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19篇 您的检索式:作者名="QASEM S"
    题名 作者 年代 出处 被引量
1Systematic review and meta-analysis on the association of tuberculosis in Crohn's disease patients treated with tumor necrosis factor-α inhibitors(Anti-TNFα)显示文摘AIM To perform a meta-analysis on the risk of developing Mycobacterium tuberculosis(TB) infection in Crohn's disease(CD) patients treated with tumor necrosis factoralpha(TNFα) inhibitors.METHODS A meta-analysis of randomized, double-blind, placebocontrolled trials of TNFα inhibitors for treatment of CD in adults was conducted. Arcsine transformation of TB incidence was performed to estimate risk difference. A novel epidemiologically-based correction(EBC) enabling inclusions of studies reporting no TB infection cases in placebo and treatment groups was developed to estimate relative odds.RESULTS Twenty-three clinical trial studies were identified, including 5669 patients. Six TB infection cases were reported across 5 studies, all from patients receiving TNFα inhibitors. Eighteen studies reported no TB infection cases in placebo and TNFα inhibitor treatment arms. TB infection risk was significantly increased among patients receiving TNFα inhibitors, with a risk difference of 0.028(95%CI: 0.0011-0.055). The odds ratio was 4.85(95%CI: 1.02-22.99) with EBC and 5.85(95%CI: 1.13-30.38) without EBC.CONCLUSION The risk of TB infection is higher among CD patients receiving TNFα inhibitors. Understanding the immunopathogenesis of CD is crucial, since using TNFα inhibitors in these patients could favor mycobacterial infections, particularly Mycobacterium avium subspecies paratuberculosis, which ultimately could worsen their clinical condition.Brent L Cao Ahmad Qasem Robert C Sharp Latifa S Abdelli Saleh A Naser 2018World Journal of Gastroenterology2018,24,25:4
2Indicators of biofilm development and activity in constructed wetlands microcosms显示文摘Ragusa S R McNevin D Qasem S 2004Water Research2004,38,:1
3Radial basis function network based on time variantmulti-objective particle swarm optimization for medical diseasesdiagnosis显示文摘Qasem S N Shamsuddin S M 2011Applied Soft Computing2011,11,1:1
4Loading magnetic nanoparticles into sperm cells does not affect their functionality显示文摘Makhluf S B D Qasem R Rubinstein S 2006Langmuir2006,22,94:1
5Multi-objective hybrid evolutionary algorithms for radial basis function neural network design 显示文摘QASEM S N SHAMSUDD1N S M ZAIN A M 2012Knowledge-Based Systems2012,27,1:1
6Indicators of Biofilm Development and Activity in Constructed Wetlands Microcosms显示文摘RAGUSA S MCNEVIN D QASEM S 2004Water research2004,38,12:1
7In-situ observation of deep water corals in the northern Red Sea waters of Saudi Arabia显示文摘QURBAN M A KRISHNAKUMAR P K JOYDAS T V MANIKANDAN K P ASHRAF T T M QUADRI S 1 WAFAR M QASEM A CAIRNS S D 2014Deep Sea Research Part I: Oceanographic Research Papets2014,89,:1
8Indicators of biofilm development and activity in constructed wetlands microcosms显示文摘S.R Ragusa D McNevin S Qasem C Mitchell 2004Water Research2004,,12:1
9Radial basis function network based on time variant multi-objective particle swarm optimization for medical diseases diagnosis 显示文摘Qasem S N Shamsuddin S M 2011Applied Soft Computing2011,11,1:1
10Indicators of biofilm development and activity in constructed wetlands microcosms显示文摘Ragusa S R McNevin D Qasem S 2004Water Research2004,38,12:1
11Indicators of Biofilm Development and Activity in Constructed Wetlands Microcosms 显示文摘Ragusa S R McNevin D Qasem S 2004Water Research2004,38,12:1
12Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors 显示文摘Rimkus TK Carpenter RL Qasem S 2016Cancers (Basel)2016,8,2:1
13Detection of pressure buildup data dominated by wellbore phase re distribution effects显示文摘 NASHAWI I S MIRT M I 2002Journal of Petroleum Science and Engineering2002,,34:1
14Indicators of biofilm development and activity in constructed wetlands microcosms 显示文摘Ragusa S R McNevin D Qasem S 2004Water Res2004,38,12:1
15Indicators of biofilm development and activity in constructed wetlands microcosms 显示文摘Ragusa S R McNevin D Qasem S 2004Water Research2004,38,12:1
16Indicators of Development and Activity in Constructed Wetlands Micro- cosms 显示文摘RAGUSA S R MCNEVIN D QASEM S 2004Water Res2004,38,12:1
17An improved pattern search based algorithm to solve the dynamic economic dispatch problem with value point effect显示文摘ALSUMAIT J S QASEM M SYKULSKI J K 2010Energy Conversion Management2010,51,10:1
18Indicators of biofilm development and activity in constructed wetlands microcosms 显示文摘Ragusa S R McNevin D Qasem S 2004Water Reserch2004,38,12:1
19Indicators of biofilm development and activity in constructed wetlands microcosms 显示文摘Ragusa S R McNevin D Qasem S 2004Wat Res2004,38,12:1
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