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| 1 | Feasibility study of computed vs measured high b-value(1400 s/mm2) diffusion-weighted MR images of the prostate显示文摘AIM: To evaluate the impact of computed b = 1400 s/mm2(C-b1400) vs measured b = 1400 s/mm2(M-b1400) diffusion-weighted images(DWI) on lesion detection rate, image quality and quality of lesion demarcation using a modern 3T-MR system based on a small-field-of-view sequence(sFOV). METHODS: Thirty patients(PSA: 9.5 ± 8.7 ng/mL; 68 ± 12 years) referred for magnetic resonance imaging(MRI) of the prostate were enrolled in this study. All measurements were performed on a 3T MR system.For DWI, a single-shot EPI diffusion sequence(b = 0, 100, 400, 800 s/mm2) was utilized. C-b1400 was cal-culated voxelwise from the ADC and diffusion images. Additionally, M-b1400 was acquired for evaluation and comparison. Lesion detection rate and maximum lesion diameters were obtained and compared. Image quality and quality of lesion demarcation were rated accord-ing to a 5-point Likert-type scale. Ratios of lesion-to-bladder as well as prostate-to-bladder signal intensity(SI) were calculated to estimate the signal-to-noise-ratio(SNR). RESULTS: Twenty-four lesions were detected on M-b1400 images and compared to C-b1400 images. C-b1400 detected three additional cancer suspicious lesions. Overall image quality was rated significantly better and SI ratios were significantly higher on C-b1400(2.3 ± 0.8 vs 3.1 ± 1.0, P < 0.001; 5.6 ± 1.8 vs 2.8 ± 0.9, P < 0.001). Comparison of lesion size showed no significant differences between C- and M-b1400(P = 0.22). CONCLUSION: Combination of a high b-value extrap-olation and sFOV may contribute to increase diagnostic accuracy of DWI without an increase of acquisition time, which may be useful to guide targeted prostate biopsies and to improve quality of multiparametric MRI(mMRI) especially under economical aspects in a pri-vate practice setting. | Leonardo K Bittencourt Ulrike I Attenberger Daniel Lima Ralph Strecker Andre de Oliveira Stefan O Schoenberg Emerson L Gasparetto Daniel Hausmann | 2014 | World Journal of Radiology2014，6，6： | 5 |
| 2 | Isolation and culture of adult mouse hepatocytes显示文摘 | Li W C Ralphs K L Tosh D | 2010 | Methods Mol Biol2010，633，： | 1 |
| 3 | Parallel branch,cut,and price for large-scale discrete optimization显示文摘 | RALPHS T K LADANYI L SALTZMAN M J | | 0，，1： | 1 |
| 4 | A library hierarchy for implementing scalable parallel search algorithms显示文摘 | RALPHS T K LADANYI L SALTZMAN M J | | 0，，02： | 1 |
| 5 | Incorporation of an isoleucine zipper motif enhances the biological activity of soluble CD40L (CD154) 显示文摘 | Arvia E M Richard L R Ralph K | 1999 | J Biol Chem1999，274，： | 1 |
| 6 | Function of phytochelatin synthase incatabolism of glutathione-conjugates显示文摘 | RALPH B ANDREAS B ARTHUR K ANNA S THOMAS L KLAUS L ERWIN G | 2007 | The Plant Journal2007，49，： | 1 |
| 7 | Locoweeds of North America l taxonomy and toxicity显示文摘 | Welsh S L Ralphs M H Panter K E | 2007 | Poisonous Plants:Global Research and Solutions2007，，： | 1 |
| 8 | Isolation and culture of adult mouse hepatocytes显示文摘 | LI Wanchun RALPHS K L TOSH D | 2010 | Methods Mol Biol2010，633，： | 1 |
| 9 | Radicality of parametrial resection and dysfunction of the lower urinary tract after radical hysterectomy显示文摘 | Winter R Michelitsch L Tamussino K | 1991 | Eur J Gynaecol Oncol1991，，： | 1 |
| 10 | Deep-hole geophone studies 显示文摘 | Franklyn K L Ralph D L | 1958 | Geophysics1958，23，4： | 1 |
| 11 | Hypertension and arterial stiffness: the atherosclerosis risk in communities study显示文摘 | Donna K Arnett Lori L Boland Gregory W Evans Ward Riley Ralph Barnes H.A Tyroler Gerardo Heiss | 2000 | American Journal of Hypertension2000，，4： | 1 |
| 12 | Exponential smoothing model selection for forecasting显示文摘 | Maxwell L K Ralph D | 2006 | International Journal of Forecasting2006，22，2： | 1 |
| 13 | Separation of metal- lic from semiconducting single-walled carbon nanotubes显示文摘 | Ralph K Frank H Hilbert V L | 2003 | Science2003，301，： | 1 |
| 14 | Decontamina- tion of aflatoxin B1 - contaminated corn by ammonium per- sulphate during fermentation 显示文摘 | ARMANDO B H RALPH L P KAREN J K | 2002 | J Sci Food Agric2002，82，： | 1 |
| 15 | Scene-referenced object localization显示文摘 | RALPH J F SIMS S W EDWARDS K L | 2004 | SPIE2004，，： | 1 |
| 16 | Isolation and culture of adult mouse hepatocytes显示文摘 | Li W C Ralphs K L Tosh D | 2010 | Methods Mol Biol2010，633，： | 1 |
| 17 | Keratinocyte serum-free medium maintains long-term liver gene expression and function in cultured rat hepatocytes by preventing the loss of liver-enriched transcription factors显示文摘 | Li W C Ralphs K L Slack J M W | 2007 | Int J Bioch Cell Biol2007，39，3： | 1 |
| 18 | NFIRE to TerraSAR X laser communication results satellite pointing,disturbances,and other attributes consistent with successful performance显示文摘 | Renny F Carl L Robert W Josef W David K John J Brian H Gerd M Wayne S Uwe S Ralph K Rolf M | 2009 | Proceedings of SPIE2009，7330，： | 1 |
| 19 | Altimetry-Derived Gravity Predictions of Bathymetry by the Gravity-Geologic Method显示文摘 | Jeong W K Ralph R B Bang Y L | | 0，，： | 1 |
| 20 | 查看详情显示文摘 | Lanyon B E Barbier M Almeida M E Jennewein T Ralph T C Resch K J Pryde G J O'Brien J L Gilchrist A White A G | | 0，，： | 1 |
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