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| 1 | Phytoplankton Assemblage of Yangtze River Estuary and the Adjacent East China Sea in Summer, 2004显示文摘巡航与包括生物、化学、物理的题目获得长江河口的学科交差的理解的意愿从迟了的 8 月被进行到 2004 年 9 月上旬。水样品分析显示全部的浮游植物种类丰富是 137。他们, 81 在 Bacillariophyta 和 48 inPyrrophyta 被发现,为 59.1% 和 35.0% 的财务分别地。房间许多表水取样的一般水准是 8.8 x 10 ~ 4 房间L^(有最大值的-1),, 102.9 x 10 ~ 4 房间L^(在区域遇到的-1)( 31.75 °N , 122.33 °E )并且最小, 0.2 x 10 ~ 4 房间L^(-1),在( 30.75 °N , 122.17 °E )。Thedominant 种类至多驻扎是 Skeletonema 肋前缘弦音器和 Proboscia alata f。有 0.35 和 0.27 的优势的 gracillima。竖直分布分析显示房间丰富和优势种的明显的层化在 5, 18 和 33 .Shannon 牛肉熏香肠索引的代表性的车站被发现,浮游植物集合的平均与房间丰富介绍了否定关联,与出现在的最佳(30.75 ° N, 122.67 ° E ) 。为在这个区域的浮游植物花蕾主要根据通过河量的环境变量,硝酸盐的提高的营养素,硅酸盐和磷酸盐的 PCAanalysis 负责。 | LUAN Qingshan SUN Jun SHEN Zhilian SONG Shuqun WANG Min | 2006 | Journal of Ocean University of China2006，5，2： | 22 |
| 2 | Measurement and Spatio-temporal Distribution of Urbanization Development Quality of Urban Agglomeration in China显示文摘Urbanization development quality(UDQ) of urban agglomeration(UA) is one of the important indexes to evaluate if the UA urbanization speed is reasonable,if the population urbanization process is sound,if the economic urbanization process is efficient,if the social urbanization process is harmonious and fair,which is generally composed of three parts,including economic urbanization development quality,social urbanization development quality and spa-tial urbanization security quality.With the research of evolution rules of UDQ,through the analysis on the interactive coordination relation between UDQ and urbanization level,the paper proposes three dimensional index ball and stan-dard value of comprehensive measures of UDQ,which is composed of three categories of indexes.By introducing At-kinson model,this paper constructs the sub-element measure model and segmental measure model of UDQ,and fur-ther makes an overall evaluation on the characteristic of UDQ of UAs in China.Results show that:1) UDQ of UAs lied at optimization and upgrading phase during 1995-2008 and the quality was low.Population urbanization level did not reflect the UDQ of UAs;2) the improving speed of the spatial urbanization security quality was higher than the so-cial urbanization development quality,and the improving speed of economic urbanization development quality was the lowest;3) the coordination between UDQ and urbanization level was not so good;4) there was a weak correlation re-lation between UDQ and UA scale,and it was not true that the bigger the UA was,the better the UDQ was. | WANG Deli FANG Chuanglin GAO Boyang HUANG Jinchuan YANG Qingshan | 2011 | Chinese Geographical Science2011，21，6： | 13 |
| 3 | Fra-1 protooncogene regulates IL-6 expression in macrophages and promotes the generation of M2d macrophages显示文摘肿瘤微型环境(TME ) 在肿瘤房间的生长起一个突出的作用。作为 TME 的主要煽动性的部件, M2d 巨噬细胞被 TME 教育以便他们采用支持肿瘤转移和前进的一个抑制免疫力的角色。有 6 月的 Fra-1 形式使活跃之物 protein-1 heterodimers 合伙并且驾驶基因抄写。Fra-1 被认为急速地导致 tumorigenesis 和前进。然而,在 M2d 巨噬细胞的产生的 Fra-1 的功能的角色糟糕迄今为止被理解。这里,我们表明那 4T1 乳房的癌房间与 RAW264.7 巨噬细胞房间 co 有教养,扭曲 RAW264.7 巨噬细胞房间区别进 M2d 巨噬细胞。4T1 房间在 RAW264.7 房间,然后 Fra-1 刺激 Fra-1 的 de novo overexpression 绑在 interleukin 6 (IL-6 ) 在 RAW264.7 房间增加 cytokine IL-6 的生产的倡导者。在 autocrine 的 IL-6 幕塑造扭曲 RAW264.7 巨噬细胞房间区别进 M2d 巨噬细胞。这些调查结果开的新卓见进怎么颠倒 M2d 导致巨噬细胞的有免疫力的忍耐改进 immunotherapeutic 途径的功效。 | Qingshan Wang Hong Ni Lan Lan Xiaoli Wei Rong Xiang Yue Wang | 2010 | Cell Research2010，20，6： | 12 |
| 4 | Design of Photobioreactors for Mass Cultivation of Photosynthetic Organisms显示文摘 | Qingshan Huang Fuhua Jiang Lianzhou Wang Chao Yang | 2017 | Engineering2017，3，3： | 12 |
