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1篇 您的检索式：作者名="R.S.Lokhandae"

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		题名	作者	年代	出处	被引量
	1	Ultra-performance liquid chromatography electrospray ionization-tandem mass spectrometry method for the simultaneous determination of itraconazole and hydroxy itraconazole in human plasma显示文摘A highly sensitive,selective,and precise ultra-performance liquid chromatography tandem mass spectrometry method was developed and validated for simultaneous quantification of itraconazole and hydroxy itraconazole in human plasma by a single liquid-liquid extraction step.The precursor to product ion transitions of m/z 705.3/392.3.m/z 721.2/408.3 and m/z 708.2/435.4 were used to detect and quantify itraconazole,hydroxy itraconazole and itraconazole-d3 respectively.The lower limit of quantitation was found to be 0.500 ng/mL for itraconazole and 1.00 ng/mL for hydroxy itraconazole.The mean recoveries for itraconazole and hydroxy itraconazole were found to be 100.045% and 100.021%,respectively.This developed method with a chromatographic run time of 2.0 min was successfully applied to a bioequivalence study of 100 mg itraconazole capsule.	Ashish Dwivedi Bhupinder Singh Sandeep Sharma R.S.Lokhandae Naveen Dubey	2014	Journal of Pharmaceutical Analysis2014，4，5：	1

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