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| 1 | Critical analysis of molluscicide application in schistosomiasis control programs in Brazil显示文摘In Brazil,Biomphalaria glabrata,B.tenagophila,and B.straminea are naturally infected by the trematode Schistosoma mansoni,the causative agent of schistosomiasis.Despite decades of governmental efforts through official control programs,schistosomiasis remains an important public health problem in the country:thousands of people are infected with the trematode each year and millions live in endemic areas.The World Health Organization recommends using a combination of molluscicide(niclosamide)and mass chemotherapy to control the transmission of schistosomiasis,with this treatment successfully reducing the morbidity of the disease.In the past,niclosamide has been used in official schistosomiasis control programs in Brazil.However,as B.glabrata recolonizes even after molluscicide application,the use of molluscicides has gradually decreased in the country until they were discontinued in 2002,mainly due to the rising global pressure to preserve the environment and the difficulties of obtaining licenses from the Brazilian Ministry of Environment to use toxic substances in aquatic ecosystems.Therefore,the discovery of new molluscicides,which could be more selective to Biomphalaria species and less harmful to the aquatic ecosystem,is necessary.In addition,political efforts to sensitize funders to provide grants for this field of research are required.In this context,this article aims to make a critical analysis of molluscicide application in schistosomiasis control programs in Brazil. | PMZ Coelho RL Caldeira | 2016 | Infectious Diseases of Poverty2016，5，1： | 4 |
| 2 | Proteome analy- sis of the cardiac and pericardial tissue of Biomphalaria tenagophila populations susceptible and resistant to Schistosoma mansoni infection 显示文摘 | Jannotti-Passos LK Andrade HM Caldeira RL | 2008 | Aeta Trop2008，105，3： | 1 |
| 3 | Phylogenetic relationships among Brazilian Biomphalaria species (Mollusca:Planorbidae) based upon analysis of ribosomal ITS2 sequences显示文摘 | Vidigal TH Kissinger JC Caldeira RL | 2000 | Parasitology2000，121，6： | 1 |
| 4 | Molecular of similar species of the genus Biomphalaria (Mollusca : Planorbidae) determined by a polymerase chain reaction-restriction fragment length polymorphism显示文摘 | Caldeira RL identification Vidigal TH Paulinelli ST | 1998 | Mem Inst Oswaldo Cruz1998，93，1： | 1 |
| 5 | Genetic variability and molecular identification of brazilian biomphalaria species 显示文摘 | Carvalho OS caldeira RL Simpson A J | 2001 | Parasi- tology2001，，： | 1 |
| 6 | Phylogenetic analysis of Biom- phalaria tenagophila (Orbigny, 1835) (Mollusca: Gastropoda) 显示文摘 | Passos LK Ruiz JC Caldeira RL | 2010 | Mem Inst Oswaldo Cruz2010，105，4： | 1 |
| 7 | Phylogenetic relation- ships among Brazilian Biomphalaria species (Mollusca: Planorbidae) based upon analysis of ribosomal ITS2 sequences 显示文摘 | Vidigal TH Kissinger JC Caldeira RL | 2000 | Parasitology2000，121，： | 1 |
| 8 | Genetic variabibility and molecular identification of Brazilian Biom phalaria species (Mollusca: Planorbidae) 显示文摘 | Carvalho S Caldeira RL Simpson AJ | 2001 | Parasitology2001，123，： | 1 |
| 9 | Genetic variability and molecular identification of Brazilian Biomphalaria species (Mollusca: Planorbidae)显示文摘 | Carvalho S Caldeira RL Simpson AJ | 2001 | Parasitology2001，，： | 1 |
| 10 | Sequencing of simple sequence repeat anchored polymerase chain reaction amplification products of Biomphalaria glabrata显示文摘 | Caldeira RL Carvalho OS Lage RC | 2002 | Mem Inst Oswaldo Cruz2002，97，1： | 1 |
| 11 | Phylogenetic relationships among Brazilian Biomphalaria species (Mollusca: Planorbidae) based upon analysis of ribosomal ITS2 sequences显示文摘 | Vidigal TH Kissinger JC Caldeira RL | 2000 | Parasitology2000，121，6： | 1 |
| 12 | Protcome analysis of the cardiac and pericardial tissue of Biomphalaria tenagophila populations susceptible and resistant to Schistosoma mansoni infection显示文摘 | Jannotti-Passos LK Andrade HM Caldeira RL | 2008 | Acta Trop2008，105，3： | 1 |
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