|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Colonoscopy surveillance for high risk polyps does not always prevent colorectal cancer显示文摘AIM To determine the frequency and risk factors for colorectal cancer(CRC) development among individuals with resected advanced adenoma(AA)/traditional serrated adenoma(TSA)/advanced sessile serrated adenoma(ASSA). METHODS Data was collected from medical records of 14663 subjects found to have AA, TSA, or ASSA at screening or surveillance colonoscopy. Patients with inflammatory bowel disease or known genetic predisposition for CRC were excluded from the study. Factors associated with CRC developing after endoscopic management of high risk polyps were calculated in 4610 such patients who had at least one surveillance colonoscopy within 10 years following the original polypectomy of the incident advanced polyp. RESULTS84/4610(1.8%) patients developed CRC at the polypectomy site within a median of 4.2 years(mean 4.89 years), and 1.2%(54/4610) developed CRC in a region distinct from the AA/TSA/ASSA resection site within a median of 5.1 years(mean 6.67 years). Approximately, 30%(25/84) of patients who developed CRC at the AA/TSA/ASSA site and 27.8%(15/54) of patients who developed CRC at another site had colonoscopy at recommended surveillance intervals. Increasing age; polyp size; male sex; right-sided location; high degree of dysplasia; higher number of polyps resected; and piecemeal removal were associated with an increased risk for CRC developmentat the same site as the index polyp. Increasing age; right-sided location; higher number of polyps resected and sessile endoscopic appearance of the index AA/TSA/ASSA were significantly associated with an increased risk for CRC development at a different site. CONCLUSION Recognition that CRC may develop following AA/TSA/ASSA removal is one step toward improving our practice efficiency and preventing a portion of CRC related morbidity and mortality. | Mohamad A Mouchli Lidia Ouk Marianne R Scheitel Alisha P Chaudhry Donna Felmlee-Devine Diane E Grill Shahrooz Rashtak Panwen Wang Junwen Wang Rajeev Chaudhry Thomas C Smyrk Ann L Oberg Brooke R Druliner Lisa A Boardman | 2018 | World Journal of Gastroenterology2018，24，8： | 5 |
| 2 | Evaluation of anti-apoptotic activity of different dietary antioxidants in renal cell carcinoma against hydrogen peroxide显示文摘Objective:To evaluate the anti-apoptotic and radical scavenging activities of dietary phenolics, namely ascorbic acid,a-tocopherol acetate,citric acid,salicylic acid,and estimate H_2O_2induced apoptosis in renal cell carcinoma cells.Methods:The intracellular antioxidant potency of antioxidants was investigated.H_2O-2-induced apoptosis in RCC-26 was assayed with the following parameters:cell viability(%apoptosis),nucleosomal damage and DNA fragmentation, bcl-2 levels and flow cytometery analysis(ROS production evaluation).Results:Ine anticancer properties of antioxidants such as ascorbic acid,a- tocopherol acetate,citric acid,salicylic acid with perdurable responses were investigated.It was observed that these antioxidants had protective effect(anti-apoptotic activity) against hydrogen peroxide(H_2O_2) in renal cell carcinoma(RCC-26) cell line.Conclusions:This study reveals and proves the anticancer properties.However,in cancer cell lines anti-apoptotic activity can indirectly reflect the cancer promoter activity through radicals scavenging,and significantly protect nucleus and bcl-2. | Garg Neeraj K Mangal Sharad Sahu Tejram Mehta Abhinav Vyas Suresh P Tyagi Rajeev K | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，1： | 4 |
