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| 1 | Upper-gastrointestinal bleeding secondary to peptic ulcer disease:Incidence and outcomes显示文摘AIM:To evaluate the incidence,surgery,mortality,and readmission of upper gastrointestinal bleeding(UGIB)secondary to peptic ulcer disease(PUD).METHODS:Administrative databases identified all hospitalizations for UGIB secondary to PUD in Alberta,Canada from 2004 to 2010(n=7079)using the International Classification of Diseases Codes(ICD-10).A subset of the data was validated using endoscopy reports.Positive predictive value and sensitivity with 95%confidence intervals(CI)were calculated.Incidence of UGIB secondary to PUD was calculated.Logistic regression was used to evaluate surgery,in-hospital mortality,and 30-d readmission to hospital with recurrent UGIB secondary to PUD.Co-variants accounted for in our logistic regression model included:age,sex,area of residence(i.e.,urban vs rural),number of Charlson comorbidities,presence of perforated PUD,undergoing upper endoscopy,year of admission,and interventional radiological attempt at controlling bleeding.A subgroup analysis(n=6356)compared outcomes of patients with gastric ulcers to those with duodenal ulcers.Adjusted estimates are presented as odds ratios(OR)with95%CI.RESULTS:The positive predictive value and sensitivity of ICD-10 coding for UGIB secondary to PUD were85.2%(95%CI:80.2%-90.2%)and 77.1%(95%CI:69.1%-85.2%),respectively.The annual incidence between 2004 and 2010 ranged from 35.4 to 41.2 per100000.Overall risk of surgery,in-hospital mortality,and 30-d readmission to hospital for UGIB secondary to PUD were 4.3%,8.5%,and 4.7%,respectively.Interventional radiology to control bleeding was performed in 0.6%of patients and 76%of these patients avoided surgical intervention.Thirty-day readmission significantly increased from 3.1%in 2004 to 5.2%in 2010(OR=1.07;95%CI:1.01-1.14).Rural residents(OR rural vs urban:2.35;95%CI:1.83-3.01)and older individuals(OR≥65 vs<65:1.57;95%CI:1.21-2.04)were at higher odds of being readmitted to hospital.Patients with duodenal ulcers had higher odds of dying(OR=1.27;95%CI:1.05-1.53),requiring surgery(OR=1.73;95%CI:1.34-2.23),and being readmitted to hospital(OR=1.54;95%CI:1.19-1.99)when compared to gastric ulcers.CONCLUSION:UGIB secondary to PUD,particularly duodenal ulcers,was associated with significant morbidity and mortality.Early readmissions increased over time and occurred more commonly in rural areas. | Samuel Quan Alexandra Frolkis Kaylee Milne Natalie Molodecky Hong Yang Elijah Dixon Chad G Ball Robert P Myers Subrata Ghosh Robert Hilsden Sander Veldhuyzen van Zanten Gilaad G Kaplan | 2014 | World Journal of Gastroenterology2014，20，46： | 21 |
| 2 | Optimal linear cooperation for spectrum sensing in cognitive radio networks 显示文摘 | QUAN Z CUI SH G SAYED A H | 2008 | IEEE Selected in Signal Processing2008，2，1： | 1 |
| 3 | 显示文摘 | Quan X Yang S G Ruan X L | 2005 | Environ Sci Technol2005，39，： | 1 |
| 4 | A characterization for the dynamic recrystallization kinetics of as-extruded 7075 aluminum alloy based on true stress-strain curves显示文摘 | G Z Quan Y P Mao G S Li | | 0，，： | 1 |
| 5 | 查看详情显示文摘 | Xie G H Zhang Z S Xue Q Zhang S M Zhao L Luo Y Chen E Quan B F Zhao Y Liu S Y | | 0，，： | 1 |
| 6 | Isolation and particular expression of a new β-tubulin gene in wing discs during meta morphosis of Bombyxmori显示文摘 | Quan G X Kanke E Kawasaki H | 1998 | J Seric Sci Jpn1998，67，： | 1 |
| 7 | Wavelet analysis of speckle patterns with a temporal carrier显示文摘 | Yu F Cho J T Quan C G | 2005 | Applied Optics2005，44，95： | 1 |
| 8 | Simulating spatio- temporal dynamics of urbanization with multi-agent sys- tems a case study of the Phoenix Metropolitan Region, USA显示文摘 | TIAN G I OUYANG Y QUAN Q | 2011 | Ecological Modelling2011，222，5： | 1 |
| 9 | Ki-ras Mutation and p53 overexpression predict the clinical behavior of colorectal cancer:A southwest oncology group study显示文摘 | Ahnen DJ Feigl P Quan G | 1998 | Cancer Res1998，58，6： | 1 |
| 10 | A computational approach to assessing blast damage in urban centers using autodyna显示文摘 | COWLER M S QUAN X Y FAIRLIE G E | 2004 | American Society of Mechanical Engineers2004，418，： | 1 |
| 11 | Characterizing the HER2/neu status and metastatic potential of breast cancerstem/ progenitor ceils 显示文摘 | Pommier S J Quan G G Christante D Muller P New- ell A E Olson S B | 2010 | Ann Surg Oneol2010，17，： | 1 |
| 12 | Genome sequence of foxtail millet(Setaria italica)provides insights into grass evolution and biofuel potential显示文摘 | Zhang G Liu X Quan Z | 2012 | Nature Biotechnology2012，30，6： | 1 |
| 13 | Necessary optimality conditions and new optimization methods for cubic polynomial op- timization problems with mixed variables显示文摘 | Wu Z Y Quan J Li G Q | 2012 | Journal of Optimization Theory and Applications2012，153，： | 1 |
| 14 | Modeling, identification and control of a class of nonlinear system显示文摘 | Zhang H G Quan Y B | 2001 | IEEE Trans on Fuzzy Systems2001，9，2： | 1 |
| 15 | Binding constants of lead by humic and fulvic acids studied by anodic stripping square wave voltammetry显示文摘 | QUAN G X YAN J L | 2010 | Russian Journal of Electrochemistry2010，46，1： | 1 |
| 16 | The workability evaluation of wrought AZ80 magnesium alloy in hot compression 显示文摘 | QUAN G KUA T SONG W KANG B | 2011 | Materials & Design2011，32，4： | 1 |
| 17 | Dynamic equilibrium between cancer stem cells and non-stem cancer cells in human SW620 and MCF-7 cancer cell populations显示文摘 | Yang G Quan Y Wang W | 2012 | Br J Cancer2012，106，9： | 1 |
| 18 | Use-dependent inhibition of Na ^+ currents by Benzocaine homologs显示文摘 | Quan C Mok W M Wang G K | 1996 | Biophys J1996，70，1： | 1 |
| 19 | Theoretical and experimental correlations of gas dissolution, diffusion, and thermodynamic properties in determination of gas permeability and selectivity in supported ionic liquid membranes显示文摘 | QUAN G YIRAN Z ROONEY D | 2011 | Advances in Colloid and Interface Science2011，164，： | 1 |
| 20 | Image-based plant modeling 显示文摘 | Quan L Tan P Zeng G | 2006 | ACM Transactions on Graphics (Proceedings of SIC GRAPH '' 06)2006，25，3： | 1 |
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