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| 1 | Characterization of focal liver lesions with SonoVue~-enhanced sonography: International multicenter-study in comparison to CT and MRI显示文摘AIM: To evaluate in a multicenter study whether the sonographic characterization of focal liver lesions can be improved using SonoVueüà-enhancement; and to compare this method with computed tomography (CT) and magnetic resonance imaging (MRI). METHODS: One hundred and thirty four patients with one focal liver lesion detected in baseline ultrasound (US) were examined with conventional US, contrastenhanced US (n = 134), contrast-enhanced CT (n = 115) and/or dynamic contrast-enhanced MRI (n = 70). The lesions were classified as malignant, benign or indeterminate and the type of lesion was determined. The f inal diagnosis based on the combined information of all imaging examinations, clinical information and histology (n = 32) was used. Comparisons were made to see whether the addition of contrast-enhanced US led to the improvement of the characterization of doubtful focal liver lesions. RESULTS: In comparison with unenhanced US, SonoVue markedly improves sensitivity and specificity for the characterization (malignant/benign) of focal liver lesions. In comparison with CT and/or dynamic MRI, SonoVueüà -enhanced sonography applied for characterization of focal liver lesions was 30.2% more sensitive in the recognition of malignancy and 16.1% more specific in the exclusion of malignancy and overall 22.9% more accurate. In the subgroup with confirmative histology available (n = 30), sensitivity was 95.5% (CEUS), 72.2% (CT) and 81.8% (MRI), and specif icity was 75.0% (CEUS), 37.5% (CT) and 42.9% (MRI). The sensitivity and specif icity of CEUS for the identif ication of focal nodular hyperplasia (FNH) and hemangiomas was 100% and 87%, resulting in an accuracy of 94.5%. CONCLUSION: SonoVueüà-enhanced sonography emerges as the most sensitive, most specif ic and thus most accurate imaging modality for the characterization of focal liver lesions. | Hervé Trillaud Jean-Michel Bruel Pierre-Jean Valette Valérie Vilgrain Gérard Schmutz Raymond Oyen Wieslaw Jakubowski Jan Danes Vlastimil Valek Christian Greis | 2009 | World Journal of Gastroenterology2009，15，30： | 34 |
| 2 | Football injuries of the ankle: A review of injury mechanisms, diagnosis and management显示文摘Football is the most popular sport worldwide and is associated with a high injury rate, most of which are the result of trauma from player contact. Ankle injuries are among the most commonly diagnosed injuries in the game. The result is reduced physical activity and endurance levels, lost game time, and considerable medical cost. Sports medicine professionals must employ the correct diagnostic tools and effective treatments and rehabilitation protocols to minimize the impact of these injuries on the player. This review examines the diagnosis, treatment, and postoperative rehabilitation for common football injuries of the ankle based on the clinical evidence provided in the current literature. | Raymond J Walls Keir A Ross Ethan J Fraser Christopher W Hodgkins Niall A Smyth Christopher J Egan James Calder John G Kennedy | 2016 | World Journal of Orthopedics2016，7，1： | 5 |
| 3 | AHTN and HHCB show weak estrogenic-butno uterotrophic activity显示文摘 | Willem Seinen Josephine G Lemmen Raymond H HPieters et a1 | 1999 | Toxicology Letters1999，111，： | 1 |
| 4 | Estimation of common long-memory components in cointegrated systems 显示文摘 | Raymond W Geoffrey G | 1995 | Journal of Business and Economic Statistics1995，13，1： | 1 |
| 5 | Rickettsia-like organism infecting juvenile sea-bass Dicentrarchus labrax 显示文摘 | Raymond J C Plassiart G N | 1996 | Bull Eur Assoc Fish Pathol1996，16，： | 1 |
| 6 | Aggregates of scrapie-associated prion protcin induce the cell-free conversion of protease-sentitive prion protein to the protease-resistant state显示文摘 | Caughey B Kocisko D A Raymond G J | 1995 | Chem Biol1995，2，： | 1 |
| 7 | Endovascular treatment of unruptured aneurysms 显示文摘 | Roy D Milot G Raymond J | 2001 | Stroke2001，32，9： | 1 |
| 8 | Optimal Two-threshold Polices in an M/G/1 Queue With Two Vacation Types显示文摘 | Raymond G Vickson Michel J A Van Eenige | 1997 | Performance Evaluation1997，29，： | 1 |
| 9 | A non-linear theory of consolidation显示文摘 | DAVIES E H RAYMOND G P | 1965 | Geotechnique1965，15，2： | 1 |
| 10 | Evolution of Resistance to High Temperature in Ectotherms显示文摘 | Raymond B Huey Joel G K | 1993 | The American Naturalist1993，142，： | 1 |
| 11 | Endovascular treatment ofunruptured aneurysms 显示文摘 | Roy D Milot G Raymond J | 2001 | Stroke2001，32，9： | 1 |
| 12 | Endovascular treatment of unruptured aneurysms 显示文摘 | Roy D Milot G Raymond J | 2001 | Stroke2001，32，9： | 1 |
| 13 | Intramolecular energy transfer in pyrene bodipy molecular dyads and triads显示文摘 | Raymond Z Christine G Gilles U | 2005 | Chem Eur J2005，11，24： | 1 |
| 14 | A Non-linear Theory of Consolidation显示文摘 | Davis E H Raymond G P | 1965 | Geotechnique1965，15，2： | 1 |
| 15 | Future Perspectives for the Treatment of Pulmonary Arterial Hypertension显示文摘 | Hossein A. Ghofrani Robyn J. Barst Raymond L. Benza Hunter C. Champion Karen A. Fagan Friedrich Grimminger Marc Humbert Gérald Simonneau Duncan J. Stewart Carlo Ventura Lewis J. Rubin | 2009 | Journal of the American College of Cardiology2009，，1： | 1 |
| 16 | Direct oxidation of hydrocarbons in a solid-oxide fuel cell 显示文摘 | Seungdoo P John M V Raymond J G | 2000 | Nature2000，404，： | 1 |
| 17 | Draft1 , a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation 显示文摘 | Raymond C S Murphy M W O'Sullivan M G etal | 2000 | Genes Dev2000，14，20： | 1 |
| 18 | Productivity of wellsin vertically fractured damaged formations 显示文摘 | RAYMOND L R BINDER G G Jr | 1967 | Journalof Petroleum Technology1967，19，1： | 1 |
| 19 | Selective control ofSIRP-alpha-positive airway dendritic cell trafficking throughCD47 is critical for the development of T ( H ) 2-mediatedallergic inflammation显示文摘 | Raymond M Rubio M Fortin G | 2009 | J Allergy Clin Immunol2009，1246，： | 1 |
| 20 | The measurement of place attachment: Personal, community, and environmental connections 显示文摘 | Raymond C M Brown G Weber D | 2010 | Journal of Environmental Psychology2010，30，4： | 1 |
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