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2篇 您的检索式:作者名="Qinyong Lin"
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1Regulation of shear stress on rolling behaviors of HL-60 cells on P-selectin显示文摘Circulating leukocytes in trafficking to the inflammatory sites, will be first tether to, and then roll on the vascular surface. This event is mediated through specific interaction of P-selectin and P-selectin glycoprotein ligand-1(PSGL-1), and regulated by hemodynamics. Poor data were reported in understanding P-selectin-mediated rolling. With the flow chamber technique, we herein observed HL-60 cell rolling on P-selectin with or without 3% Ficoll at various wall shear stresses from 0.05 to 0.4 dyn/cm2. The results demonstrated that force rather than transport regulated the rolling, similar to rolling on L- and E-selectin. The rolling was accelerated quickly by an increasing force below the optimal shear threshold of 0.15 dyn/cm2 first and then followed by a slowly decelerating phase starting at the optimum, showing a catch-slip transition and serving as a mechanism for the rolling. The catch-slip transition was completely reflected to the tether lifetime and other rolling parameters, such as the mean and fractional stop time. The narrow catch bond regime stabilized the rolling quickly, through steeply increasing fractional stop time to a plateau of about 0.85. Data presented here suggest that the low shear stress threshold serves as a mechanism for most cell rolling events through P-selectin.LING YingChen FANG Ying YANG XiaoFang LI QuHuan LIN QinYong WU JianHua 2014Science China(Physics,Mechanics & Astronomy)2014,57,10:4
2Dynamic Multi-Attribute Decision-Making Method with Double Reference Points and Its Application显示文摘To better reflect the psychological behavior characteristics of loss aversion,this paper builds a double reference point decision making method for dynamic multi-attribute decision-making(DMADM)problem,taking bottom-line and target as reference pints.First,the gain/loss function is given,and the state is divided according to the relationship between the gain/loss value and the reference point.Second,the attitude function is constructed based on the results of state division to establish the utility function.Third,the comprehensive utility value is calculated as the basis for alternatives classification and ranking.Finally,the new method is used to evaluate the development level of smart cities.The results show that the new method can judge the degree to which the alternatives meet the requirements of the decision-maker.While the new method can effectively screen out the unsatisfactory alternatives,the ranking results of other alternatives are consistent with those of traditional methods.Haoran Huang Qinyong Lin Weitong Chen Kai Fang Huazhou Chen Ken Cai 2021Computers, Materials & Continua2021,,7:0
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