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| 1 | The determinants of national innovative capacity显示文摘 | Jeffrey L Furman Michael E Porter Scott Stern | 2002 | Research Policy2002,,6: | 12 |
| 2 | 单髁与全膝关节置换治疗内侧间室膝骨关节炎:5年假体在位率比较显示文摘背景:单髁置换越来越多的被应用于治疗单纯内侧胫股间室型膝关节骨关节炎。目的:比较膝关节单髁置换与全膝关节置换对膝关节单纯内侧间室骨关节炎的修复效果。方法:纳入单纯内侧间室型膝关节骨关节炎患者109例,根据修复方式分为两组,单髁置换组41例,全膝关节置换组68例。比较两组患者的平均住院时间、置换后并发症发生率、身体健康总评分、精神健康总评分、牛津膝关节评分以及置换后5年假体在位率。结果与结论:单髁置换组患者平均住院时间(4.21±2.44)d,较全膝关节置换组(6.11±2.23)d短(P=0.001)。两组患者置换后并发症发生率、身体健康总评分、精神健康总评分、牛津膝关节评分等方面差异均无显著性意义(P>0.05)。置换后5年,单髁置换组假体在位率(90%)较全膝关节置换组(100%)低(P<0.05)。提示对于单纯内侧胫股间室型膝关节骨关节炎患者,单髁置换与全膝关节置换具有相似的修复效果,但单髁置换后5年假体在位率稍低。 | 梁宁 Samuel Yih Shyan Wong Nick Clement Deborah MacDonald Daniel E Porter | 2015 | 中国组织工程研究2015,19,53: | 12 |
| 3 | 慢性肾脏病中的炎症和动脉硬化:慢性肾功能不全队列研究中的发现显示文摘慢性肾脏病(chronic kidney disease,CKD)和动脉硬化程度与心血管病发病率和死亡率增加相关。目前认为炎症在动脉硬化发展中发挥作用,而CKD被认为是一种促炎症反应的状态。CKD患者的动脉僵硬度增加,横断面数据提示CKD中增多的炎症标志物与较高动脉僵硬度值相关。 | Peyster E Chen J Feldman HI Go AS Gupta J Mitra N Pan Q Porter A Rahman M Raj D Reilly M Wing MR Yang W Townsend RR 陈云 叶鹏 | 2017 | 中华高血压杂志2017,25,11: | 12 |
| 4 | Tenascin C upregulates interleukin-6 expression in human cardiac myofibroblasts via toll-like receptor 4显示文摘AIM:To investigate the effect of Tenascin C(TNC)on the expression of pro-inflammatory cytokines and matrixmetalloproteinases in human cardiac myofibroblasts(CMF).METHODS:CMF were isolated and cultured from patients undergoing coronary artery bypass grafting.Cultured cells were treated with either TNC(0.1μmol/L,24 h)or a recombinant protein corresponding to different domains of the TNC protein;fibrinogen-like globe(FBG)and fibronectin typeⅢ-like repeats(TNⅢ5-7)(both 1μmol/L,24 h).The expression of the proinflammatory cytokines;interleukin(IL)-6,IL-1β,TNFαand the matrix metalloproteinases;MMPs(MMP1,2,3,9,10,MT1-MMP)was assessed using real time RT-PCR and western blot analysis.RESULTS:TNC increased both IL-6 and MMP3(P<0.01)mR NA levels in cultured human CMF but had no significant effect on the other markers studied.The increase in IL-6 mR NA expression was mirrored by an increase in protein secretion as assessed by enzymelinked immunosorbant assay(P<0.01).Treating CMF with the recombinant protein FBG increased IL-6mR NA and protein(P<0.01)whereas the recombinant protein TNⅢ5-7 had no effect.Neither FBG nor TNⅢ5-7 had any significant effect on MMP3 expression.The expression of toll-like receptor 4(TLR4)in human CMF was confirmed by real time RT-PCR,western blot and immunohistochemistry.Pre-incubation of cells with TLR4neutralising antisera attenuated the effect of both TNC and FBG on IL-6 mR NA and protein expression.CONCLUSION:TNC up-regulates IL-6 expression in human CMF,an effect mediated through the FBG domain of TNC and via the TLR4 receptor. | Azhar Maqbool Emma J Spary Iain W Manfield Michaela Ruhmann Lorena Zuliani-Alvarez Filomena O Gamboa-Esteves Karen E Porter Mark J Drinkhill Kim S Midwood Neil A Turner | 2016 | World Journal of Cardiology2016,8,5: | 4 |
| 5 | The effect of liquid channeling on distillation plate efficiency显示文摘 | Porter K E Lockett M J Lim C T | 1972 | Trans IchemE1972,50,: | 2 |
| 6 | Broad-spectrum antimicrobial activity of human intestinal defensin 5显示文摘 | Porter EM van Dam E Valre EV | 1997 | J Immunol1997,65,6: | 2 |
| 7 | Clusters and the New Economics of Competition显示文摘 | Porter Michael E | 1998 | Harvard Business Review1998,98,: | 1 |
| 8 | Competitive Advantage, Aggloraeration Economies and Regional Policy显示文摘 | Porter M E | 1996 | International Regional Science Review1996,,19: | 1 |
| 9 | How Competitive Forces Shape Strategy显示文摘 | | 1979 | Harvard Business Review1979,57,2: | 1 |
| 10 | Towards a Dynamic Theory of Strategy显示文摘 | | 1991 | Strategic Management Journal1991,12,: | 1 |
| 11 | Partition equilibriums of nonionic organic compounds between soil organic matter and water显示文摘 | Chiou C T Porter P E Schmedding D W | 1983 | Environ Sci Technol1983,17,: | 1 |
| 12 | Therapeutic applications of lipid-coated microbubbles显示文摘 | UNGER E C PORTER T CULP W | 2004 | Adv Drug Deliv Rev2004,56,9: | 1 |
| 13 | Tract-based spatialstatistics of magnetic resonance images to assess disease andtreatment effects in perinatal asphyxial encephalopathy 显示文摘 | Porter E J Counsell SJ Edwards AD | 2010 | Pediatr Res2010,68,: | 1 |
| 14 | Colorado potato beetle response to soil amendments:A case in support of the mineral balance hypothesis?显示文摘 | Alyokhin A Porter G Groden E Drummond F | 2005 | Agriculture Ecosystems and Environment2005,109,: | 1 |
| 15 | Localization of human intestinal defensin 5 in Paneth cell granules显示文摘 | Porter E Liu L Oren A | 1997 | Infect Immun1997,65,: | 1 |
| 16 | Controlling growth of common carpet grass using selected plant growth regulators显示文摘 | Bush E W Porter W C | 1998 | Hortscience1998,33,4: | 1 |
| 17 | Cluster and New Economics of Competition显示文摘 | PORTER M E | 1998 | Harvard Business Review1998,,11: | 1 |
| 18 | Ousters and the New Economics of Competition 显示文摘 | Porter M E | 1998 | Harvard Business Review1998,76,6: | 1 |
| 19 | Mechanisms of free radical oxidation of unsaturated lipids 显示文摘 | Porter N A Caldwell S E Mills K A | 1995 | Lipids1995,30,4: | 1 |
| 20 | Clusters and new economics of competition 显示文摘 | M E PORTER | 1998 | Harvard Business Review1998,,2: | 1 |