| 5 | Influence of phase and microstructure on the rate of hydrochloric acid leaching in pretreated Panzhihua ilmenite显示文摘The present study investigated the influence of high temperature oxidation and reduction pretreatments on the leaching rate of Panzhihua ilmenite.The as-pretreated ilmenite was leached with 20%HCl at 105℃.The leaching process was controlled by the phases and microstructures that evolved during the pretreatment processes.The leaching kinetics of pure hematite,ilmenite and pseudobrookite were characterized to clarify the phase effect on the iron-leaching rate;the rate of iron leaching occurs in the following order in the HCl solution:hematite(ferric iron) > ilmenite(ferrous iron)>>pseudobrookite(ferric iron).Therefore,the often-cited notion that ferrous iron dissolves faster in HCl solutions than ferric iron when explaining the pretreatment effects is inaccurate.Moreover,the oxidation pretreatment(at 600-1000℃ for 4 h)cannot destroy the dense structure of the Panzhihua ilmenite.Therefore,the influence exerted by the oxidation on the leaching process is primarily determined by the phase change;oxidation at 600 and 700℃slightly increased the rate of iron leaching because the ilmenite was transformed into hematite,while the oxidation at 900-1000℃ significantly reduced the rate of iron leaching because a pseudobrookite phase formed.The reduction effect was subsequently investigated;the as-oxidized ilmenite was reduced under H_2 at 750℃ for 30 min.The reduction significantly accelerated the rate of subsequent iron leaching such that nearly all of the iron had dissolved after leaching for 2h in 20%HCl at 105℃.This enhanced iron-leaching rate is mainly attributed to the cracks and holes that formed during the reduction process. | Qingshan Zhu Jianbo Zhang Hongzhong Li | 2014 | Particuology2014，12，3： | 11 |
| 6 | GEOMETRICALLY NONLINEAR FINITE ELEMENT MODEL OF SPATIAL THIN-WALLED BEAMS WITH GENERAL OPEN CROSS SECTION显示文摘Based on the theory of Timoshenko and thin-walled beams,a new finite element model of spatial thin-walled beams with general open cross sections is presented in the paper,in which several factors are included such as lateral shear deformation,warp generated by nonuni-form torsion and second-order shear stress,coupling of flexure and torsion,and large displacement with small strain. With an additional internal node in the element,the element stiffness matrix is deduced by incremental virtual work in updated Lagrangian (UL) formulation. Numerical examples demonstrate that the presented model well describes the geometrically nonlinear property of spatial thin-walled beams. | Xiaofeng Wang Qingshan Yang | 2009 | Acta Mechanica Solida Sinica2009，22，1： | 11 |
| 7 | Comparison of microstructures and mechanical properties of composite extruded AZ31 sheets显示文摘The microstructures and mechanical properties of the composite extruded AZ31/AZ31 and AZ31/4047 Al sheets were investigated and made a comparison to the conventional extruded AZ31 sheet.Owing to the introduced intense shear deformation at the interface during the composite extrusion,grain refinement and tilted texture were detected in AZ31 layers of the AZ31/AZ31 and AZ31/4047 Al sheets,while the conventional extruded AZ31 sheet exhibited a relative coarse,inhomogeneous microstructure and strong basal texture.The compressiontension yield ratio was increased gradually from the AZ31 to the AZ31/AZ31 and AZ31/4047 Al sheets.Besides,the AZ31/4047 Al sheet could successfully accomplish the whole bending forming process at room temperature,while the AZ31 and AZ31/AZ31 sheets were both bend-formed to failure with significant cracks in the outer tensile region under the identical bending parameters.Moreover,under the same bending strain,both the outward offset degree of strain neutral layer and the sheet thickening were more serious in the AZ31/4047 Al composite sheet than those of the AZ31 and AZ31/AZ31 sheets.The foremost reason was the quite wide gap of material properties between Mg alloy AZ31 layer(tensile loading in the outer region)and Al 4047 layer(compressive loading in the inner region). | Yanfu Chai Yan Song Bin Jiang Jie Fu Zhongtao Jiang Qingshan Yang Haoran Sheng Guangsheng Huang Dingfei Zhang Fusheng Pan | 2019 | Journal of Magnesium and Alloys2019，7，4： | 11 |
