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| 1 | Muhiscale modeling for polymer systems of industrial interest显示文摘 | FEMEGLIA M PRICL S | 2007 | Progesss in Origanic Coatings2007，58，3： | 1 |
| 2 | Multiscale molecular modeling in nanostructured material design and process system engineering显示文摘 | Maurizio Fermeglia Sabrina Pricl | 2009 | Computers and Chemical Engineering2009，，10： | 1 |
| 3 | Smoothened (SMO) receptor mutations dictate resistance to vismedegib in basal cell carcinoma显示文摘 | Pricl S Cortelazzi B Dal Col V | 2015 | Mol Oncol2015，9，2： | 1 |
| 4 | To the nanoscale, and beyond!显示文摘 | Giulio Scocchi Paola Posocco Andrea Danani Sabrina Pricl Maurizio Fermeglia | 2007 | Fluid Phase Equilibria2007，，1： | 1 |
| 5 | Multiscale modeling for polymer systems of industrial interest显示文摘 | Maurizio Fermeglia Sabrina Pricl | 2006 | Progress in Organic Coatings2006，，2： | 1 |
| 6 | The rise and fall of gatekeeper mutations? The BCR-ABL1 T315I paradigm显示文摘 | GIBBONS DL PRICL S KANTARJIAN H | 2012 | Cancer2012，118，2： | 1 |
| 7 | PET/PEN blends of industrial interest as barrier materials. Part I. Many-scale molecular modeling of PET/PEN blends显示文摘 | Maurizio Fermeglia Paolo Cosoli Marco Ferrone Stefano Piccarolo Giuseppe Mensitieri Sabrina Pricl | 2006 | Polymer2006，，16： | 1 |
| 8 | Computer simulation of nylon- 6/or- ganoclay nanocomposites: prediction of the binding energy 显示文摘 | Fermeglia M Ferrone M Pricl S | 2003 | Fluid Phase Equilibria2003，212，： | 1 |
| 9 | Functional analyses and molecular modeling of two c-kit mutations responsible for imatinib secondary resistance in gist patients显示文摘 | Tamborini E Pricl S Negri T | 2006 | Oncogene2006，25，45： | 1 |
| 10 | T3151-mutated Bcr-Abl in chronic myeloid leukemia and imatinib: insights from a i computational study 显示文摘 | Pricl S Fermeglia M Ferrone M | 2005 | Mol Cancer Ther2005，4，8： | 1 |
| 11 | Rheological modeling of fractal and dense suspensions 显示文摘 | Lapasin R Grassi M Pricl S | 1996 | The Chemical Engineering Journal1996，64，： | 1 |
| 12 | Computer-aided simulation of a dendrimer with a protoporphyrinic core as potential, novel hemoprotein mimic显示文摘 | Maurizio Fermeglia Marco Ferrone Sabrina Pricl | 2002 | Bioorganie & Medicinal Chemistry2002，10，8： | 1 |
| 13 | Shape Persistent Polyphenylene-based Dendrimers:a Computational Approach显示文摘 | Sabrina Pricl | 2003 | Polymeric Materials Science & Engineering2003，88，： | 1 |
| 14 | Predic- tion of thermophysieal properties of alternative refrigerams by computational chemistry 显示文摘 | Oliver Milocco Maurizio Fermeglia Sabrina Pricl | 2002 | Fluid Phase Equilibria2002，199，： | 1 |
| 15 | Rheological properties of polysaccharide solutions and derived printing pastes in continuous and oscillatory flow conditions显示文摘 | LAPASIN R PRICL S GRAZIOSI M et a/ | 1988 | Industrial and Engineering Chemis- try Research1988，27，： | 1 |
| 16 | Functional analyses and molecular modeling of two c-Kit mutations responsible for imatinib secondary resistance in GIST patients显示文摘 | Tambnrini E Pricl S Negri T | 2006 | Oncogene2006，25，45： | 1 |
| 17 | Multiscale modeling for polymer systems of industrial interest显示文摘 | FEMEGLIA M PRICL S | 2007 | Progress in Origanic Coatings2007，58，3： | 1 |
| 18 | An ionizable supramolecular dendrimer nanosystem for effective siRNA delivery with a favorable safety profile显示文摘Gene therapy using small interfering RNA(siRNA)is emerging as a novel therapeutic approach to treat various diseases.However,safe and efficient siRNA delivery still constitutes the major obstacle for clinical implementation of siRNA therapeutics.Here we report an ionizable supramolecular dendrimer vector,formed via self-assembly of a small amphiphilic dendrimer,as an effective siRNA delivery system with a favorable safety profile.By virtue of the ionizable tertiary amine terminals,the supramolecular dendrimer has a low positively charged surface potential and no notable cytotoxicity at physiological pH.Nonetheless,this ionizable feature imparted sufficient surface charge to the supramolecular dendrimer to enable formation of a stable complex with siRNA via electrostatic interactions.The resulting siRNA/dendrimer delivery system had a surface charge that was neither neutral,thus avoiding aggregation,nor too high,thus avoiding cytotoxicity,but was sufficient for favorable cellular uptake and endosomal release of the siRNA.When tested in different cancer cell lines and patient-derived cancer organoids,this dendrimer-mediated siRNA delivery system effectively silenced the oncogenes Myc and Akt2 with a potent antiproliferative effect,outperforming the gold standard vector,Lipofectamine 2000.Therefore,this ionizable supramolecular dendrimer represents a promising vector for siRNA delivery.The concept of supramolecular dendrimer nanovectors via self-assembly is new,yet easy to implement in practice,offering a new perspective for supramolecular chemistry in biomedical applications. | Dinesh Dhumal Wenjun Lan Ling Ding Yifan Jiang Zhenbin Lyu Erik Laurini Domenico Marson Aura Tintaru Nelson Dusetti Suzanne Giorgio Juan Lucio Iovanna Sabrina Pricl Ling Peng | 2021 | Nano Research2021，14，7： | 1 |
| 19 | Functional analyses and molecular modeling of two c-Kit mutations responsi- ble for imatinib secondary resistance in GIST patients 显示文摘 | Tamborini E Pricl S Negri T | 2006 | Oncogene2006，25，45： | 1 |
| 20 | Computer simulation of nylon-6/ organoday nanocomposites: Prediction of the binding energy 显示文摘 | Fermeglia M Ferrone M Pricl S | 2003 | Fluid Phase Equilibria2003，212，1： | 1 |
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