| 3 | Optically produced arrays of planar nanostructures inside fused silica显示文摘 | Bhardwaj V R Simova E Rajeev P P | | 0，，05： | 1 |
| 4 | Metal nano- plasmas as bright sources of hard X-ray pulses显示文摘 | Rajeev P P Taneja P Ayyub P | 2003 | Phys Rev Lett2003，90，11： | 1 |
| 5 | Polymerase chain reaction in clinically suspected genitourinary tuberculosis: comparison with intravenous urography, bladder biopsy, and urine acid fast bacilli culture显示文摘 | A.K Hemal N.P Gupta T.P Rajeev Rajeev Kumar L Dar P Seth | 2000 | Urology2000，，4： | 1 |
| 6 | Distributed optical fibre sensors and their applications in pipeline monitoring显示文摘 | Rajeev P Kodikara J Chiu W K | 2013 | Key Engineering Materials2013，558，： | 1 |
| 7 | Low tempera- ture electrical transport in Lal-x Ndx NiO3-8 显示文摘 | TIWARI A RAJEEV K P NARAYAN J | 2002 | Sol Stat Commun2002，121，67： | 1 |
| 8 | Ground-atmosphere Interaction Modelling for Long-term Prediction of Soil Moisture and Temperature显示文摘 | RAJEEV P CHAN D KODIKARA J | 2012 | Canadian Geotechnical Journal2012，49，9： | 1 |
| 9 | Magnetic properties of NiO nanoparticles 显示文摘 | Tiwari S D Rajeev K P | 2006 | Thin Solid Films2006，505，： | 1 |
| 10 | Chemotherapy Significantly Increases the Risk of Radiation Pneumonitis in Radiation Therapy of Advanced Lung Cancer显示文摘 | Bhupesh P Alison E Rajeev M | | 0，，02： | 1 |
| 11 | Therapeutic Silencing of an Endog e nous Gene by Systemic Administration of Modifi-ed SiRNAs显示文摘 | Soutschek J Akinc A Bramlage B Charisse K Constien R Donoghu e M Elba shir S Geick A Hadwiger P Harborth J John M Kesavan V Lavine G Pandey RK Racie T Rajeev KG Rohl I Toudjarska I Wang G Wuschko S Bumcrot D Kotelia nsky V Limmer S Manoharan M Vornlocher | | 0，，： | 1 |
| 12 | The number of positive lymph nodes in the central compartment has prognostic impact in papillary thyroid cancer 显示文摘 | Rajeev P Ahmed S Ezzat TM | 2013 | Langenbecks Arch Surg2013，398，3： | 1 |
| 13 | Recombinant OMP28 antigen-based indirect ELISA for serodiagnosis of bovine brucellosis显示文摘 | Pallab C Rajeev P Vinth K e? al | 2010 | Molecular and Cellular Prubes2010，24，： | 1 |
| 14 | Assessing solution quality of biob- jective 0 - 1 knapsack problem using evolutionary and heu- ristic algorithms 显示文摘 | RAJEEV K SINGH P K | 2010 | Applied Soft Computing2010，10，3： | 1 |
| 15 | Zingiber offi- cinale(ginger) as an anti-emetic in cancer chemotherapy: A review显示文摘 | Haniadka R Rajeev A G Palatty P L | 2012 | J Altern Complement Med2012，18，5： | 1 |
| 16 | Nonisothermal radio frequency drying of red oak 显示文摘 | Rajeev G J Graduate R J Perry N P | 2001 | Wood Fiber Science2001，33，3： | 1 |
| 17 | Inhibition of growth and metastasis of mouse mammary carcinoma by selective inhibitor of transforming growth factor-beta type I receptor kinase in vivo显示文摘 | Ge R Rajeev V Ray P | 2006 | Clin Cancer Res2006，12，141： | 1 |
| 18 | 显示文摘 | Rajeev K P Shivashanka G V Raychaudhuri A K | 1991 | Solid State Communication1991，79，7： | 1 |
| 19 | Low- temperature electronic properties of a normal conducting perovskite oxide (LaNiO3)显示文摘 | Shivashankar G V Raychaudhuri A K | 1991 | Solid State Commun1991，79，： | 1 |
| 20 | Solvothermal synthcsis and characterization of TiO2 nanocrystals with ultrahigh surface area显示文摘 | Rajeev K W Liu Y P Joshua C F | | 0，，02： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员