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| 1 | Studies on Lung Cancer Angiogenesis-Application of Interventional Therapy (A Report of 56 Cases)显示文摘OBJECTIVE To investigate the significance of angiogenesis of lung cancer, in order to provide a scientific basis for interventional therapy. METHODS Double-phase enhancementscanning spiral CT and DSA were performed in 56 pathologically confi rmed lung cancer cases, in order to evaluate angiogenesis of the tumors. The patients included 36 males and 20 females, with ages ranging from 33 to 76 years (average of 53). Assessments and indexes for SCT and DSA examinations were as follows: a) Peak value (PV) of the cancerous focus was the difference between the maximum CT value after enhancement and the CT value of a plain scan; b) The abnormally distorted and expanded new vessels of the cancerous focus which could be macroscopically discriminated; c) DSA staining of the focus of cancer was sparse, grid-like and dense. Chemotherapy and embolotherapy via the bronchial artery (interventional therapy) were conducted. Radiotherapy was added for some of the solid tumors with a diameter exceeding 4 cm. RESULTS a) There were 25 cases with a central-type lesion, among which 4 were small cell lung cancers (SCLC) and 21 non-small cell lung cancers (NSCLC). The cases with a peripheral location accounted for 31 of the total, with a maximum diameter of 1.5 to 13.5 cm and a median of 4.2 cm, including 5 small cell lung cancers and 26 NSCLC cases. b) The reinforced PVs of the cancerous foci were as follows: The PV ranged from 45 to 70 Hu in 34 cases, 25 to 45 Hu in 19, and 10 to 25 Hu in 3. Sparse DSA staining occurred in 3 cases, there was uneven grid-like staining in 22 and dense staining in 31; c) The interventional therapy via the bronchial artery was con-ducted twice in 5 cases with the SCLC, and three times in 4 SCLC cases. For 3 of the latter cases, a dose of 5,000 to 7,000 cGy radiation therapy was added during the interventional treatment. Complete remissions (CR) were seen in 88.9% of the cases (8/9) and partial remission (PR) in 11.1% (1/9). Interventional therapy was conducted twice in 8 cases with NSCLC and three times in 30 with NSCLC and four times in 9 cases. Among the total cases, 13 received radiotherapy during interventional therapy, with a radiation dose of 5,000-7,000 cGy; The CR rate was 78.7% (37/47), PR was 14.9% (7/47) and the rate of non-remission was 6.4% (3/47). CONCLUSION Using imaging technology, analysis of angiogenesis of lung cancers was employed to accurately detect and quantify angiogenesis. This analysis was combined for interventional therapy, using embolizing agents and large doses of the anti-tumor drugs and angiogenesis inhibitors. The agents were selectively delivered into the tumor vessels to eliminate the primary tumor, in order to depress distant metastases and thus enhance the curative effect of the therapy. | Qiang Zhang Jun Guo Hailong Qian Baoqi Shi Jigang Zhang Chunjing Li Ailing Yang Zhuang Tian Baotou No. 7 Hospital Department of Radiol-ogy, Baotou Cancer Hospital, Baotou 014030, Inner Mongolia Autonomous Region, China. | 2007 | Chinese Journal of Clinical Oncology2007，4，1： | 5 |
| 2 | Prevention of Mother-To-Child Transmission of HIV-China,2011-2020显示文摘ABSTRACT Introduction:Prevention of mother-to-child transmission(PMTCT)of human immunodeficiency virus(HIV)is a global health focus in most parts of the world.The World Health Organization(WHO)launched the dual Elimination of Mother-to-Child Transmission(EMTCT)of HIV and syphilis initiative and released global guidance on criteria and processes for validation of the EMTCT in 2014.The purpose of this report was to analyze the key validation indicators of EMTCT of HIV in China from 2011 to 2020 and to provide relevant basis information for the implementation of EMTCT action in China. | Xiaoyan Wang Qian Wang Changhe Wang Tong Zhang Zhixin Li Zhonghua Ma Ailing Wang | 2021 | China CDC weekly2021，3，48： | 3 |
| 3 | Screening and Treatment of Syphilis for Pregnant Women—China,2011−2018显示文摘What is already known on this topic?The national program of prevention of mother-to-child transmission(PMTCT)of syphilis was initiated in 2011 and scaled to a national level since 2015.A better understanding of the implementation and outcomes of the program on PMTCT of syphilis is needed for future strategies to achieve the World Health Organization(WHO)goal of elimination of motherto-child transmission(EMTCT)of syphilis.What is added by this report Between 2011 and 2018,as the coverage of syphilis screening of pregnant women and treatment for syphilis-seropositive pregnant women and their infants have increased consistently,the incidence of congenital