostable DNA polymerase 显示文摘 | Randall K Saiki RK David H | 1988 | Science1988,239,4839: | 1 |
| 19 | Basement Membrane and Connective Tissue Proteins in Early Lesions of Kaposi's Sarcoma As-sociated with AIDS显示文摘 | Randall H Kramer Aedm J | 1985 | The Journal of Investigative Dermatology1985,84,6: | 1 |
| 20 | Enhancement of autoregres- sire model based gear tooth fault detection technique by the use of minimum entropy deconvolution filter显示文摘 | ENDO H RANDALL R B | 2007 | Mechanical Systems and Signal Processing2007,21,2: | 1 |