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| 1 | Laparoscopic fundoplication for gastroesophageal reflux disease显示文摘Gastroesophageal reflux disease(GERD) is a condition that develops when the reflux of gastric contents into the esophagus leads to troublesome symptoms and/or complications. Heartburn is the cardinal symptom, often associated with regurgitation. In patients with endoscopy-negative heartburn refractory to proton pump inhibitor(PPI) therapy and when the diagnosis of GERD is in question, direct reflux testing by impedance-pH monitoring is warranted. Laparoscopic fundoplication is the standard surgical treatment for GERD. It is highly effective in curing GERD with a 80% success rate at 20-year follow-up. The Nissen fundoplication, consisting of a total(360°) wrap, is the most commonly performed antireflux operation. To reduce postoperative dysphagia and gas bloating, partial fundoplications are also used, including the posterior(Toupet) fundoplication, and the anterior(Dor) fundoplication. Currently, there is consensus to advise laparoscopic fundoplication in PPI-responsive GERD only for those patients who develop untoward side-effects or complications from PPI therapy. PPI resistance is the real challenge in GERD. There is consensus that carefully selected GERD patients refractory to PPI therapy are eligible for laparoscopic fundoplication, provided that objective evidence of reflux as the cause of ongoing symptoms has been obtained. For this purpose, impedance-pH monitoring is regarded as the diagnostic gold standard. | Marzio Frazzoni Micaela Piccoli Rita Conigliaro Leonardo Frazzoni Gianluigi Melotti | 2014 | World Journal of Gastroenterology2014，20，39： | 10 |
| 2 | Single‐pixel terahertz imaging:a review显示文摘This paper is devoted to reviewing the results achieved so far in the application of the single-pixel imaging technique to terahertz(THz)systems.The use of THz radiation for imaging purposes has been largely explored in the last twenty years,due to the unique capabilities of this kind of radiation in interrogating material properties.However,THz imaging systems are still limited by the long acquisition time required to reconstruct the object image and significant efforts have been recently directed to overcome this drawback.One of the most promising approaches in this sense is the so-called“single-pixel”imaging,which in general enables image reconstruction by patterning the beam probing the object and measuring the total transmission(or reflection)with a single-pixel detector(i.e.,with no spatial resolution).The main advantages of such technique are that i)no bulky moving parts are required to raster-scan the object and ii)compressed sensing(CS)algorithms,which allow an appropriate reconstruction of the image with an incomplete set of measurements,can be successfully implemented.Overall,this can result in a reduction of the acquisition time.In this review,we cover the experimental solutions proposed to implement such imaging technique at THz frequencies,as well as some practical uses for typical THz applications. | Luca Zanotto Riccardo Piccoli Junliang Dong Roberto Morandotti Luca Razzari | 2020 | Opto-Electronic Advances2020，3，9： | 4 |
| 3 | Exploitation of host clock gene machinery by hepatitis viruses B and C显示文摘Many aspects of cellular physiology display circadian(approximately 24-h)rhythms.Dysfunction of the circadian clock molecular circuitry is associated with human health derangements,including neurodegeneration,increased risk of cancer,cardiovascular diseases and the metabolic syndrome.Viruses triggering hepatitis depend tightly on the host cell synthesis machinery for their own replication,survival and spreading.Recent evidences support a link between the circadian clock circuitry and viruses’biological cycle within host cells.Currently,in vitro models for chronobiological studies of cells infected with viruses need to be implemented.The establishment of such in vitro models would be helpful to better understand the link between the clock gene machinery and viral replication/viral persistence in order to develop specifically targeted therapeutic regimens.Here we review the recent literature dealing with the interplay between hepatitis B and C viruses and clock genes. | Manlio Vinciguerra Gianluigi Mazzoccoli Claudia Piccoli Tiziana Tataranni Angelo Andriulli Valerio Pazienza | 2013 | World Journal of Gastroenterology2013，19，47： | 2 |
