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1篇 您的检索式:作者名="Qiangda CHEN"
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1Basophils as a potential therapeutic target in cancer显示文摘Basophils,which are considered as redundant relatives of mast cells and the rarest granulocytes in peripheral circulation,have been neglected by researchers in the past decades.Previous studies have revealed their vital roles in allergic diseases and parasitic infections.Intriguingly,recent studies even reported that basophils might be associated with cancer development,as activated basophils synthesize and release a variety of cytokines and chemokines in response to cancers.However,it is still subject to debate whether basophils function as tumor-protecting or tumor-promoting components;the answer may depend on the tumor biology and the microenvironment.Herein,we reviewed the role of basophils in cancers,and highlighted some potential and promising therapeutic strategies.Jicheng ZHANG Hanlin YIN Qiangda CHEN Guochao ZHAO Wenhui LOU Wenchuan WU Ning PU 2021Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021,22,12:0
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