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| 1 | MicroRNAs are key regulators controlling iNKT and regulatory T-cell development and function显示文摘MicroRNAs(miRNAs)are an abundant class of evolutionarily conserved,small,non-coding RNAs that post-transcriptionally regulate expression of their target genes.Emerging evidence indicates that miRNAs are important regulators that control the development,differentiation and function of different immune cells.Both CD4^(+)CD25^(+)Foxp3^(+) regulatory T(Treg)cells and invariant natural killer T(iNKT)cells are critical for immune homeostasis and play a pivotal role in the maintenance of self-tolerance and immunity.Here,we review the important roles of miRNAs in the development and function of iNKT and Treg cells. | Li Zhou Jang-June Park Quanhui Zheng Zheng Dong Qingsheng Mi | 2011 | Cellular & Molecular Immunology2011，8，5： | 7 |
| 2 | Clinical practices s of Traditional Chinese Medicine for acute upper respiratory tract infection in children显示文摘OBJECTIVE:To develop Clinical practice s of Traditional Chinese Medicine(TCM) for acute upper respiratory tract infection(AURI) in children;TCM is usedalone or administered together with antibiotics.METHODS:Under the guidance of evidence-based medicine concept,in strict accordance with the rules of international s development,as well as on the basis of evidence of clinical research of TCM,the s solicited opinions from clinical experts and methodologists in TCM and Western Medicine.GRADE standard was applied to form experts' consensus.RESULTS:The s standardized classification of TCM patterns and TCM treatments in children with AURI,including prescription,Chinese patent medicine,non-drug treatment and prevention.CONCLUSION:Follows the principle of 'evidence based,consensus supplemented,and experience referred',these s were formulated,but the quality of evidence of included studies were relatively low.Further refinement of the s should be needed as deeper clinical studies as available in future. | Rong Ping Li Li Zhang Xilian Liu Quanhui Yan Huimin Xin Deli Xue Zheng Ren Xianqing Wu Zhenqi Ma Rong Zhang Junhua | 2018 | Journal of Traditional Chinese Medicine2018，38，4： | 7 |
| 3 | Active dry yeast supplementation improves the growth performance,rumen fermentation, and immune response of weaned beef calves显示文摘The objective of this experiment was to investigate the potential benefits of active dry yeast(ADY)on the growth performance,rumen fermentation,nutrient digestibility,and serum parameters of weaned beef calves.Thirty Simmental crossbred male calves(body weight=86.47±4.41 kg and 70±4 d of age)were randomly divided into 2 groups:control(CON)(fed basal ration)and ADY(fed basal ration and 5 g/d ADY per calf).The dietary concentrate-to-roughage ratio was 35:65.All the calves were regularly provided rations 3 times a day at 07:00,13:00,and 19:00 and had free access to wate r.The experiment lasted for 60 d.The average daily gain of ADY group was higher(P=0.007)than that of the CON group,and the ratio of feed intake to average daily gain in the ADY group was reduced(P=0.022)as compared to the CON group.The concentration of ruminal ammonia-N was higher(P=0.023)in the CON group than that in the ADY group,but an opposite trend of microbial protein was found between the 2 groups.Also,the ruminal concentrations of propionate and butyrate were higher(P<0.05)in the ADY group than those in the CON group.Calves fed ADY exhibited higher(P<0.05)crude protein and neutral detergent fiber digestibility.Supplementation of ADY increased(P<0.05)the contents of glucose,glutathione peroxidase,superoxide dismutase,immunoglobulin A,immunoglobulin M,and interleukin 10 in the serum of calves,but an opposite trend was observed in malondialdehyde,interleukin 1 beta,and tumor necrosis factor alpha contents between the 2 groups.In conclusion,dietary supplementation with ADY could improve the growth performance,rumen fermentation,nutrient digestibility,antioxidant ability,and immune response of weaned beef calves. | Jian Ma Cheng Wang Zhisheng Wang Guang Cao Rui Hu Xueying Wang Huawei Zou Kun Kang Quanhui Peng Bai Xue Lizhi Wang Yueming Zhu Xiaopeng Zhu | 2021 | Animal Nutrition2021，，4： | 7 |
