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| 1 | Appropriately adapted properties of hot-extruded Zn-0.5Cu-xFe alloys aimed for biodegradable guided bone regeneration membrane application显示文摘Appropriately adapted comprehensive mechanical properties,degradation behavior and biocompatibility are prerequisites for the application of Zn-based biodegradable implants.In this study,hot-extruded Zn-0.5Cu-xFe(x=0.1,0.2 and 0.4 wt%)alloys were fabricated as candidates for biodegradable materials for guided bone regeneration(GBR)membranes.The hot-extrusion process and Cu alloying were expected mostly to enhance the mechanical properties,and the Fe alloying was added mainly for regulating the degradation.The microstructure,mechanical properties and in vitro degradation behavior were systematically investigated.The ZnCuFe alloys were composed of a Zn matrix and FeZn13 phase.With increasing Fe content,a higher FeZn13 phase precipitation with larger particles was observed.Since elongation declined significantly until fracture with increasing Fe content up to 0.4 wt%,the ZnCuFe(0.2 wt%)alloy achieved a good balance between mechanical strength and ductility,with an ultimate tensile strength of 202.3 MPa and elongation at fracture of 41.2%.Moreover,the addition of Fe successfully accelerated the degradation of ZnCuFe alloys.The ZnCuFe(0.2 wt%)alloy showed relatively uniform corrosion in the long-term degradation test.Furthermore,extracts of the ZnCuFe(0.2 wt%)alloy showed no apparent cytotoxic effects against L929 fibroblasts,Saos-2 osteoblasts or TAg periosteal cells.The ZnCuFe(0.2 wt%)alloy exhibited the potential to inhibit bacterial adhesion of Streptococcus gordonii and mixed oral bacteria.Our study provides evidence that the ZnCuFe(0.2 wt%)alloy can represent a promising material for the application as a suitable GBR membrane. | Wentai Zhang Ping Li Gang Shen Xiaoshan Mo Chao Zhou Dorothea Alexander Frank Rupp Jürgen Geis-Gerstorfer Haijun Zhang Guojiang Wan | 2021 | Bioactive Materials2021，6，4： | 6 |
| 2 | The development of optical surfaces during the grinding pr ocess显示文摘 | | 1965 | Applied OPtics1965，4，6： | 1 |
| 3 | The S4-S5 linker directly couples voltage sensor movement to the activation gate in the human ether-a'-go-go-related gene (hERG) K+ channel显示文摘 | Ferrer T Rupp J Piper DR | 2006 | J Biol Chem2006，281，12： | 1 |
| 4 | Body fluid derived exosomes as a novel template for clinical diagnostics显示文摘 | KELLER S RIDINGER J RUPP A K | 2011 | J Translat Med2011，9，： | 1 |
| 5 | Tumor M2-pyruvate kinase: a promising tumor marker in the diagnosis of gastrointestinal cancer显示文摘 | Ngoumou BK Rupp J | 2000 | Anticancer Res2000，20，6： | 1 |
| 6 | The effect of needle type and immobilization headache显示文摘 | Hafer J Rupp D Wollbruok M | 1997 | Anaesthesist1997，6，3： | 1 |
| 7 | The Transcription Factors T-bet and Eomes Control Key Checkpoints of Natural Killer Cell Maturation显示文摘 | Gordon S M Chaix J Rupp L J | 2012 | Immunity2012，36，1： | 1 |
| 8 | Putting the S Back in Corporate Social Responsibility:A Multilevel Theory of Social Change in Organizations显示文摘 | Aguilera R.V Rupp D.E Williams C.A Ganapathi J | | 0，，03： | 1 |
| 9 | Tumor M2 - pyruvate kinase : a promising tumor marker in the diagnosis of gastro - intestinal cancer显示文摘 | Hardt PD Ngoumou BK Rupp J | 2000 | Anticancer Res2000，20，： | 1 |
| 10 | Use of continuous im- ulin infusion pumps in young children with type 1 diabetes: a systomatie review显示文摘 | Churchill J N Ruppe R L smaldone A | 2009 | J Pedialr Health Care2009，23，： | 1 |
| 11 | Body fluid derived exosomes as a novel template for clinical diagnostics显示文摘 | Keller S Ridinger J Rupp AK | 2011 | J Transl Med2011，9，： | 1 |
| 12 | Interactive textiles regulate body temperature显示文摘 | RUPP J | 1999 | International Textile Bulletin1999，45，1： | 1 |
| 13 | Be aware of the possibility of false-positive results in single-locus PCR assays for methicillin-resistant Staphylococcus aureus 显示文摘 | RUPP J FENNER I SOLBACH W | 2006 | J Clin Microbiol2006，44，6： | 1 |
| 14 | Large neutral amino acids block phenylalanine transport into brain tissue in patients with phenylketo- nuria显示文摘 | Pietz J Kreis R Rupp A | 1999 | J Clin In vest1999，103，8： | 1 |
| 15 | Impaired baroreceptor reflex sensitivity in acute stroke is associated with insular involvement,but not with carotid atherosclerosis显示文摘 | Sykora M Diedler J Rupp A | 2009 | Stroke2009，40，3： | 1 |
| 16 | Phagocytes transmit Chlamydia pneumoniae from the lungs to the vasculature显示文摘 | Gieffers J van Zandbergen Rupp J | 2004 | Eur Respir J2004，23，4： | 1 |
| 17 | Chlamydia pneumoniae infection promotes a proliferative phenotype in the vasculature through Egr-1 activation in vitro and in vivo显示文摘 | Rupp J Hellwig-Burgel T Wobbe V | 2005 | Proc Natl Acad Sci USA2005，102，9： | 1 |
| 18 | The failed back surgerysyndrome:reasons,intraoperative findings,and long-term results:a report of 182 operative treatments显示文摘 | FRITSCH EW HEISEL J RUPP S | 1996 | Spine1996，21，5： | 1 |
| 19 | PHR1 ,a pH-regulated gene of Candida albicans encoding a glu-can-remodelling enzyme, is required for adhesion and invasion显示文摘 | Calderon J Zavrel M Ragni E Fonzi W A Rupp S’Popolo L | 2010 | Microbiology2010，156，8： | 1 |
| 20 | Cox-2 inhibition abrogates Chlamydia pneumoniae-induced PGE2 and MMP-1 expression显示文摘 | Rupp J Berger M Reiling N | | 0，，03： | 1 |
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