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| 1 | Real-time RT-PCR detection of disseminated tumour cells in bone marrow has superior prognostic significance in comparison with circulating tumour cells in patients with breast cancer 显示文摘 | BENOY I H E1ST H PHILIPS M | 2006 | Br J Cancer2006，94，5： | 1 |
| 2 | Real-time RT-PCR detection of disseminated tumour cells in bone marrow has superior prognostic significance in comparison with circulating tumour cells in patients with breast cancer显示文摘 | Benoy I H Elst H Philips M | 2006 | Br J Cancer2006，94，： | 1 |
| 3 | Underpotential deposition and its relation to the anomalous deposition of metals in alloys 显示文摘 | Nicol M J Philip H I | 1976 | J Electroanal Chem1976，70，： | 1 |
| 4 | Real-time RT-PCR detection of disseminated tumour cells in bone marrow has superior prognostic significance in comparison with circulatingtumour cells in patients with breast cancer显示文摘 | Benoy I H Elst H Philips M | 2006 | British Journal of Cancer2006，94，： | 1 |
| 5 | New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects显示文摘 | Alimuddin I Zumla Stephen H Gillespie Michael Hoelscher Patrick P J Philips Stewart T Cole Ibrahim Abubakar Timothy D McHugh Marco Schito Markus Maeurer Andrew J Nunn | 2014 | The Lancet Infectious Diseases2014，，4： | 1 |
| 6 | Incidence and patterns of recurrence following curative resection for colorectal carcinoma 显示文摘 | Daniel I Philip H | 1997 | Dis Colon Rectum1997，40，： | 1 |
| 7 | Prognostic significance of disseminated tumor cells as detected by quantitative real time reverse-transcriptase polymerase chain reaction in patients with breast cancer显示文摘 | Benoy I H Elst H Philips M | 2006 | Clin Breast Cancer2006，7，2： | 1 |
| 8 | Setting priorities for measures of performance for geriatric medical services显示文摘 | Roberts H Khee TS Philip I | 1994 | Age ageing1994，23，2： | 1 |
| 9 | Systematic molecular and cytogenetic screening of 100 patients with marfanoid syndromes and intellectual disability显示文摘 | P Callier B Aral N Hanna S Lambert H Dindy C Ragon M Payet G Collod‐Beroud V Carmignac MA Delrue C Goizet N Philip T Busa Y Dulac I Missotte Y Sznajer A Toutain C Francannet A Megarbane S Julia T Edouard P Sarda J Amiel S Lyonnet V Cormier‐Daire B Gilbert | 2013 | Clin Genet2013，，6： | 1 |
| 10 | Na- ture and surface redox properties of copper(II)-pro- moted cerium(IV) oxide CO-oxidation catalysts显示文摘 | PHILIP G H BALL I K AZELEE W | 2000 | Chem Mater2000，12，12： | 1 |
| 11 | 显示文摘 | Entry J A Philips I Stratton H | 2003 | Environmental Pollution2003，121，： | 1 |
| 12 | Density functional theory in the solid state显示文摘 | PHILIP J H KEITH R MATT I J P | 2014 | Phil Trans R SocA2014，372，： | 1 |
| 13 | Incidence and patterns of recurrenee following curative resection for colorectal carcinoma 显示文摘 | Daniel I Obrand Philip H | 1997 | Dis Colon Rectum1997，40，1： | 1 |
| 14 | New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects显示文摘 | Alimuddin I Zumla Stephen H Gillespie Michael Hoelscher Patrick P J Philips Stewart T Cole Ibrahim Abubakar Timothy D McHugh Marco Schito Markus Maeurer Andrew J Nunn | 2014 | The Lancet Infectious Diseases2014，，4： | 1 |
| 15 | Real time RT-PCR detection of disseminated tumour cells in bone marrow has superior prognostic significance in comparison with circulating tumour cells in patients with breast cancer显示文摘 | Benoy I H Elst H Philips M | 2006 | Br J Cancer2006，94，5： | 1 |
| 16 | Expression of neurodevelopmental markers by cultured porcine neural precursor cells显示文摘 | PHILIP H S HUBERT N IVAN I K | 2005 | Stem Cells2005，23，9： | 1 |
| 17 | Antihypertensive prescribing patterns in non-dialysis dependent chronic kidney disease:Findings from the Salford Kidney Study显示文摘BACKGROUND Hypertension is commonly observed in patients living with chronic kidney disease(CKD).Finding an optimal treatment regime remains challenging due to the complex bidirectional cause-and-effect relationship between hypertension and CKD.There remains variability in antihypertensive treatment practices.AIM To analyze data from the Salford Kidney Study database in relation to antihypertensive prescribing patterns amongst CKD patients.METHODS The Salford Kidney Study is an ongoing prospective study that has been recruiting CKD patients since 2002.All patients are followed up annually,and their medical records including the list of medications are updated until they reach study endpoints[starting on renal replacement therapy or reaching estimated glomerular filtration rate(eGFR)expressed as mL/min/1.73 m2≤10 mL/min/1.73 m2,or the last follow-up date,or data lock on December 31,2021,or death].Data on antihypertensive prescription practices in correspondence to baseline eGFR,urine albumin-creatinine ratio,primary CKD aetiology,and cardiovascular disease were evaluated.Associations between patients who were prescribed three or more antihypertensive agents and their clinical outcomes were studied by Cox regression analysis.Kaplan-Meier analysis demonstrated differences in survival probabilities.RESULTS Three thousand two hundred and thirty non-dialysis-dependent CKD patients with data collected between October 2002 and December 2019 were included.The median age was 65 years.A greater proportion of patients were taking three or more antihypertensive agents with advancing CKD stages(53%of eGFR≤15 mL/min/1.73 m2 vs 26%of eGFR≥60 mL/min/1.73 m2,P<0.001).An increased number of patients receiving more classes of antihypertensive agents was observed as the urine albumin-creatinine ratio category increased(category A3:62%vs category A1:40%,P<0.001),with the upward trends particularly noticeable in the number of individuals prescribed renin angiotensin system blockers.The prescription of three or more antihypertensive agents was associated with all-cause mortality,independent of blood pressure control(hazard ratio:1.15;95%confidence interval:1.04-1.27,P=0.006).Kaplan-Meier analysis illustrated significant differences in survival outcomes between patients with three or more and those with less than three antihypertensive agents prescribed(log-rank,P<0.001).CONCLUSION Antihypertensive prescribing patterns in the Salford Kidney Study based on CKD stage were consistent with expectations from the current United Kingdom National Institute of Health and Care Excellence guideline algorithm.Outcomes were poorer in patients with poor blood pressure control despite being on multiple antihypertensive agents.Continued research is required to bridge remaining variations in hypertension treatment practices worldwide. | Rajkumar Chinnadurai Henry H L Wu Jones Abuomar Sharmilee Rengarajan David I New Darren Green Philip A Kalra | 2023 | World Journal of Nephrology2023，12，5： | 0 |
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