| 4 | DOUBLE WAVE DESCRIPTION OF SINGLE PARTICLE IN AN INFINITELY DEEP SQUARE POTENTIAL WELL显示文摘Recently we have suggested that the state of a single particle should be jointly defined by two wave functions.In this letter we use this suggestion to discuss the motion of a single particle in an infinitely deep square potential well;the results obiained in the classical limit correctly describe the motion of the single particle with clarity. | HUANG Xiangyou QIAN Shangwu LIU Quanhui HE Zuoxiu | 1990 | Chinese Physics Letters1990，7，4： | 3 |
| 5 | Molecular characterization of methanogenic microbial communities for degrading various types of polycyclic aromatic hydrocarbon显示文摘Knowledge on methanogenic microbial communities associated with the degradation of polycyclic aromatic hydrocarbons(PAHs)is crucial to developing strategies for PAHs bioremediation.In this study,the linkage between the type of PAHs and microbial community structure was fully investigated through 16 S rRNA gene sequencing on four PAH-degrading cultures.Putative degradation products were also detected.Our results indicated that naphthalene(Nap)/2-methylnaphthalene(2-Nap),phenanthrene(Phe)and anthracene(Ant)sculpted different microbial communities.Among them,Nap and 2-Nap selected for similar degrading bacteria(i.e.,Alicycliphilus and Thauera)and methanogens(Methanomethylovorans and Methanobacterium).Nap and 2-Nap were probably activated via carboxylation,producing 2-naphthoic acid.In contrast,Phe and Ant shaped different bacterial and archaeal communities,with Arcobacter and Acinetobacter being Phe-degraders and Thiobacillus Ant-degrader.Methanogenic archaea Methanobacterium and Methanomethylovorans predominated Phe-degrading and Ant-degrading culture,respectively.These findings can improve our understanding of natural PAHs attenuation and provide some guidance for PAHs bioremediation in methanogenic environment. | Quanhui Ye Chengyue Liang Xunwen Chen Tingting Fang Yun Wang Hui Wang | 2019 | Journal of Environmental Sciences2019，31，12： | 3 |
| 6 | Optogenetics in neuroscience:what we gain from studies in mammals显示文摘Optogenetics is a newly-introduced technology in the life sciences and is gaining increasing attention.It refers to the combination of optical technologies and genetic methods to control the activity of specific cell groups in living tissue,during which high-resolution spatial and temporal manipulation of cells is achieved.Optogenetics has been applied to numerous regions,including cerebral cortex,hippocampus,ventral tegmental area,nucleus accumbens,striatum,spinal cord,and retina,and has revealed new directions of research in neuroscience and the treatment of related diseases.Since optogenetic tools are controllable at high spatial and temporal resolution,we discuss its applications in these regions in detail and the recent understanding of higher brain functions,such as reward-seeking,learning and memory,and sleep.Further,the possibilities of improved utility of this newly-emerging technology are discussed.We intend to provide a paradigm of the latest advances in neuroscience using optogenetics. | Quanhui Chen Ziling Zeng Zhian Hu | 2012 | Neuroscience Bulletin2012，28，4： | 2 |
| 7 | Comparative proteome analysis of alkaliphilic Bacillus sp.N16-5 grown on different carbon sources显示文摘To determine the impact of carbohydrates on the metabolic pathway in alkaliphiles, proteomes were obtained from cultures containing different carbohydrates and were resolved on two-dimensional gel electrophoresis (2-DE). The proteomes were compared to determine differentially expressed proteins. A novel alkaliphilic bacterium (alkaliphilic Bacillus sp. N16-5 isolated from Wudunur Soda Lake, China) was isolated in media with five different carbon sources (glucose, mannose, galactose, arabinose, and xylose). Comparative proteome analysis identified 61 differentially expressed proteins, which were mainly involved in carbohydrate metabolism, amino acid transport, and metabolism, as well as energy production and conversion. The comparison was based on the draft genome sequence of strain N16-5. The abundance of enzymes involved in central metabolism was significantly changed when exposed to various carbohydrates. Notably, catabolite control protein A (CcpA) was up-regulated under all carbon sources compared with glucose. In addition, pentose exhibited a stronger effect than hexose in CcpA-mediated carbon catabolite repression. These results provided a fundamental understanding of carbohydrate metabolism in alkaliphiles. | LI Gang SONG YaJian XUE YanFen RAO Lang ZHOU Chen WANG QuanHui MA YanHe | 2011 | Science China(Life Sciences)2011，54，1： | 2 |
