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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Muhidetector computed tomography of the renal arteries in vascular emergencies 显示文摘 | Regine G Stasolla A Miele V | 2007 | Eur J Radiol2007，64，： | 1 |
| 3 | Degradable biomaterials based on Magnesium corrosion 显示文摘 | Frank W Norbert H Carla V Smadar C Karl U K Regine W Frank F | 2008 | Current Opinion in Solid State and Materials Science2008，12，56： | 1 |
| 4 | Recovery of polyphenols from the by-products of plant food processing and application as valuable food ingredients显示文摘 | DIETMAR R K JUDITH K REGINE V | 2014 | Food Research International2014，，： | 1 |
| 5 | Comparison of different polymer-like structures in the confined geometry of foam films显示文摘 | REGINE V Klitzing ALEXANDRE Espert ANNIE Colin | 2001 | Colloids and Surfaces A:Physico Chemical andEngineering Aspecs2001，176，： | 1 |
| 6 | Epidemiology of humanimmunodeficiency virus infection in blood donations in Europe and Italy显示文摘 | Suligoi B Raimondo M Regine V | 2010 | Blood Transfus2010，8，3： | 1 |
| 7 | Epidemiology of human immunodeficiency virus infection in blood donations in Europe and Italy 显示文摘 | Suligoi B Raimondo M Regine V | 2010 | Blood Transfus2010，8，3： | 1 |
| 8 | Epidemiology of human immunodeficiency virus infection in blood donations in Europe and Italy显示文摘 | Suligoi B Raimondo M Regine V | 2010 | Blood Transfus2010，8，3： | 1 |
| 9 | Sexual behaviour reported by a sample of Italian MSM before and after HIV diagnosis 显示文摘 | Camoni L Dal Conte I Regine V | 2011 | Ann Ist Super Sanita2011，47，2： | 1 |
| 10 | Epidemiology of hu- man immunodeficiency virus infection in blood donations in Eu- rope and Italy显示文摘 | Suligoi B Raimondo M Regine V | 2010 | Blood Transfuse2010，8，3： | 1 |
| 11 | Second-generation sonographic contrast agents in the evaluation of renal trauma显示文摘 | Atzori M Miele V | 2007 | Radiol Med (Torino)2007，112，4： | 1 |
| 12 | Multidetector computed tomography of the renal arteries in vascular emergencies显示文摘 | Regine G Stasolla A Miele V | 2007 | Eur J Radiol2007，64，： | 1 |
| 13 | Epidemiology of human immunodeficiency virus infection in blood do- nations in Europe and Italy显示文摘 | Suligoi B Raimondo M Regine V | 2010 | Blood Transfus2010，8，3： | 1 |
| 14 | Identification of re- cent HIV infections and of factors associated with virus acquisi- tion among pregnant women in 2004 and 2006 in Swaziland显示文摘 | Bernasconi D Tavoschi L Regine V | 2010 | J Clin Virol2010，48，3： | 1 |
| 15 | Film stability control显示文摘 | REGINE V Klitzing HANS Joachim Müller | 2002 | Current Opinion in Colloid & Interface Science2002，，7： | 1 |
| 16 | Epidemiology of human immunodeficiency virus infection in blood dona- tions in Europe and Italy显示文摘 | Suligoi B Raimondo M Regine V | 2010 | Blood Transfus2010，8，3： | 1 |
| 17 | A nano-scale study on film stability显示文摘 | Regine V Klitzing Tieke B | | 0，，： | 1 |
| 18 | Highly efficient singlephase transformedess inverters for grid-connected photovoltaic systems显示文摘 | SAMUEL V A PETER Z REGINE M | | 0，，09： | 1 |
| 19 | Convergence of innate immunity and insulin resistance as evidenced by increased nucleo- tide oligomerization domain (NOD) expression and signaling in monocytes from patients with type 2 diabetes显示文摘 | Shiny A Regin B Balachandar V | 2013 | Cytokine2013，64，2： | 1 |
| 20 | Convergence of innate im- munity and insulin resistance as evidenced by increased nucleotide nli- gomerization domain ( NOD ) expression and signaling in monocytes from patients with type 2 diabetes显示文摘 | Shiny A Regin B Balachandar V | 2013 | Cytokine2013，64，2： | 1 |
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