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| 1 | Mild closed head traumatic brain injury-induced changes in monoamine neurotransmitters in the trigeminal subnuclei of a rat model:mechanisms underlying orofacial allodynias and headache显示文摘Our recent findings have demonstrated that rodent models of closed head traumatic brain injury exhibit comprehensive evidence of progressive and enduring orofacial allodynias, a hypersensitive pain response induced by non-painful stimulation. These allodynias, tested using thermal hyperalgesia, correlated with changes in several known pain signaling receptors and molecules along the trigeminal pain pathway, especially in the trigeminal nucleus caudalis. This study focused to extend our previous work to investigate the changes in monoamine neurotransmitter immunoreactivity changes in spinal trigeminal nucleus oralis, pars interpolaris and nucleus tractus solitaries following mild to moderate closed head traumatic brain injury, which are related to tactile allodynia, touch-pressure sensitivity, and visceral pain. Our results exhibited significant alterations in the excitatory monoamine, serotonin, in spinal trigeminal nucleus oralis and pars interpolaris which usually modulate tactile and mechanical sensitivity in addition to the thermal sensitivity. Moreover, we also detected a robust alteration in the expression of serotonin, and inhibitory molecule norepinephrine in the nucleus tractus solitaries, which might indicate the possibility of an alteration in visceral pain, and existence of other morbidities related to solitary nucleus dysfunction in this rodent model of mild to moderate closed head traumatic brain injury. Collectively, widespread changes in monoamine neurotransmitter may be related to orofacial allodynhias and headache after traumatic brain injury. | Golam Mustafa Jiamei Hou Rachel Nelson Shigeharu Tsuda Mansura Jahan Naweed S.Mohammad Joseph V.Watts Floyd J.Thompson Prodip Bose | 2017 | Neural Regeneration Research2017，12，6： | 5 |
| 2 | A three-dimensional agglomerate model for the cathode catalyst layer of PEM fuel cells显示文摘 | Prodip K D Li X G Liu Z S | 2008 | Journal of Power Sources2008，179，1： | 1 |
| 3 | Modeling and Simulation of Hydraulic Gap Control System in a Hot Strip Mill显示文摘 | Prodip BHOWAL | 1996 | ISIJ International1996，39，： | 1 |
| 4 | Estimating micro - PLC execution time for time critical system design 显示文摘 | Bhowal Prodip | 1999 | Journal of Systems Architecture1999，45，7： | 1 |
| 5 | Estimating micro-PLC execution time for time critical system design显示文摘 | Prodip Bhowal | 1999 | Journal of Systems Architecture1999，，45： | 1 |
| 6 | 显示文摘 | Prodip KR Witmar M Michael C R et aL Five new diterpenoids from an Okiuawan soft coral Cespitularia sp | 2012 | Mar Drugs2012，10，12： | 1 |
| 7 | Estimating micro-PLC execution time for time critical system design显示文摘 | BHOWAL PRODIP | 1999 | Journal of Systems Architecture1999，45，14： | 1 |
| 8 | Eslimating Micro-PLC Execution Time for Time Critical System Design 显示文摘 | Bhowal Prodip | 1999 | Journal of Systems Architecture1999，45，7： | 1 |
| 9 | Clinical studies on the effect of Neem ( Azadirachta indica ) bark extract on gastric secretion and gastroduodenal ulcer显示文摘 | Uday Bandyopadhyay Kaushik Biswas Arnab Sengupta Puspa Moitra Prodip Dutta Dipankar Sarkar Pratip Debnath Chayan K. Ganguly Ranajit K. Banerjee | 2004 | Life Sciences2004，，24： | 1 |
| 10 | Reduction of epinephrine in the lumbar spinal cord following repetitive blast-induced traumatic brain injury in rats显示文摘Traumatic brain inju ry-induced unfavorable outcomes in human patients have independently been associated with dysregulated levels of monoamines,especially epinephrine,although few preclinical studies have examined the epinephrine level in the central nervous system after traumatic brain injury.Epinephrine has been shown to regulate the activities of spinal motoneurons as well as increase the heart rate,blood pressure,and blood flow to the hindlimb muscles.Therefore,the purpose of the present study was to determine the impact of repeated blast-induced traumatic brain injury on the epinephrine levels in seve ral function-s pecific central nervous system regions in rats.Following three repeated blast injuries at 3-day intervals,the hippocampus,motor cortex,locus coeruleus,vestibular nuclei,and lumbar spinal cord were harvested at post-injury day eight and processed for epinephrine assays using a high-sensitive electrochemical detector cou pled with high-performance liquid chromatography.Our results showed that the epinephrine levels were significantly decreased in the lumbar spinal cord tissues of blast-induced traumatic brain injury animals compared to the levels detected in age-and sex-matched sham controls.In other function-specific central nervous system regions,although the epinephrine levels were slightly altered following blast-induced tra u matic brain injury,they were not statistically significant.These results suggest that blast injury-induced significant downregulation of epinephrine in the lumbar spinal cord could negatively impact the motor and cardiovascular function.This is the first repo rt to show altered epinephrine levels in the spinal cord following repetitive mild blast-induced traumatic brain injury. | Shigeharu Tsuda Mustafa Golam Jiamei Hou Kevin K.W.Wang Floyd J.Thompson Prodip Bose | 2024 | Neural Regeneration Research2024，19，7： | 0 |
| 11 | Numerical Prediction of Fluid Flow and Heat Transfer in a Wavy Pipe显示文摘Hydrodynamic and thermal characteristics in a pipe with sinusoidal wavy surface for steady laminar flow are invdtigted numerically in the present study. The integral forms of governing equations are discretized using control volume based Finite Volume method with collocated variable arrangement, SIMPLE algorithm is used and TDMA solver is applied for solution of system of equations. A pipe of length equal to 4λ is considered. Effect of surface waviness, determined by wavelength-amplitude ratio λ/a (=L), on flow and thermal field is presented. The simulation work has been carried out for L’=11.0 -30.0 for a Reynolds number range50 to 2000. Results are presented in the form of Streamfunction, isothermal lines, velocity and vorticity profiles, change of mean friction factor, variation in skin fiction. local and average Nusselt number with Reynolds number, wave number (n) and L’. For a particular geometry. length of circulation zone increases with Reynolds number and approaches a limiting value for higher Reynolds number. Wall shear stress in the bulge part of the chancel shows smaller values that affect largely the be of heat transfer and Nusselt number shows minimum values in this region. This circulation zone drastically increases with the increase of surface waviness showing high mean friction factor per wavelength. Mean friction factor inversely varies with Reynolds number. A correlation is proposed for calculating friction factor in the form f=C/(Re)m, where ’C and ’m’ represents two polynomials of degree 4 and 2 respectively and are function of L. Higher waviness of the surface shows the higher heat transfer rate than lower waviness. Heat transfer rate falls almost exponentially along the axial direction with the increase of wave number. | Shohel Mahmud A.K.M. Sadrul Islam Prodip Kumar Das Department of Mechanical Engineering, Bangladesh University of Engineering & Technology, BUET, Dhaka-1000, Bangladesh | 2001 | Journal of Thermal Science2001，10，2： | 0 |
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