| 4 | Is Renal Warm Ischemia over 30 Minutes during Laparoscopic Partial Nephrectomy Possible? One-Year Results of a Prospective Study显示文摘 | Francesco Porpiglia Julien Renard Michele Billia Francesca Musso Alessandro Volpe Rodolfo Burruni Carlo Terrone Loredana Colla Giorgina Piccoli Valerio Podio Roberto Mario Scarpa | 2007 | European Urology2007，，4： | 2 |
| 5 | 在高温和高能脉冲离子束辐射下离子渗碳和离子渗氮生成的扩张奥氏体的稳定性显示文摘奥氏体不锈钢用离子渗碳或离子渗氮能生成扩张的奥氏体。两种工艺得到的过饱和碳或氮的fcc晶体结构能很好地硬化,提高耐磨性,且保持原有的耐蚀性能。在本项研究中我们在AISI 316L SS不锈钢上在高温(225~504℃)和高能(30~500 keV),高通量(~1015cm-2),短时间保温(~400 ns),轻离子束(氘和氦)的辐射下,用离子渗碳和离子渗氮渗入N和C生成扩张的奥氏体,并研究它的稳定性。发现扩张的奥氏体在325℃以下是稳定的,在325℃和504℃之间,随温度升高它的晶格常数逐渐减小。我们观察到显微组织只和处理温度有关,由于热处理时间不长,没有观察到组织变化。超过504℃晶格常数回复到奥氏体材料原来的晶格常数。另一方面,观察到当用脉冲离子束时,随着脉冲数减少扩展奥氏体的晶格常数也减小。这种行为可以解释为通过由每束辐射作用在表面上因热振动,包括快速加热然后快速冷却引起N或C逐渐外扩散。然而发现经过20个离子脉冲后最终的晶格常数比原始奥氏体的略高一些,这是稳定的极限。这个残余的扩张量是由于在紧靠表面层的奥氏体晶体中产生应力引起几微米的部分非晶化的结果。 | Molleja J G Milanese M Piccoli M Moroso R Niedbalski J Nosei L Bürgi J Bemporad E Feugeas J | 2013 | 热处理技术与装备2013，34，5： | 2 |
| 6 | Immune Response to Influenza Vaccine in Pediatric Patients With Inflammatory Bowel Disease显示文摘 | Petar Mamula Jonathan E. Markowitz David A. Piccoli Alexander Klimov Louis Cohen Robert N. Baldassano | 2007 | Clinical Gastroenterology and Hepatology2007，，7： | 2 |
| 7 | Discriminating between body fat and fluid changes in the obese adult using bioimpedance vector analysis显示文摘 | Piccoli A Brunani A Savia G | 1998 | Int J Obes Relat Metab Disord1998，22，： | 1 |
| 8 | Manumglin inhibits farnesyltransferase and induces apoptosis of drug-resistant interleukin 6-producing myeloma cues显示文摘 | Frassanito MA Cusmai A Piccoli C | 2002 | Br J Haematol2002，118，1： | 1 |
| 9 | Cystatin C in heart fail- ure is nothing more than a bystander of glomeruLar filtration 显示文摘 | Codognotto M Piccoli A Zaninotto M | 2007 | J Nephro12007，20，2： | 1 |
| 10 | Hepatitis C virus protein expression causes calcium - mediated mitochondrial bioenergetic dysfunction and nitro - oxidative stress显示文摘 | Piccoli C Scrima R Quarato G | 2007 | Hepatology2007，46，1： | 1 |
| 11 | p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicityand cytokine production in human NK cells 显示文摘 | Pisegna S Pirozzi G Piccoli M | 2004 | Blood2004，104，13： | 1 |
| 12 | Chronic kidney disease, severe arterial and arteriolar sclerosis and kidney neoplasia: on the spectrum of kidney involvement in MELAS syndrome显示文摘 | Piccoli GB Bonino LD Campisi P | 2012 | BMC Nephrol2012，13，： | 1 |
| 13 | Influence of tonsillectomy on the progression of mesangiopmliferative glomerulonephritis 显示文摘 | Piccoli A Codognotto M Tabbi MG | 2010 | Nephrol Dial Transplant2010，25，8： | 1 |
| 14 | Tectonic discrimination of granitoids显示文摘 | Maniar P D Piccoli | 1989 | GSA Bulletin1989，101，5： | 1 |
| 15 | Survival after resection for ductual adenocarcinoma of the pancreas显示文摘 | Sperti C Pasquali C Piccoli A | 1996 | Br J Surg1996，83，5： | 1 |
| 16 | Phase I study of subconjunctival ranibizumab in patients with primary pterygium undergoing pterygium surgery显示文摘 | Galor A Yoo SH Piccoli FV | | 0，，： | 1 |
| 17 | Bacterial vaginosis and preterm delivery : an open question 显示文摘 | De - Seta F Sartore A Piccoli M | 2005 | J Reprod Med2005，50，： | 1 |
| 18 | Manumycin inhibits farnesyltransferase and induces apoptosis of drug-resistant interleukin 6-producing myeloma cells显示文摘 | Frassanito MA Cusmai A Piccoli C | 2002 | Br J Haematol2002，118，1： | 1 |
| 19 | Manumycin inhibits farnesyl-transferase and induces apoptosis of drug-resistant interleukin 6-producing myeloma cells显示文摘 | Franssani MA Cusmai A Piccoli C | 2002 | Br J Haematol2002，188，1： | 1 |
| 20 | Evaluation of Neck and Body Metastases to Nodes with Ferumoxtran 10 Enhanced MR Imaging:Phase Ⅲ Safety and Efficacy Study显示文摘 | Yoshimi A Catherine W Piccoli M | 2003 | Radiology2003，228，3： | 1 |
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