| 8 | Influence of different extrusion processes on mechanical properties of magnesium alloy显示文摘AZ31 Mg alloy sheets were processed by the conventional symmetrical extrusion(CSE)and the asymmetric extrusion(ASE).Progressive-asymmetric extrusion(PASE)and severe strain-asymmetric extrusion(SASE)were employed for ASE processes.The texture at near-surface and mid-layer zones of ASE sheets was diverse penetrating the normal direction(ND).This was attributed to an additional asymmetric shear strain deformation during the ASE process.(0002)basal planes of PASE sheets tilt to the shear deformation direction.Meanwhile,the basal texture intensity of PASE sheets has been weakened compared with one in CSE sheets.Grain refinement and tilted weak basal texture obtained by SASE process dramatically enhances the room temperature strength and plasticity of the extruded AZ31 magnesium alloy sheets.The microstructure and mechanical responses were examined and discussed. | Qingshan Yang Bin Jiang Hucheng Pan Bo Song Zhongtao Jiang Jiahong Dai Lifei Wang Fusheng Pan | 2014 | Journal of Magnesium and Alloys2014，2，3： | 11 |
| 9 | Stability of twins in Mg alloys-A short review显示文摘In this article,the stability of twins,especially{10–12}twins,in Mg alloys was critically reviewed.In the last decade,pre-twinning is considered to be an effective method for adjusting the microstructure and properties of wrought Mg alloys.Especially,formation of twin-texture can remarkably improve formability of rolled Mg alloys.However,the stability of{10–12}twins determines the effect of this method.Previous work revealed that initial{10–12}twins may either grow or shrink under further deformation,and may be removed by static recrystallization under thermal effect.It is considered that improving the stability of twin structure could enhance the contribution of twin-texture on subsequent plastic formability.Based on this background,stress stability and thermal stability of{10–12}twin structure were summarized and reviewed in this article.Finally,a few critical scientific problems in this research field were pointed out.©2020 Published by Elsevier B.V.on behalf of Chongqing University. | Tingting Liu Qingshan Yang Ning Guo Yun Lu Bo Song | 2020 | Journal of Magnesium and Alloys2020，8，1： | 10 |
| 10 | Extraction, identification, and antioxidant property evaluation of limonin from pummelo seeds显示文摘Limonin, the main bioactive phytochemical constituent of limonoids with multi-functions, is enriched in citrus fruits and often found at a high concentration in citrus seeds. The present study was attempted to introduce a new and efficient extraction method to isolate limonoids from pummelo seeds, and to evaluate the antioxidant property of the main constituent limonin in Hep G2 cells. Three key single factors were identified for the extraction of limonoids from pummelo seeds using the Box-Behnken experiment design of response surface methodology(RSM), and the optimized extraction parameters were treatment with 89.68 m L of anhydrous acetone for 4.62 h at 78.94C, while the yield of limonoids was 11.52 mg/g. The structure of isolated main constituent of the limonoids was further identified as limonin by Fourier transform infrared(FT-IR) spectrometer and nuclear magnetic resonance(NMR)spectrum. Moreover, the molecular data in Hep G2 cells revealed that limonin exerted its anti-oxidant property mainly by the activation of nuclear factor(erythroid-2)-like 2(Nrf2)/kelch-like ECHassociated protein 1(Keap1)-antioxidant response element(ARE) pathway in the form of transcriptional regulation of Nrf2 m RNA and posttranscriptional regulation of Nrf2/Keap1 system. These results demonstrate that pummelo seeds are an ideal source of limonoids, and limonin is proved to exert its anti-oxidant property by the activation of Nrf2/Keap1 pathway. | Si Qin Chenghao Lv Qingshan Wang Zhibing Zheng Xi Sun Minyi Tang Fangming Deng | 2018 | Animal Nutrition2018，，3： | 10 |