| 8 | Characterization of a phenanthrene-degrading methanogenic community显示文摘Polycyclic aromatic hydrocarbons(PAHs)often occur in oil-contaminated soil,coke wastewater and domestic sludge;however,associated PAH degraders in these environments are not clear.Here we evaluated phenanthrene degradation potential in the mixed samples of above environments,and obtained a methanogenic community with different microbial profile compared to those from sediments.Phenanthrene was efficiently degraded(1.26 mg/L/d)and nonstoichiometric amount of methane was produced simultaneously.16S rRNA gene sequencing demonstrated that bacterial populations were mainly associated with Comamonadaceae Nocardiaceae and Thermodesulfobiaceae,and that methanogenic archaea groups were dominated by Methanobacterium and Methanothermobacter.Substances such as hexane,hexadecane,benzene and glucose showed the most positive effects on phenanthrene degradation.Substrate utilization tests indicated that this culture could not utilize other PAHs.These analyses could offer us some suggestions on the putative phenanthrene-degrading microbes in such environments,and might help us develop strategies for the removal of PAHs from contaminated soil and sludge. | Quanhui Ye Chengyue Liang Chongyang Wang Yun Wang Hui Wang | 2018 | Frontiers of Environmental Science & Engineering2018，12，5： | 2 |
| 9 | A multiple-reaction-monitoring mass spectrometric method for simultaneous quantitative analysis of five plasma apolipoproteins显示文摘A multiplexed targeted proteomic assay using a mTRAQ-MRM/MS-based approach was developed and assessed to systematically quantify the relative expressions of five candidate plasma apolipoproteins that have been previously shown to be dysregulated in neuropsychiatric disorders and cognitive dysfunction:apolipoprotein H(APOH),apolipoprotein J(APOJ),apolipoprotein A4(APOA4),apolipoprotein E(APOE),and apolipoprotein D(APOD).The peptides and transitions of each APO were carefully selected according to the tandem MS signals acquired on a TripleTOFTM 5600,followed by optimization of the declustering potential and collision energy voltages for transitions on a QTRAP 5500.Our results showed that the collision energies of mTRAQ-labeled peptides were approximately 15%–20%higher than corresponding non-labeled peptides.Through optimized transitions and parameters,we analyzed the relative abundances of the five APOs in human plasma with and without depletion of high abundant proteins.The results indicated that the MRM signals of four target APOs were significantly increased after depletion,while the MRM signal of one APO,APOD,was decreased.Furthermore,the relative abundances of the five target APOs in healthy human plasma were stable,and the ranking of these proteins according to their MS responses changed slightly.Therefore,we deduced that the rank order of the MS signals for these target proteins can be developed as a diagnostic signature for diseased plasma. | LI WenWen WANG QuanHui CHEN JianJun ZHOU Jian ZHOU XinYu XIE Peng | 2014 | Science China Chemistry2014，57，5： | 2 |
| 10 | Strain engineering the D-band center for Janus MoSSe edge: Nitrogen fixation显示文摘Nitrogen fixation is one of the most important and challenging process in production of ammonia at ambient temperature. We have first performed density function theory to propose the edge of Janus MoSSe(EJM) monolayer as a potential catalyst for nitrogen reduction reaction. Our results show that the superficial D-band centers play an important role in nitrogen fixation. The strain effects greatly alter the D-band center, and further change the interaction between the adsorbates and the surface of catalysts.Our findings provide a new thought into designing transition-metal chalcogenide catalysts for nitrogen fixation. | Xi Tang Zengxi Wei Quanhui Liu Jianmin Ma | 2019 | Journal of Energy Chemistry2019，28，6： | 2 |