syphilis was significantly reduced from 91.6 cases per 100,000 live births to 18.4 cases per 100,000.Treatment rates and adequate treatment rates of syphilis-seropositive pregnant women were below the criteria of validation of EMTCT of syphilis and regional disparities were found.What are the implications for public health practice?We recommend continuing to strengthen the current PMTCT intervention strategies with further commitments to achieve the targets set by the WHO’s dual EMTCT of HIV and syphilis.Barriers to achieving high coverage of adequate treatment should be investigated and addressed at the provincial level to ensure prompt treatment for syphilis-seropositive pregnant women. | Yaping Qiao Xiaoyan Wang Qian Wang Zhen Li Xi Jin Ailing Wang | 2020 | China CDC weekly2020，2，26： | 2 |
| 4 | A Modularity Analysis Method for Forum Situation Prediction显示文摘A forum is a social network that consists of posters and the following comments made by netizens. Generally speaking, forum topics are evolving over time dynamically. In this paper, based on time series analysis and matrix modularity analysis, a novel prediction method is proposed through investigating the correlating influence of three key measurements: relationship strength, pillars, and change frequency of a forum topic. The method demonstrates that there exist some macroscopic and potential laws for forum situation prediction. Extensive experiments over large many datasets show the efficiency and effectiveness of the algorithms. | QIAN Ailing QU Binbin LU Yansheng HUANG Jin | 2011 | Wuhan University Journal of Natural Sciences2011，16，2： | 1 |
| 5 | Recommend Guideline on Prevention of Mother-to-Child Transmission of HIV in China in 2020显示文摘In China, a pilot project for the prevention of mother-to-child transmission (PMTCT) of the HIV was initiated in 2001. For the PMTCT of HIV, the Chinese government has released versions of the guidelines since 2004. In 2014, the World Health Organization released guidance on global processes and criteria for the validation of elimination of mother-to-child transmission of HIV and syphilis. To promote the elimination of mother-to-child transmission of HIV, syphilis, and hepatitis B virus in China, the Chinese government updated the Guideline for PMTCT of HIV, Syphilis, and Hepatitis B in 2020 (briefly as Guideline-2020). The Guideline-2020 comprises 5 parts: goals, interventions, support measures, duties and cooperation of departments, and definition indicators for PMTCT of HIV and corresponding calculation formulas. Compared with the previous versions, the key points updated in the Guideline-2020 are that the goals are set again, and health education and promotion, the procedure of HIV testing for pregnant women, and the antiretroviral therapy regimen for HIV-positive pregnant women and antiretroviral) prophylaxis regimen for infants are all updated. The antiretroviral prophylaxis regimen as zidovudine-lamivudine-nevirapine/lopinavir/ritonavir twice per day for 6 weeks is recommended for infants at high exposure risk to HIV, whereas the third antiretroviral therapy regimen as tenofovir-lamivudine-lopinavir/ritonavir is recommended for HIV-positive pregnant women, and indicators for PMTCT of HIV and corresponding calculation formulas are defined. | Shuiling Qu Qian Wang Xiaoyan Wang Yaping Qiao Jun Yao Zhen Li Xi Jin Zhixin Li Ailing Wang | 2023 | Infectious Diseases & Immunity2023，3，2： | 0 |
| 6 | Detection and Associated Factors for Cervical Precancerous Lesions Among HIV-Positive Women from High HIV-Burden Areas — China, 2015−2016显示文摘Summary What is already known about this topic?Cervical cancer is one of the most common cancers among HIV-positive women.The World Health Organization(WHO)has recommended a program of cervical cancer screening for HIV-positive women.Prospective follow-up studies and specific recommendations on cervical cancer screening for HIV-positive women in China are not currently being performed. | Yaping Qiao Ailing Wang Xiaoyan Wang Qian Wang Liwen Fang Linhong Wang | 2020 | China CDC weekly2020，2，20： | 0 |
| 7 | Homogeneous Einstein-like metrics on symmetric spaces显示文摘In this paper, we study homogeneous Einstein-like metrics on the compact irreducible symmetric space M, which is not isometric to a compact Lie group and has rank greater than 1. Whenever there exists a closed proper subgroup G′ of G = Isom_0(M) acting transitively on M, we find all the G′-invariant A-metrics and B-metrics on M. More precisely, we prove that G′-invariant metrics on M must be A-metrics, and G′-invariant B-metrics on M are always Einstein. | Chao Qian Ail Wu | 2021 | Science China Mathematics2021，64，5： | 0 |
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