| 11 | Nerve growth factor and injured peripheral nerve regeneration显示文摘Nerve growth factor (NGF) exhibits many biological activities,such as supply of nutrients,neuroprotection,and the generation and rehabilitation of injured nerves. The neuroprotective and neurotrophic qualities of NGF are generally recognized. NGF may enhance axonal regeneration and myelination of peripheral nerves,as well as cooperatively promote functional recovery of injured nerves and limbs. The clinical efficacy of NGF and its therapeutic potentials are reviewed here. This paper also reviews the latest NGF research developments for repairing injured peripheral nerve,thereby providing scientific evidence for the appropriate clinical application of NGF. | Endong Shi Bingchen Wang Qingshan Sun | 2008 | Neural Regeneration Research2008，3，11： | 10 |
| 12 | Spring migration duration exceeds that of autumn migration in Far East Asian Greater White-fronted Geese (Anser albifrons)显示文摘Background:Migration theory suggests,and some empirical studies show, that in order to compete for the best breeding sites and increase reproductive success,long-distance avian migrants tend to adopt a time minimization strategy during spring migration, resulting in shorter duration spring migration compared to that in autumn.Methods:Using GPS/GSM transmitters,we tracked the full migrations of 11 Greater White-fronted Geese (Anser albifrons) between southeast China and the Russian Arctic,to reveal the migration timing and routes of the East Asian population, and compare the difference in duration between spring and autumn migration of this population.Results:We found that migration in spring (79 ± 12 days) took more than twice as long to cover the same distance as in autumn (35 ±7 days).This difference in migration duration was mainly determined by significantly more time spent in spring (59±16 days) than in autumn (23± 6days) at significantly more stopover sites. Conclusions:We suggest that these geese, thought to be partial capital breeders, spent almost three quarters of total migration time at spring stopover sites to acquire energy stores for ultimate investment in reproduction, although we cannot reject the hypothesis that timing of the spring thaw also contributed to stopover duration.In autumn,they acquired necessary energy stores on the breeding grounds sufficient to reach Northeast China staging areas almost without stop, which reduced stopover times in autumn and resulted in the faster autumn migration than spring. | Xueqin Deng Qingshan Zhao Lei Fang Zhenggang Xu Xin Wang Haoren He Lei Cao Anthony David Fox | 2019 | Avian Research2019，10，3： | 9 |
| 13 | A NON-PARAMETER BAYESIAN CLASSIFIER FOR FACE RECOGNITION显示文摘A non-parameter Bayesian classifier based on Kernel Density Estimation (KDE)is presented for face recognition, which can be regarded as a weighted Nearest Neighbor (NN)classifier in formation. The class conditional density is estimated by KDE and the bandwidthof the kernel function is estimated by Expectation Maximum (EM) algorithm. Two subspaceanalysis methods-linear Principal Component Analysis (PCA) and Kernel-based PCA (KPCA)are respectively used to extract features, and the proposed method is compared with ProbabilisticReasoning Models (PRM), Nearest Center (NC) and NN classifiers which are widely used in facerecognition systems. The experiments are performed on two benchmarks and the experimentalresults show that the KDE outperforms PRM, NC and NN classifiers. | Liu Qingshan Lu Hanqing Ma Songde (Nat. Lab of Pattern Recognition, Inst. of Automation, Chinese Academy of Sciences, Beijing 100080) | 2003 | Journal of Electronics(China)2003，20，5： | 9 |
| 14 | A new drag model for TFM simulation of gas-solid bubbling fluidized beds with Geldart-B particles显示文摘In this work,a new drag model for TFM simulation in gas-solid bubbling fluidized beds was proposed,and a set of equations was derived to determine the meso-scale structural parameters to calculate the drag characteristics of Geldart-B particles under low gas velocities.In the new model,the meso-scale structure was characterized while accounting for the bubble and meso-scale structure effects on the drag coefficient.The Fluent software,incorporating the new drag model,was used to simulate the fluidization behavior.Experiments were performed in a Plexiglas cylindrical fluidized bed consisting of quartz sand as the solid phase and ambient air as the gas phase.Comparisons based on the solids hold-up inside the fluidized bed at different superficial gas velocities,were made between the 2D Cartesian simulations,and the experimental data,showing that the results of the new drag model reached much better agreement with experimental data than those of the Gidaspow drag model did. | Yingce Wang Zheng Zou Hongzhong Li Qingshan Zhu | 2014 | Particuology2014，12，4： | 8 |