| 11 | Isolation and Sequence Analysis of NSP2, ORF3 and ORF5 of PRRSV XH-GD Strain from Guangdong Province显示文摘The diseased samples collected from Guangdong Province were inoculated to Marc-145 cells,PRRSV-specific cytopathogenic effects( CPE) such as cell aggregation,cell shrinkage and cell exfoliation were observed and a PRRSV strain XH-GD was obtained. By using primers designed in accordance with the published gene sequences of PRRSV in GenBank,NSP2,ORF3 and ORF5 fragments were amplified by reverse transcription polymerase chain reaction and analyzed by sequence alignment. The results demonstrated that PRRSV strain XH-GD belonged to the North American genotype and the NSP2 gene contained discontinuous deletions of 30 amino acids. NSP2,ORF3 and ORF5 genes of XH-GD shared 83. 3%- 98. 9%,88. 6%- 99. 2% and 88. 1%- 99. 2% nucleotide homology,and76. 8%- 98. 3%,83. 7%- 98. 8% and 88. 1%- 99. 2% amino acid homology with HUB1,NX06,BJsy06,VR-2332,HB-1( sh) 2002,HB-2( sh) 2002,CH-la and RespPRRS MLV,respectively; however,NSP2,ORF3 and ORF5 genes of XH-GD shared only 52. 9%,65. 0% and 64. 3% nucleotide homology,and31. 3%,57. 5% and 58. 9% amino acid homology with LV,respectively. Phylogenetic analysis revealed that XH-GD had a closer relationship with HUB1,NX06,BJsy06,VR-2332,HB-1( sh) 2002,HB-2( sh) 2002,CH-la and RespPRRS MLV strains compared with LV strain. | Zongxi CAO Quanhui PAN Zhemin LIN Liuwu KONG Yimin HE Guihong ZHANG | 2014 | Agricultural Biotechnology2014，3，1： | 2 |
| 12 | Mi- croRNA miR-150 is involved in invariant NKT cell development and function显示文摘 | Quanhui Zheng Li Zhou Qing sheng Mi | 2012 | J Immunol2012，188，5： | 1 |
| 13 | Hydrothermal synthesis and photoluminescence of NaGd(MoO 4 ) 2 :Tb 3+ novel green phosphor显示文摘 | Jinsheng Liao Dan Zhou Hangying You He-rui Wen Quanhui Zhou Bin Yang | 2012 | Optik - International Journal for Light and Electron Optics2012，，： | 1 |
| 14 | Fabrication of superhydrophobic copper surface with ultra-low water roll angle显示文摘 | Zhang Youfa Yu Xinquan Zhou Quanhui | 2010 | Applied Surface Science2010，256，6： | 1 |
| 15 | The effects of addition of citric acid on the morphologies of ZnO nanorods 显示文摘 | Yang Zao Liu QuanHui Yang Lei | 2007 | Materials Research Bulletin2007，42，： | 1 |
| 16 | Electrochemical CO2 reduction over nitrogen-doped SnO2 crystal surfaces显示文摘Crystal planes of a catalyst play crucial role in determining the electrocatalytic performance for CO2 reduction.The catalyst SnO2 can convert CO2 molecules into valuable formic acid(HCOOH).Incorporating heteroatom N into SnO2 further improves its catalytic activity.To understand the mechanism and realize a highly efficient CO2-to-HCOOH conversion,we used density functional theory(DFT)to calculate the free energy of CO2 reduction reactions(CO2RR)on different crystal planes of N-doped SnO2(N-SnO2).The results indicate that N-SnO2 lowered the activation energy of intermediates leading to a better catalytic performance than pure SnO2.We also discovered that the N-Sn O2 (211)plane possesses the most suitable free energy during the reduction process,exhibiting the best catalytic ability for the CO2-to-HCOOH conversion.The intermediate of CO2RR on N-SnO2 is HCOO*or COOH* instead of OCHO*.These results may provide useful insights into the mechanism of CO2RR,and promote the development of heteroatomdoped catalyst for efficient CO2RR. | Yuefeng Zhang Jianjun Liu Zengxi Wei Quanhui Liu Caiyun Wang Jianmin Ma | 2019 | Journal of Energy Chemistry2019，28，6： | 1 |
| 17 | Formation and control of the surface defect in hypo-peritectic steel during continuous casting:A review显示文摘Hypo-peritectic steels are widely used in various industrial fields because of their high strength,high toughness,high processability,high weldability,and low material cost.However,surface defects are liable to occur during continuous casting,which includes depression,longitudinal cracks,deep oscillation marks,and severe level fluctuation with slag entrapment.The high-efficiency production of hypo-peritectic steels by continuous casting is still a great challenge due to the limited understanding of the mechanism of peritectic solidification.This work reviews the definition and classification of hypo-peritectic steels and introduces the formation tendency of common surface defects related to peritectic solidification.New achievements in the mechanism of peritectic reaction and transformation have been listed.Finally,countermeasures to avoiding surface defects of hypo-peritectic steels duiring continuous casting are summarized.Enlightening certain points in the continuous casting of hypo-peritectic steels and the development of new techniques to overcome the present problems will be a great aid to researchers. | Quanhui Li Peng Lan Haijie Wang Hongzhou Ai Deli Chen Haida Wang | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，12： | 0 |
