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| 1 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 2 | Storage of Light in Atomic Vapor显示文摘 | Philips D F Fleischhauer A Mair A | 2001 | Phys Rev Lett2001，86，5： | 1 |
| 3 | A Refinement of Inverse Distance Weigh- ted Interpolation显示文摘 | Watson D F Philip G M | 1985 | Geoprocessing1985，，2： | 1 |
| 4 | A refinement of inverse distance weighted interpolation 显示文摘 | Watson D F Philip G M | 1985 | Geo-Processing1985，2，4： | 1 |
| 5 | Increased incidence of differentiated thyroid carcinoma and detection of subclinical disease显示文摘 | WILLIAM D T STEPHEN F PHILIP A | 2007 | Candian Medical Association Journal2007，177，11： | 1 |
| 6 | A Refinement of Inverse Distance Weighted Interpolation 显示文摘 | Watson D F Philip G M | 1985 | Geographic Processing1985，2，： | 1 |
| 7 | A precise method for determining contoured surfaces 显示文摘 | Philip G M Watson D F | 1982 | Australian Petroleum Exploration Association Journal1982，22，： | 1 |
| 8 | A refinement of inverse distance weigh- ted interpolation显示文摘 | Watson D F Philip G M | 1985 | Geoprocessing1985，2，： | 1 |
| 9 | The accumulation of cosmogenic chlorine-36 in rocks: A method for surface exposure dating 显示文摘 | Philips F M Leavy B D Jannik N O | 1986 | Science1986，231，： | 1 |
| 10 | Toxicity of Antimycin A to fish显示文摘 | PHILIP H D STRONG F M | 1963 | Nature1963，200，： | 1 |
| 11 | Changing contaminant mobility in a dredged canal sediment during a three - year phytoremediation trial显示文摘 | Rosalind F King Anna Royle Philip D Putwain | 2006 | Environmental Pollution2006，14，3： | 1 |
| 12 | Prevention of aflatoxieosis by addition of hydrated sodium calcium aluminositicate to the diets of growing barrows显示文摘 | Harvey R B Kubena L F Philips T D Huff W E Corrier D E | 1989 | Am J Vet Res1989，50，： | 1 |
| 13 | Expression studies on four members of the pMGA multigene family in Mycoplasma gallisepticum S6显示文摘 | Michelle D Glew Philip F Markham | 1995 | Micro1995，141，： | 1 |
| 14 | Special issue: Navigating complexity显示文摘 | Philips F Drake D | 2000 | Technological Forecasting and Social Change2000，64，1： | 1 |
| 15 | A refinement of inverse distance weight interpolation显示文摘 | Watson D F Philip G M | 1985 | Geo-Processing1985，，2： | 1 |
| 16 | Arefinernent of Inverse Distance Weighted Interpolation显示文摘 | Watson D F Philip G M | 1982 | Comp & Maths with Appls1982，8，2： | 1 |
| 17 | The Bias of the ordinary least squares estimator in simultaneous equation models显示文摘 | Kiviet Jan F Garry D Philips | | 0，，： | 1 |
| 18 | Prevalence of hepatitis E virus antibodies in Canadian swine herds and identification of a novel variant of swine hepatitis E virus显示文摘 | Philip W Yanlong P M Anthony H Anne D Catherine E D Robert M F Yungho Y Marcelo G Carmencita Y Antonio G | 2001 | Clinical and Diagnostic Laboratory Immunology2001，8，6： | 1 |
| 19 | Inheritance of delayed leaf senescence in soybean显示文摘 | Pierce R O Knowles P F Philips D A | 1984 | Crop Science1984，24，： | 1 |
| 20 | Reduction of aflatoxins in peanut meal by extrution cooking in the presence of nucleophiles 显示文摘 | Saalia F K Philips R D | 2011 | LWT - Food Science and Technology2011，44，： | 1 |
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