| 15 | Direct reduction of hematite powders in a fluidized bed reactor显示文摘Ultrafine hematite powder was reduced to produce ultrafine iron powder in a 50%Ar-50%H_2 atmosphere at 450-550℃ in a fluidized bed reactor.The ultrafine hematite powder shows the typical agglomerating fluidization behavior with large agglomerates fluidized at the bottom of the bed and small agglomerates fluidized at the upper part of the bed.It was found that defluidization occurred even at the low temperature of 450℃ with low metallization rate.Defluidization was attributed mainly to the sintering of the newly formed iron particles.Granuation was employed to improve the fluidization quality and to tackle the defluidization problem,where granules fluidized like a Geldart's group A powder.Granulation was found to effectively reduce defluidization during reduction,without however sacrificing reduction speed.The asreduced iron powders from both the ultrafine and the granulated hematite exhibited excellent sintering activity,that is,fast sintering at temperature of as low as^580σ_(RR)~2),which is much superior as compared to that of nano/ultrafine iron powders made by other processes. | Qingshan Zhu Rongfang Wua Hongzhong Li | 2013 | Particuology2013，11，3： | 8 |
| 16 | IL-17 induces radiation resistance of B lymphoma cells by suppressing p53 expression and thereby inhibiting irradiation-triggered apoptosis显示文摘p53 是著名肿瘤 suppressor。然而,为在 B 淋巴瘤房间的 p53 表示的规章的机制,和在在肿瘤房间的辐射抵抗的开发的 p53 的可能的角色大部分是未知的。一根人的 B 淋巴瘤房间线, Karpas1106 (k1106 ) ,被用作辐射抵抗的一个模型。k1106 房间的 Apoptosis 用流动 cytometry 被决定。p53 的表示用实时 RT-PCR 并且西方的弄污被估计。结果证明在 8Gy 的那照耀在多达 40 % 导致了 apoptosis;k1106 房间。同时,照耀显著地增加了 k1106 房间的 IL-6 生产。当 k1106 房间是有规章的 T 房间(Tregs ) 的 cocultured 并且照耀时, apoptotic k1106 房间的率显著地被减少,显示到照耀的一个获得的电阻。从对待照耀的 k1106 房间导出的 IL-6 在 Tregs 导致了 IL-17 表示。IL-17 + Foxp3 + T 房间在 k1106 房间压制了 p53 表示。一起,照耀 k1106 房间在 Tregs 导致 IL-17 的表示,它在 k1106 房间防碍 p53 蛋白质的表示并且从而镇压在 k1106 房间的被触发照耀的 apoptosis。 | Qingshan Li Xin Xu Weijie Zhong Qinghua Du Bizhen Yu Huabao Xiong | 2015 | Cellular & Molecular Immunology2015，12，3： | 8 |
| 17 | NMDA Receptor Antagonist MK801 Protects Against 1-Bromopropane-Induced Cognitive Dysfunction显示文摘Occupational exposure to 1-bromopropane(1-BP) induces learning and memory deficits. However, no therapeutic strategies are currently available. Accumulating evidence has suggested that N-methyl-D-aspartate receptors(NMDARs) and neuroinflammation are involved in the cognitive impairments in neurodegenerative diseases. In this study we aimed to investigate whether the noncompetitive NMDAR antagonist MK801 protects against 1-BPinduced cognitive dysfunction. Male Wistar rats were administered with MK801(0.1 mg/kg) prior to 1-BP intoxication(800 mg/kg). Their cognitive performance was evaluated by the Morris water maze test. The brains of rats were dissected for biochemical, neuropathological,and immunological analyses. We found that the spatial learning and memory were significantly impaired in the1-BP group, and this was associated with neurodegeneration in both the hippocampus(especially CA1 and CA3)and cortex. Besides, the protein levels of phosphorylated NMDARs were increased after 1-BP exposure. MK801 ameliorated the 1-BP-induced cognitive impairments and degeneration of neurons in the hippocampus and cortex.Mechanistically, MK801 abrogated the 1-BP-induced disruption of excitatory and inhibitory amino-acid balance and NMDAR abnormalities. Subsequently, MK801 inhibited the microglial activation and release of pro-inflammatory cytokines in 1-BP-treated rats. Our findings, for the first time, revealed that MK801 protected against 1-BP-induced cognitive dysfunction by ameliorating NMDAR function and blocking microglial activation, which might provide a potential target for the treatment of 1-BP poisoning. | Lin Xu Xiaofei Qiu Shuo Wang Qingshan Wang Xiu-Lan Zhao | 2019 | Neuroscience Bulletin2019，35，2： | 8 |