| 18 | Dynamics of a Function Related to the Primes显示文摘Let n = p1p2 ··· pk, where pi(1 ≤ i ≤ k) are primes in the descending order and are not all equal. Let Ωk(n) = P(p1 + p2)P(p2 + p3) ··· P(pk-1+ pk)P(pk+ p1), where P(n) is the largest prime factor of n. Define w0(n) = n and wi(n) = w(wi-1(n)) for all integers i ≥ 1. The smallest integer s for which there exists a positive integer t such thatΩs k(n) = Ωs+t k(n) is called the index of periodicity of n. The authors investigate the index of periodicity of n. | Ying SHI Quanhui YANG | 2015 | Chinese Annals of Mathematics,Series B2015，36，1： | 0 |
| 19 | Benzene alkylation with long chain olefins catalyzed by ionic liquids:a review显示文摘The introduction of ionic liquids to alkylation process gives a choice for“green production”in the petrochemical and detergent industry.A lot of papers and patents have been published using chloroaluminate ionic liquid as a novel catalyst for alkylation with high reactivity and easy separation from reactants.These included the acidity,characterization,determination and catalysis technologies in batch and continuous operation mode for different scales.According to published data and several results of pilot alkylation,including the authors’experience,the prospect of chloroaluminate ionic liquids for commercials was also discussed.It has been pointed out that there still are many difficulties and challenges to be overcome for commercial application of the ionic liquid catalyst. | Congzhen QIAO Yonghong CAI Quanhui GUO | 2008 | Frontiers of Chemical Science and Engineering2008，2，3： | 0 |
| 20 | Ultrastructure and elemental composition of the eggshell of Reeve’s Pheasant(Syrmaticus reevesii)显示文摘The eggshell of Reeve’s pheasant(Syrmaticus reevesii)collected from the Dongzhai National Nature Reserve in Henan Province,China was studied.By using scanning electron microscopy and inductively coupled plasma(ICP)spectrometry,the ultrastructure and elemental composition of the eggshell was determined.The study showed that the average thickness of the surface layer of crys-tals,the palisade and cone layer,and the eggshell membrane were 20.8,220.8 and 62.5μm,respectively,accounting for 6.8%,72.6%and 20.6%of the total thickness of the eggshell.There were many vesicular holes in the palisade layer with an average diameter of 0.32±0.08μm(n=30).The function of these holes might be significant to air exchange.The shape of the eggshell pore on the surface layer of crystals is round or elliptical.The fracture surface of the pore is funnel-shaped.Some granules filled the upper part of the eggshell pores.The content of 21 elements in the eggshell of wild and captive Reeve’s pheasants was compared and presented.It indicated that among the elements that made up the eggshell of the wild pheasant,the content of Ca,Mg,P and S was much higher,ω>1 mg/g,withω(Ca)being higher than 40%of the eggshell.The contents of Na,Si,Sr,K and Al wereω=0.1-1 mg/g,while Fe,Zn,Pb,Mn,Cu,V and Ti had lower concentrations(ω=1-100μg/g).Theωof Ni,Cr,Co,Se,Cd were lower than 1μg/g.The elemental composition in the eggshell of the captive Reeve’s pheasant kept in the Dongzhai National Natural Reserve was significantly differ-ent from that of the wild species,with a difference of over 20%on S,Cu,Fe,Al,Mn,Si,Sr,Se and Cr.The lower intake of Fe,Mn,Si and Sr on the one hand and the higher intake of S,Cu,Al and Cr on the other hand might be responsible for the low fertility of captive Reeve’s pheasants in the Dongzhai National Nature Reserve.In order to ensure that the pheasants are receiving the proper amount of nutrition and to improve their breeding success,the amount of certain elements in the food should be adjusted. | CHANG Chongyan ZHANG Zhengwang CHEN Xiaoduan LIU Jinying SUN Quanhui | 2007 | Frontiers in Biology2007，2，3： | 0 |
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