| 18 | Texture control by {10-12} twinning to improve the formability of Mg alloys: A review显示文摘Texture control of wrought Mg alloys, particularly in rolled Mg alloy sheets, has been an important research topic for the past several decades because it has significant influence on stretch formability at room temperature. For Mg alloys, {10-12} twinning can be easily activated and causes a 86.3° lattice rotation. Thus, pre-twinning deformation is considered as an effective and low-cost method for texture control in wrought Mg and its alloys. Furthermore, it has been verified that texture control via pre-twinning deformation can remarkably improve stretch formability of rolled Mg alloy sheets. In this review, recent researches on texture control via twinning deformation and its influence on stretch formability will be critically reviewed. The main contents include the micro-mechanism and impact factors of control in twin-orientation, plastic processing techniques of pre-inducing twins and the application of pre-induced twins in improvement of stretch formability. Finally, further research directions on this field were proposed. | Bo Song Qingshan Yang Tao Zhou Linjiang Chai Ning Guo Tingting Liu Shengfeng Guo Renlong Xin | 2019 | Journal of Materials Science & Technology2019，35，10： | 8 |
| 19 | Progress of the satellite laser ranging system TROS1000显示文摘The mobile satellite laser ranging system TROS1000, successfully developed in 2010, achieves a high repetition rate and enables daytime laser ranging. Its measurement range has reached up to 36000 km with an accuracy as precise as 1 cm. Using recent observations in Wuhan, Jiufeng, Xianning, and Rongcheng, Shandong, we introduce the progress made using this mobile observation system. | Guo Tangyong Wang Peiyuan Li Xin Zhu Wei Zou Tong Li Shipeng Luo Qingshan | 2015 | Geodesy and Geodynamics2015，6，1： | 7 |
| 20 | CFD study on double-to single-loop flow pattern transition and its influence on macro mixing efficiency in fully baffled tank stirred by a Rushton turbine显示文摘For a fully baffled tank stirred by a Rushton turbine (RT), the flow pattern will change from double- to single-loop as the off bottom clearance (C) of the RT decreases from one third of the tank diameter. Such a flow pattern transition as well as its influence on the macro mixing efficiency was investigated via CFD simulation. The transient sliding mesh approach coupled with the standard k-s turbulence model could correctly and efficiently reproduce the reported critical C range where the flow pattern changes. Simulation results indicated that such a critical C range varied hardly with the impeller rotation speed but decreased significantly with increasing impeller diameter. Small RTs are preferable to generating the single-loop flow pattern. A mechanism of the flow pattern transition was further proposed to explain these phe no mena. The discharge stream from the RT deviates down wards from the horizontal direction for small C values;if it meets the tank wall first, the double-loop will form;if it hits the tank bottom first, the single-loop will form. With the flow pattern transition, the mixing time decreased by about 35% at the same power input (P), indicating that the single-loop flow pattern was more efficient than the double-loop to enhance the macro mixing in the tank. A comparison was further made between the single-loop RT and pitched blade turbine (PBT, 45°) from macro mixing perspective. The single-loop RT was found to be less efficient than the PBT and usually required 60% more time to achieve the same level of macro mixing at the same P. | Quanhong Zhu Hang Xiao Aqiang Chen Shujun Geng Qingshan Huang | 2019 | Chinese Journal of Chemical Engineering2019，27，5： | 6 |
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